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The present book has great Mycological significance and will update the knowledge of Resupinate Aphyllophorales of Maharashtra, which presently lacks in the scenario of Indian Mycology. This book will be of immense help for further studies and investiga-tions. Taking into consideration the taxonomic study of Wood Rotting Fungi, this kind of approach is studied for the first time for understanding thoroughly the compilation of the Resupinate Aphyllophorales from a particular region. This book will facilitate further understanding of important pathogens from the vegetation of Maharashtra. The major work deals with the species studied from the family Corticiaceae with non-poroid hymenium; Polyp...
Kidney Cancer: Principles and Practice is a comprehensive and interdisciplinary textbook that encompasses all clinically relevant aspects of the disease. This new edition has been extensively updated and includes brand new material covering the most recent developments in kidney cancer diagnosis and therapy. The user-friendly and clinically oriented content of the book guarantees that it will be of great interest to a wide range of medical professionals, and every effort has been made to ensure that contributions are both easy to understand and directly related to patient care. Content presentation departs from the usual dense chapter format featuring a lengthy series of paragraphs. Instead,...
Despite the efficiency of current cancer treatments, cancer is still a deadly disease for too many. In 2008, 7.6 million people died of cancer; with the current development, it is estimated that the annual cancer death number will grow to 13 million by 2030. There is clearly a need for not only more research but also more innovative and out of the mainstream scientific ideas to discover and develop even better cancer treatments. This book presents the collective works published in the recent Special Issue entitled “Killing Cancer: Discovery and Selection of New Target Molecules”. These articles comprise a selection of studies, ideas, and opinions that aim to facilitate knowledge, thoughts, and discussion about which biological and molecular mechanisms in cancer we should target and how we should target them.
Renal cancer is a health problem of major concern worldwide. Although tyrosine kinase inhibitors and immune check-point blockade treatments, alone or in combination, are giving promising results, failures are quite frequent due to intratumor heterogeneity and to the acquisition of drug resistance. The spectrum of renal cell carcinoma subtypes is wide. Up to 70–80% of renal tumors are clear cell renal cell carcinomas, a clinically aggressive tumor subtype linked to VHL gene inactivation. Next in frequency, the papillary renal cell carcinoma category encompasses an intricate puzzle of classic and newly described entities with poorly defined limits, some of them pending definite clarification...
This book provides a novel exploration of the application of nanofiltration membrane technology for sustainability in various industries, situated in view of recent breakthroughs and the use of reuse, recycle and resource recovery approaches. Moving from a comprehensive discussion of nanofiltration membrane processes to case studies and real-world applications of nanofiltration technology across society, both successes and potential limitations are considered. Features: Detailed discussion of the fundamentals of nanofiltration technology The concepts of reuse, recycle and resource recovery using nanofiltration technology are explored in combination with other technologies to advance circular economy Considered across a range of industries, such as textiles, oil, gas, agriculture and pharmaceutics Written in a thoroughly detailed manner, this book is an essential guide for industry professionals interested in sustainability and working toward a circular economy. Comprehensive discussions of the fundamental processes underpinning nanofiltration technology also make this book particularly appealing to students of industrial chemistry.
The third edition of this critically acclaimed book has updated and expanded the survey of clinical, biological and pathological management of localized and advanced renal cell carcinoma. Internationally renowned editors and contributors explore the latest developments in molecular genetics, focusing on the novel targets that have been discovered in epithelial renal tumors. Comprehensive and authoritative, Renal Cell Carcinoma: Molecular Targets and Clinical Applications, Third Edition is the definitive text on the rapidly evolving landscape of experimental therapeutics, written and edited by leaders of the field.
This book presents the proceedings of the 3rd International Conference on Integrated Petroleum Engineering and Geosciences 2014 (ICIPEG2014). Topics covered on the petroleum engineering side include reservoir modeling and simulation, enhanced oil recovery, unconventional oil and gas reservoirs, production and operation. Similarly geoscience presentations cover diverse areas in geology, geophysics palaeontology and geochemistry. The selected papers focus on current interests in petroleum engineering and geoscience. This book will be a bridge between engineers, geoscientists, academicians and industry.
The complex landscape of breast cancer requires distinct strategies for the management of various molecular subtypes of this disease. Rapid advances in the field of molecular biology have been bewildering for those involved in its study and management. “Molecular Pathology of Breast Cancer” aims to close this knowledge gap by discussing comprehensively the evolution, biological basis and clinical applications with a focus on the “what, when, and how” of the most significant molecular markers known to date. These markers are evaluated in the context of genomic, transcriptomic and proteomic profiles, which is integral to the practice of precision medicine. The application of next gener...
The field of immuno-oncology continues to rapidly evolve as new insights to fight and treat cancer emerge. The fourth edition of Immunotherapy provides the most current overview of immuno-oncology in different cancer types and toxicities associated with immunotherapy. While immunotherapy has revolutionized the treatment landscape of several solid malignancies, several challenges still exist. Only a subset of patients derive clinical benefits; some do not respond at all, and others respond initially, only for their disease to progress later. Because these drugs can activate a broad range of immune cells, patients suffer from a unique set of side effects known as immune-related adverse events....