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Molecular Biology of the Skin
Molecular Biology of the Skin: The Keratinocyte comprehensively reviews the major aspects of keratinocyte and epidermal differentiation, physiology, and pathology, primarily focusing on the molecular aspects. This exciting new resource discusses keratin genes, retinoic acid, and the use of transgenic animals in the study of dermatological pathology. The volume also highlights areas of genetic disease, new animal models to help in understanding dermatological disorders, and gene therapy using skin as a target. W.W. Franke, a pioneer in the study of the molecular biology of keratins, has written the foreword for the book. Molecular Biology of the Skin: The Keratinocyte is intended for use by d...
Arterial Disorders
As our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologic mechanisms of arterial disease is wide ranging, encompassing hemodynamic, metabolic, humoral, inflammatory, genetic and environmental factors. Particular emphasis is placed on recent concepts, such as: the role of age-associated arterial alterations in the initiation and progression of cardiovascular diseases in older persons, the importance of mineral metabolism-bone vascular interactions, the clinical and prognostic significance of the renal resistive index, retinal circulation, toxemia of pregnancy as an arterial disease, and the role of pulmonary/vascular interaction in pulmonary hypertension and cross-talk of macrocirculation and microcirculation in target organ involvement. Evaluation procedures are carefully explained, and the full range of currently available therapeutic options, including lifestyle modifications and pharmacologic approaches, are described and appraised.
Acute Nephrology for the Critical Care Physician
This practical guide provides the reader with answers to important clinically relevant questions regarding the evaluation and management of acute kidney injury (AKI). All aspects of critical care nephrology are covered, from pathophysiology and diagnosis to prevention and treatment. The questions considered relate to a wide range of issues, such as: How do I diagnose AKI? How can I protect the kidney in clinical practice? How do I manage patients with AKI? When should I initiate and how do I perform renal replacement therapy (RTT)? Which type of RTT is most appropriate for my patient? Should I give specific nutrients? In addition to providing practical guidelines and treatment algorithms, th...
Pulmonary Involvement in Patients with Hematological Malignancies
The number of patients treated for hematological malignancies is increasing steadily. To maximize cure rates, aggressive treatments have been introduced, including high-dose chemotherapy, stem cell transplantation, and targeted therapies. As a result, overall and disease-free survival rates have improved substantially, but at the price of life-threatening toxic and infectious complications that chiefly target the lung. This book provides clinicians caring for patients with hematological malignancies with detailed, up-to-date information on all relevant aspects of pulmonary involvement. Individual sections are devoted to epidemiology, diagnostic strategy, lung infections, non-infectious pulmonary involvement, and treatment, including decision making in patients with acute respiratory failure. Each of these sections contains a number of chapters, all written by leading international experts. In addition, the reader’s attention is drawn to important "pearls" relating to each condition.
Annual Update in Intensive Care and Emergency Medicine 2014
The Yearbook compiles the most recent developments in experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
The Obama Presidency
Barack Obama's presidency is a pivotal one in American history, coming at a time of dramatic political change in the United States and amidst an astonishing array of domestic and foreign policy challenges. Not surprisingly, then, the Obama administration has been the focus of intense scrutiny by scholars, the press, and the public, and rarely has the tone of political discourse been more polarized and emotionally charged. In this book a distinguished group of scholars offers an objective and timely examination of the Obama administration; Obama's character, leadership style, and rhetoric; and his domestic, foreign, and national security policies. Engaging, lively, and highly readable, each essay offers important insight into this historic president and presidency.
Media Relations and the Modern First Lady
Media Relations and the Modern First Lady: From Jacqueline Kennedy to Melania Trump examines the communication strategies first ladies and their teams have used to manage press and public interest in their private lives, to promote causes close to their hearts, and to shape their public image. Starting with Jacqueline Kennedy, who was the first to have a staffer with the title “press secretary,” each chapter explores the relationship between a first lady and the media, the role played by her press secretary and communication staff in cultivating this relationship, and the first lady’s media coverage. Contributors exploring the following questions: How effective were the media relations...
Current Catalog
First multi-year cumulation covers six years: 1965-70.
