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Insights into Genetic Retinal Diseases
This book is the definitive guide to cutting-edge research in genetic retinal diseases. This compilation brings together the collective wisdom of leading experts in the field, offering a comprehensive and up-to-date resource that is as enlightening as it is invaluable. The book focuses on next-generation sequencing, a revolutionary technology that has transformed our understanding of retinal diseases, and it delves deep into the intricacies of this rapidly evolving field, unearthing unknown genetic mutations that underlie these conditions and unveiling innovative diagnostic tools and treatments that hold the promise of transforming lives, as well as sharing the latest developments in a field that holds the key to preserving and restoring one of our most precious senses—vision. With a clear writing style, this book is accessible to researchers, clinicians, and anyone with a curiosity for unraveling the mysteries of genetic retinal diseases.
Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models
This book explores potential cellular drug targets for cancer therapy. The first couple of chapters describe conventional treatment (radiotherapy, chemotherapy, and immunotherapy) & detection (biosensors) strategies for cancer. In contrast, the subsequent chapters address the role of cyclin-dependent kinases and cell cycle regulatory proteins in the growth of cancer cells and their potential as target for cancer treatment. The book then discusses the regulation of various pro-apoptotic and anti-apoptotic proteins via chemotherapeutic drugs. In addition, it examines the molecular mechanisms that are critical for mediating autophagic cell death in cancer cells. It subsequently reviews the role of reactive oxygen (ROS) species during carcinogenesis and during chemotherapy, and the potential of anti-inflammatory routes for the development of new therapeutic modulators. Lastly, it describes therapeutic strategies that target the tumor microenvironment and various angiogenic pathways for the treatment of cancer and to develop personalized medicine. Given its scope, the book is valuable resource for oncologists, cancer researchers, clinicians, and pharmaceutical industry personnel.
Fungal Machines
This unique book explores fungi as sensors, electronic devices, and potential future computers, offering eco-friendly alternatives to traditional electronics. Fungi are ancient, widely distributed organisms ranging from microscopic single cells to massive mycelium spanning hectares. They possess senses similar to humans, detecting light, chemicals, gases, gravity, and electric fields. It covers fungal electrical activity, sensors, electronics, computing prototypes, and fungal language. Authored by leading experts from diverse fields, the book is accessible to readers of all backgrounds, from high-schoolers to professors. It reveals the remarkable potential of fungal machines while minimizing environmental impact.
Nanoparticles in Cancer Theranostics
This book comprehensively reviews the application of nanoparticles in cancer diagnosis and treatment. The introductory section provides a fundamental understanding of cancer biology, its global incidence and prevalence, and the intricate nano–bio interactions at the cellular level. The subsequent section discusses the pivotal role of nanoparticles in precise cancer detection, enhancing cancer imaging and serving as contrast agents for accurate diagnosis. It also presents cutting-edge nanotechnology-based methods for detecting HTLV-1 retroviruses. The following section covers the utilization of lipid-based nanoparticles, monoclonal antibodies, and advanced nanotherapeutics for targeted cancer treatments. This book is a useful resource for researchers, clinicians, and students in the fields of oncology and nanotechnology.
Microbes in Agri-Forestry Biotechnology
This book explores recent advances on the use of microbes for agri-forestry biotechnological applications. It provides technical concepts and discussions on the use of microorganisms for processes such as bioprocessing, bioremediation, soil enhancement, aquaponics advances, and plant-host symbiosis. The book provides an overview of the microbial approach to the tools and processes used in agriculture and forestry that make or modify products, improve plants for specific uses, and make use of livestock in agricultural systems. The authors discuss the main process conditions that enhance agri-forestry applications with the use of microbes and introduce the use of genetically modified (GM) microbes in agrobiotechnology. Finally, the authors explore the main technological advances in the production of secondary metabolites with potential applications in agri-forestry. This book is intended for biotechnologists, biologists, bioengineers, biochemists, microbiologists, food technologists, enzymologists, and related researchers.
AACR 2019 Proceedings: Abstracts 2749-5314
American Association for Cancer Research 2019 Proceedings: Abstracts 2749-5314 - Part B
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