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While numerous advanced statistical approaches have recently been developed for quantitative trait loci (QTL) mapping, the methods are scattered throughout the literature. Statistical Methods for QTL Mapping brings together many recent statistical techniques that address the data complexity of QTL mapping. After introducing basic genetics topics and statistical principles, the author discusses the principles of quantitative genetics, general statistical issues of QTL mapping, commonly used one-dimensional QTL mapping approaches, and multiple interval mapping methods. He then explains how to use a feature selection approach to tackle a QTL mapping problem with dense markers. The book also pro...
This volume contains papers presented at the 11th scientific meeting of the IFIP working group on reliability and optimization of structural systems. The purpose of Working Group 7.5 is to promote modern structural system reliability and optimization theory and its applications; stimulate research, development, and application; assist and advance research and development; further the dissemination and exchange of information; and encourage education. The main themes include structural reliability methods and applications, engineering risk analysis and decision-making, new optimization techniques and various applications in civil engineering.
This collection appearing for the first time as a paperback, covers the whole field of English comic verse, including nonsense, parody and comic satire, but excluding what is usually called "light verse" of vers de societe.
Walter Charleton (1619-1707) has been widely depicted as a natural philosopher whose intellectual career mirrored the intellectual ferment of the ‘scientific revolution’. Instead of viewing him as a barometer of intellectual change, I examine the previously unexplored question of his identity as a physician. Examining three of his vernacular medical texts, this volume considers Charleton’s thoughts on anatomy, physiology and the methods by which he sought to understand the invisible processes of the body. Although involved in many empirical investigations within the Royal Society, he did not give epistemic primacy to experimental findings, nor did he deliberately identify himself with ...
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In Joyces Mistakes, Tim Conley explores the question of what constitutes an 'error' in a work of art. Using the works of James Joyce, particularly Ulysses and Finnegans Wake, as central exploratory fields, Conley argues that an 'aesthetic of error' permeates Joyce's literary productions.
This second edition of The Cambridge Companion to Joyce contains several revised essays, reflecting increasing emphasis on Joyce's politics, a fresh sense of the importance of his engagement with Ireland, and the changes wrought by gender studies on criticism of his work. This Companion gathers an international team of leading scholars who shed light on Joyce's work and life. The contributions are informative, stimulating and full of rich and accessible insights which will provoke thought and discussion in and out of the classroom. The Companion's reading lists and extended bibliography offer readers the necessary tools for further informed exploration of Joyce studies. This volume is designed primarily as a students' reference work (although it is organised so that it can also be read from cover to cover), and will deepen and extend the enjoyment and understanding of Joyce for the new reader.