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Marek's Disease
Marek's disease is a form of cancer of poultry caused by an important herpesvirus (MDV). It continues to be a threat to poultry health and welfare and worldwide losses are estimated to be US$ 1 billion annually. Marek's Disease provides a timely review of the problems of Marek's disease with descriptions of the complex viral life cycle, how MDV targets different types of white blood cells, and details of the virus structure, its genes and proteins. - The multiplicity of factors contributing to susceptibility is explored in detail - Vaccination - the problems arising from current vaccination strategies and how these can be improved and made sustainable in future - The lessons learned in the control of MD over the past 30 years, and how we can use MD as a model for other animal and human diseases is discussed
Teaching-Learning Contemporary Physics
This book presents research contributions focussing on the introduction of contemporary physics topics – mainly, but not exclusively, quantum physics – into high school currciula. Despite the important advances and discoveries in quantum physics and relativity which have revolutionized our views of nature and our everyday lives, the presence of these topics in high school physics education is still lacking. In this book physics education researchers report on the teaching and learning of quantum physics from different perspectives and discuss the design and use of different pedagogical approaches and educational pathways. There is still much debate as to what content is appropriate at hi...
The Pain Solution
DISCOVER A PROVEN PATH TO PAIN RELIEF With empathy and scientific savvy, pain expert Dr. Saloni Sharma offers a personalized and innovative five-step pain relief program built on what she calls “microboosts,” little steps that add up to big results. Illustrated with inspiring patient examples and personal stories, her drug-free plan will enable you to: • understand the unique factors contributing to your pain • develop a path to resuming your most cherished activities • add easy food microboosts to reduce inflammation and support your pain-fighting gut microbiome • move better, at home and at work, to release natural neurochemical painkillers • recharge and recover through sleep, mindfulness, stress reduction, and supportive social relationships More than just a road map to less pain, this is a guide to the greater joy, health, and well-being that every person deserves.
Angiogenesis, Lymphangiogenesis and Clinical Implications
Angiogenesis, the formation of new blood vessels, is fundamental for physiological processes such as embryonic and postnatal development, wound repair, and reproductive functions. Angiogenesis plays a major role in tumor growth and in several autoimmune and allergic disorders. Lymphangiogenesis, the formation of new lymphatic vessels, is also important for tumor growth, the formation of metastasis, and chronic inflammatory diseases. Judah Folkman, a pioneer in the study of angiogenesis, first proposed that macrophages and mast cells could be a relevant source of angiogenic factors. Since then, much effort has gone into the elucidation of the role of immune cells in the modulation of angiogen...
Mutant p53 and MDM2 in Cancer
This book provides the readers with an overview of research on p53, which has been shown to play a role in numerous crucial biological pathways in normal and cancer cells. Leading scientist in the field, who have all made direct contributions to the understanding of the molecular events underpinning p53 function, have been invited to contribute the various chapters, which discuss the current knowledge of the signaling cascades that are activated by mutations in p53 and overexpression of MDM2, frequently found in human cancer and are major causes of oncogenesis. This book features chapters on the molecular basis of oncogenesis induced by gain of function mutation of p53, signaling pathways induced by MDM2 overexpression, control of mutant or wild-type p53 function by MDM2 and MDMX, p53 mutation in hereditary cancer and structural aspects that activate mutant p53 which can be targeted by drug therapy. This book should be useful for scientists at all levels.
Tumor Prevention and Genetics III
This volume contains the majority of the invited keynote lectures presented by experts at the Third International Conference on Controversies in Tumor Prevention and Genetics on 12-14 February 2004 in St.Gallen, Switzerland. Together, they reveal the latest findings in oncogenetics and its relations to recent and future developments in primary and secondary tumor prevention, especially in breast, colon and lung cancer. All contributions are written and have been critically reviewed by internationally recognised leaders in the field.
Comprehensive Healthcare Simulation: Emergency Medicine
This is a practical guide to the use of simulation in emergency medicine training and evaluation. It covers scenario building, debriefing, and feedback, and it discusses the use of simulation for different purposes, including education, crisis resource management and interdisciplinary team training. Divided into five sections, the book begins with the historical foundations of emergency medicine, as well as education and learning theory. In order to effectively relay different simulation modalities and technologies, subsequent chapters feature an extensive number of practical scenarios to allow readers to build a curriculum. These simulations include pediatric emergency medicine, trauma, dis...
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