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Novel clinical applications of extracellular vesicles
During the last years, the research on extracellular vesicles (EVs) has raised giving new insights into pathophysiology of several diseases. EVs are membrane-bound particles secreted by almost all cell types. Depending on their biogenesis and size they include exosomes, microparticles / microvesicles and apoptotic bodies. Characteristically, EVs carry markers from the source cell membrane and contain genetic material, lipids and proteins inside. They are known to play a role in cell-to-cell communication and to produce genotypic and phenotypic modifications in the target cell including: antigen presentation, apoptosis induction, cellular activation, inhibition or differentiation. In particul...
Novel Clinical Applications of Extracellular Vesicles
During the last years, the research on extracellular vesicles (EVs) has raised giving new insights into pathophysiology of several diseases. EVs are membrane-bound particles secreted by almost all cell types. Depending on their biogenesis and size they include exosomes, microparticles / microvesicles and apoptotic bodies. Characteristically, EVs carry markers from the source cell membrane and contain genetic material, lipids and proteins inside. They are known to play a role in cell-to-cell communication and to produce genotypic and phenotypic modifications in the target cell including: antigen presentation, apoptosis induction, cellular activation, inhibition or differentiation. In particul...
Self Portrait in Green
'NDiaye is a hypnotic storyteller with an unflinching understanding of the rock-bottom reality of most people's life.' New York Times ' One of France's most exciting prose stylists.' The Guardian. Obsessed by her encounters with the mysterious green women, and haunted by the Garonne River, a nameless narrator seeks them out in La Roele, Paris, Marseille, and Ouagadougou. Each encounter reveals different aspects of the women; real or imagined, dead or alive, seductive or suicidal, driving the narrator deeper into her obsession, in this unsettling exploration of identity, memory and paranoia. Self Portrait in Green is the multi-prize winning, Marie NDiaye's brilliant subversion of the memoir. Written in diary entries, with lyrical prose and dreamlike imagery, we start with and return to the river, which mirrors the narrative by posing more questions than it answers.
Stem Cell Drugs - A New Generation of Biopharmaceuticals
This invaluable resource discusses the current revolution in stem cell-based drugs and their potential use in clinical applications. Each chapter is contributed by a pre-eminent scientist in the field. An introductory section presents current stem cell drugs and stem cell-based products and a discussion of production, quality control, mechanisms, and efficacy. Following sections include discussions on stem cell-derived microvesicles based products, and derived exosomes based products. Stem Cell Drugs - A New Generation of Biopharmaceuticals and the other books in the Stem Cells in Clinical Applications series are invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering. This groundbreaking volume is also essential reading for those researching or studying drug development or pharmaceutical science.
About Trees
About Trees considers our relationship with language, landscape, perception, and memory in the Anthropocene. The book includes texts and artwork by a stellar line up of contributors including Jorge Luis Borges, Andrea Bowers, Ursula K. Le Guin, Ada Lovelace and dozens of others. Holten was artist in residence at Buro BDP. While working on the book she created an alphabet and used it to make a new typeface called Trees. She also made a series of limited edition offset prints based on her Tree Drawings.
Labyrinth
Notable International Crime Novel of the Year – Crime Reads / Lit Hub From a prize-winning Turkish novelist, a heady, political tale of one man’s search for identity and meaning in Istanbul after the loss of his memory. A blues singer, Boratin, attempts suicide by jumping off the Bosphorus Bridge, but opens his eyes in the hospital. He has lost his memory, and can't recall why he wished to end his life. He remembers only things that are unrelated to himself, but confuses their timing. He knows that the Ottoman Empire fell, and that the last sultan died, but has no idea when. His mind falters when remembering civilizations, while life, like a labyrinth, leads him down different paths. From the confusion of his social and individual memory, he is faced with two questions. Does physical recognition provide a sense of identity? Which is more liberating for a man, or a society: knowing the past, or forgetting it? Embroidered with Borgesian micro-stories, Labyrinth flows smoothly on the surface while traversing sharp bends beneath the current.
A Revision of the Dulcamaroid Clade of Solanum L. (Solanaceae)
This volume is a monograph of the 47 species of the Dulcamaroid clade of the large and diverse genus Solanum. Species in the group occur in North, Central and South America, and in Europe and Asia. The group is most species-rich in Peru and Brazil, and three of the component species, Solanum laxum of Brazil, Solanum seaforthianum of the Caribbean and and Solanum crispum of Chile are cultivated in many parts of the world. All species are illustrated and a distribution map of each is provided. All names are typified and nomenclatural and bibliographic details for all typifications presented. One new species from Ecuador is described. The monograph is the first complete taxonomic treatment of these species since the worldwide monograph of Solanum done by the French botanist Michel-Felix Dunal in 1852.
The Mosquito Bite Author
Originally published in 2011, The Mosquito Bite Author is the seventh novel by the acclaimed Turkish author Barış Bıçakçı. It follows the daily life of an aspiring novelist, Cemil, in the months after he submits his manuscript to a publisher in Istanbul. Living in an unremarkable apartment complex in the outskirts of Ankara, Cemil spends his days going on walks, cooking for his wife, repairing leaks in his neighbor’s bathroom, and having elaborate imaginary conversations in his head with his potential editor about the meaning of life and art. Uncertain of whether his manuscript will be accepted, Cemil wavers between thoughtful meditations on the origin of the universe and the trajectory of political literature in Turkey, panic over his own worth as a writer, and incredulity toward the objects that make up his quiet world in the Ankara suburbs.
Killing the Water
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