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Research Awards Index
  • Language: en
  • Pages: 776

Research Awards Index

  • Type: Book
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  • Published: 1989
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  • Publisher: Unknown

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Current Catalog
  • Language: en
  • Pages: 1144

Current Catalog

  • Type: Book
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  • Published: Unknown
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  • Publisher: Unknown

First multi-year cumulation covers six years: 1965-70.

Molecular and Cellular Biophysics
  • Language: en
  • Pages: 536

Molecular and Cellular Biophysics

Molecular and Cellular Biophysics provides advanced undergraduate and graduate students with a foundation in the basic concepts of biophysics. Students who have taken physical chemistry and calculus courses will find this book an accessible and valuable aid in learning how these concepts can be used in biological research. The text provides a rigorous treatment of the fundamental theories in biophysics and illustrates their application with examples. Conformational transitions of proteins are studied first using thermodynamics, and subsequently with kinetics. Allosteric theory is developed as the synthesis of conformational transitions and association reactions. Basic ideas of thermodynamics and kinetics are applied to topics such as protein folding, enzyme catalysis and ion channel permeation. These concepts are then used as the building blocks in a treatment of membrane excitability. Through these examples, students will gain an understanding of the general importance and broad applicability of biophysical principles to biological problems.

Research Grants
  • Language: en
  • Pages: 1068

Research Grants

  • Type: Book
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  • Published: Unknown
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  • Publisher: Unknown

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Ion Channels
  • Language: en
  • Pages: 944

Ion Channels

Modern applications of electrophysiologica techniques; Expression of ion channels; Expression of ion channels in Xenopus oocytes; Expression of ion channels using other systems; Reconstruction of ion channels in lipid bilayers; Recording of ion channels of cellular organelles and miroorganisms; Data storage and analysis.

Biomedical Index to PHS-supported Research
  • Language: en
  • Pages: 816

Biomedical Index to PHS-supported Research

  • Type: Book
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  • Published: 1990
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  • Publisher: Unknown

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Sigma Receptors
  • Language: en
  • Pages: 416

Sigma Receptors

This book provides an update on sigma receptors, and summarizes recent advances in the medicinal chemistry, molecular biology, and cell biology of sigma receptors. It describes the functional effects mediated by these receptors and the potential clinical implications of these actions. The information is put in a historical perspective. This provides a launching point from which future studies and research directions can easily be developed.

International Review of Neurobiology
  • Language: en
  • Pages: 385

International Review of Neurobiology

Published since 1959, this serial stays up-to-date with current topics in neuroscience; the contributors are first-class experts in their fields. Volume 38 of International Review of Neurobiology presents in-depth reviews on GABAA and other transmitter systems and mechanisms, the genetics of the basal ganglia, the Bergmann glial cell, and the modes of action of monoamines at the cellular level. Neuroscientists will find particularly useful the recent studies on the molecular biology of neurotransmitter transporters.Key Features* Structure, pharmacology, and regulation of GABAA* Bergmann glial cell physiology* Abnormalities of transmitter systems in schizophrenia* Research in genetic influences on the basal ganglia* Presynaptic electrophysiology measurementsMonoamines as stimulators and inhibitors of cellular mechanisms* Molecular biology of neurotransmitter transporters

The Neurobiology of Multiple Sclerosis
  • Language: en
  • Pages: 759

The Neurobiology of Multiple Sclerosis

Multiple sclerosis (MS) is an immune-mediated neurodegenerative disorder of the human central nervous system (CNS) which usually affects young adults with certain genetic backgrounds who are then exposed to certain precipitating environmental antigen(s). Despite major advances of the past two decades in understanding the pathophysiology of MS, and in spite of the introduction of new immunomodulatory and immuno-suppressive agents which may slow down disease progression and delay the onset of disability, the "cause and the "cure for MS remain elusive. This volume of International Review of Neurobiology focuses on MS and related disorders. The volume can be divided into various sections with the main emphasis on MS pathogenesis, clinical features and epidemiology, neuroimaging, and treatment. The ultimate goal of this book is to encourage further research into the pathogenesis of this elusive disease.

National Institutes of Health Research Grants
  • Language: en
  • Pages: 606

National Institutes of Health Research Grants

  • Type: Book
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  • Published: 1990
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  • Publisher: Unknown

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