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Genetics of Adaptation
An enduring controversy in evolutionary biology is the genetic basis of adaptation. Darwin emphasized "many slight differences" as the ultimate source of variation to be acted upon by natural selection. In the early 1900’s, this view was opposed by "Mendelian geneticists", who emphasized the importance of "macromutations" in evolution. The Modern Synthesis resolved this controversy, concluding that mutations in genes of very small effect were responsible for adaptive evolution. A decade ago, Allen Orr and Jerry Coyne reexamined the evidence for this neo-Darwinian view and found that both the theoretical and empirical basis for it were weak. Orr and Coyne encouraged evolutionary biologists to reexamine this neglected question: what is the genetic basis of adaptive evolution? In this volume, a new generation of biologists have taken up this challenge. Using advances in both molecular genetic and statistical techniques, evolutionary geneticists have made considerable progress in this emerging field. In this volume, a diversity of examples from plant and animal studies provides valuable information for those interested in the genetics and evolution of complex traits.
Decision Making, Affect, and Learning
This latest volume in the critically acclaimed and highly influential Attention and Performance series focuses on two of the fastest moving research areas in cognitive and affective neuroscience - decision making and emotional processing. Decision Making, Affect, and Learning investigates the psychological and neural systems underlying decision making, and the relationship with reward, affect, and learning. In addition, it considers neurodevelopmental and clinical aspects of these issues - for example the role of decision making and reward in drug addiction. It also looks at the applied aspects of this knowledge to other disciplines, including the growing field of Neuroeconomics. After an introductory chapter from the Volume editors, the book is then arranged according to the following themes: Psychological Processes underlying decision-making. Neural systems of decision-making Neural systems of emotion, reward and learning Neurodevelopmental and clinical aspects Superbly written and edited, the book highlights the complex interplay between emotional and decision-making processes and their relationship with learning.
Neurodegenerative Disorders as Systemic Diseases
This book sheds new light on neurodegenerative disorders as systemic diseases. Classically, neuronal cell death was a hallmark of such disorders. However, it has become evident that neural dysfunction is more important in the pathophysiology of neurodegenerative disorders. More recently, the prionoid-spreading hypothesis of disease-causing molecules has attracted a great deal of attention. Therapeutic strategies thus must be reconsidered in the light that neurodegenerative disorders are indeed systemic diseases. The first part of this book introduces the concept of neurodegeneration in biology and pathophysiology. The second part focuses on clinical evaluation and biomarkers from the perspective of this new concept, while the third summarizes the risk factors of neurodegeneration. The fourth part of this work indicates future directions of treatment, and the final part discusses health promotion for prevention and quality of life. This book will be of interest to both researchers and medical personnel, and provides a fresh approach to neurodegenerative diseases, paving the way to new research and improved quality of health care for patients.
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Population Genomics: Wildlife
Population genomics is revolutionizing wildlife biology, conservation, and management by providing key and novel insights into genetic, population and landscape-level processes in wildlife, with unprecedented power and accuracy. This pioneering book presents the advances and potential of population genomics in wildlife, outlining key population genomics concepts and questions in wildlife biology, population genomics approaches that are specifically applicable to wildlife, and application of population genomics in wildlife population and evolutionary biology, ecology, adaptation and conservation and management. It is important for students, researchers, and wildlife professionals to understand the growing set of population genomics tools that can address issues from delineation of wildlife populations to assessing their capacity to adapt to environmental change. This book brings together leading experts in wildlife population genomics to discuss the key areas of the field, as well as challenges, opportunities and future prospects of wildlife population genomics.
Evolution of Learning and Memory Mechanisms
This book examines how evolution influences learning and memory processes in both human and nonhuman animals.
2004 IUCN Red List of Threatened Species
Applies Red List data to calculate a Red List Index.
