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Molecular Mechanisms in Cancer
Cancer is a major public health problem and much research is being conducted to develop effective treatments for various types of malignancies. In doing so, researchers must have comprehensive knowledge about what causes cancer. This book explains the mechanisms of different types of cancers in twelve chapters organized into three sections on oncogenes, tumor suppressor genes, and viral oncogenes.
DNA Methylation Mechanism
‘Simplicity is the ultimate sophistication’- Leonardo Da Vinci The methylation that occurs simply by attaching one or more methyl molecules to a DNA molecule continues to confuse the scientific world by creating highly complex molecular arrangements. Research on methylation mechanisms have discovered that this simple biochemical event (which adapts to the changing micro/macro environment of the organism, to diseases and even cancerous processes) has shown that it is actually not as simple as it seems. In the last 50 years, our efforts to understand these mechanisms and use them to benefit human beings have continued. With this book called “DNA methylation mechanism”, in which we try to explain the effects on every stage of life, we hope that we have been able to create a resource book for everyone interested in this field, from students who are interested, to amateurs and professionals.
Chromatin and Epigenetics
Genomics has gathered broad public attention since Lamarck put forward his top-down hypothesis of 'motivated change' in 1809 in his famous book "Philosophie Zoologique" and even more so since Darwin published his famous bottom-up theory of natural selection in "The Origin of Species" in 1859. The public awareness culminated in the much anticipated race to decipher the sequence of the human genome in 2002. Over all those years, it has become apparent that genomic DNA is compacted into chromatin with a dedicated 3D higher-order organization and dynamics, and that on each structural level epigenetic modifications exist. The book "Chromatin and Epigenetics" addresses current issues in the fields...
Lung Cancer
Among the deadliest type of cancers, lung cancer faces several challenges in diagnosis and treatment: late diagnosis and misdiagnosis, inadequate tumor sampling, and resistance development to current therapies, among others. Together with advances in the understanding of molecular features, factors, and mechanisms involved in initiation and tumor progression, important improvements have occurred in diagnostics and therapeutics in the shape of advances in molecular genotyping, procedures for sampling, new potential, and less invasive sources of samples for the diagnosis and development of new targeted therapies. The aim of this book is to provide an exciting read on strategies in the diagnosis and therapy of lung cancer.
Market Threads
What is a global market? How does it work? At a time when new crises in world markets cannot be satisfactorily resolved through old ideas, Market Threads presents a detailed analysis of the international cotton trade and argues for a novel and groundbreaking understanding of global markets. The book examines the arrangements, institutions, and power relations on which cotton trading and production depend, and provides an alternative approach to the analysis of pricing mechanisms. Drawing upon research from such diverse places as the New York Board of Trade and the Turkish and Egyptian countrysides, the book explores how market agents from peasants to global merchants negotiate, accept, rejec...
Kızıl Elma (Pal Fodor)
Kızılelma, Osmanlı dünya hâkimiyeti düşüncesini ifade eder. Önce İstanbul, buranın fethinden sonra ise sırasıyla Belgrad ve Viyana'yı hedef alan bir idealdir. Kızılelma, başka bir açıdan ise Osmanlı İmparatorluğu'nun hâkimiyet kurduğu bölgelerdeki idarî nizamını ve devletin vatandaşlarına muamelelerini de ifade eder. Bu kitapta Avrupa'nın önde gelen Osmanlı tarihçilerinden Prof. Dr. Pál Fodor, Osmanlı Kızılelması'nı ele alır. Okuyucu bu kitapta, usta bir tarihçinin Osmanlı fetih ideolojisinde Macaristan ve Viyana; Macarların gözünden Türkler ve Kızıl Elma efsanesi; 1520-1541 yılları arasında Macaristan'a yönelik Osmanlı siyaseti; Macaristan'daki Osmanlı idaresi ve askerî teşkilatı; 15 ile 17 yüzyıl nasihatnâmelerine göre Osmanlı devlet ve toplumu; 1590-1592'de Osmanlıların İspanya'ya karşı donanma sevketme hazırlıkları; 1589-1591'de Osmanlı-Yahudi ilişkilerinde yaşanan kriz; 16. yüzyılın sonlarında Osmanlı merkezî idaresinde yaşanan değişim yani Osmanlı Kızılelması'nın dâhilî ve haricî boyutlarının nasıl olduğuna dair verdiği cevapları bulacaktır.
Magnetic Resonance Imaging of The Pelvis
Magnetic Resonance Imaging of The Pelvis: A Practical Approach presents comprehensive information to deal withcommonly encountered pelvic pathologies. The content is developed by disease-focused experts aiming to share theirexperience to make the information easily applicable to clinical setting and research. The book covers a wide range of pelvic pathologies, and each chapter focuses on problem-solving approaches andincludes tips and advice for multiple real-world scenarios. It also provides comprehensive-yet-tailored protocols, clearguidelines for indications, a detailed discussion of pathologies, descriptions of important differential diagnoses, and pitfalls and their solutions. It is a v...
I nostri modi di raccontare la storia
Prima della recente svolta autoritaria, è stato il golpe militare del 1980 a costituire lo spartiacque che ha mutato il volto della Turchia contemporanea, introducendo una società dei consumi, depoliticizzando le nuove generazioni e smantellando le organizzazioni studentesche e rivoluzionarie attraverso incarcerazioni e torture. Sulla base di una etnografia condotta a Istanbul, il volume esplora la trasmissione intergenerazionale della memoria di violenza politica tra gli ex-militanti degli anni Settanta, le loro famiglie e i giovani attivisti della sinistra turca. Questo percorso diviene l’occasione per ricostruire i mutamenti che hanno portato la Turchia a riscoprire i suoi passati dol...
