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Neurodevelopmental disabilities are a common problem in child health. This book takes a comprehensive approach to addressing these often challenging clinical diagnoses. In particular, it focuses on the two most common of childhood neurodevelopmental disabilities: global developmental delay and developmental language impairment. It seeks to put forward our present conceptualization of these entities as well as their proper evaluation and assessment and diagnosis from a variety of perspectives. It also provides details on our current understanding of the scientific basis of these disorders and their underlying causes. Issues related to medical management, rehabilitation, and eventual outcomes ...
Neurological disorders in children are common: families want to know what is wrong, why it happened, and whether it will happen again. Management and treatment depend on establishing the diagnosis, which usually requires investigations, but the number of possible neurological investigations is now very large indeed, and uncritical investigations may be seriously misleading and often costly. This book, based on the authors’ vast combined personal experience, gives practical guidance on how to target any specific condition with the minimum of tests. Part 1 is a brief distillation of advice on clinical history and examination, introducing the problems that beset those who deal with neurologic...
This book explores the interrelationship of genetics, the environment, or both, in the causation of three neurodevelopmental disorders: autism/autism spectrum disorder (ASD), fetal alcohol spectrum disorder (FASD), and cerebral palsy (CP). It links common clinical problems in developmental pediatrics and pediatric neurology to current concepts and translational research advances in developmental neurosciences, medical genetics, and related disciplines. The first section of the book provides a comprehensive and up-to-date overview of development of the brain, including topics such as neuronal stem cells, epigenetics, and the influence of the prenatal environment. The next three sections analy...
This handbook synthesizes and integrates the science of internalizing and externalizing childhood disorders with the diagnostic structure of the Diagnostic and Statistical Manual – 5th Edition (DSM-5) of the American Psychiatric Association. It offers a comprehensive overview of DSM-5 disorders in childhood, covering etiology, symptom presentation, assessment methods, diagnostic criteria, and psychotherapeutic and pharmacological approaches to treatment, prognosis, and outcomes. Clinical vignettes and empirical insights illustrate key concepts and diagnostic and treatment issues such as developmental, cultural, gender, and other considerations that may influence diagnosis and case formulat...
Completely updated for its Fourth Edition, this book is the most comprehensive, current review of the molecular and genetic basis of neurologic and psychiatric diseases. More than 120 leading experts provide a fresh, new assessment of recent molecular, genetic, and genomic advances, offer new insights into disease pathogenesis, describe the newest available therapies, and explore promising areas of therapeutic development. This edition features an updated section on psychiatric disease and expanded, updated chapters on human genomics, gene therapy, and ethical issues. Six new chapters cover congenital myasthenic syndromes, hereditary spastic paraplegia, ion channel disorders, the phakomatoses, beta-galactosidase deficiency, and prion diseases. A Neurologic Gene Map describes the chromosome locus of all the genetic diseases and their gene product where known. The fully searchable online text will be available on a companion Website. (www.rosenbergneuroandpsychdisease.com)
The Child: An Encyclopedic Companion offers both parents and professionals access to the best scholarship from all areas of child studies in a remarkable one-volume reference. Bringing together contemporary research on children and childhood from pediatrics, child psychology, childhood studies, education, sociology, history, law, anthropology, and other related areas, The Child contains more than 500 articles—all written by experts in their fields and overseen by a panel of distinguished editors led by anthropologist Richard A. Shweder. Each entry provides a concise and accessible synopsis of the topic at hand. For example, the entry “Adoption” begins with a general definition, followe...
Causation is an aspect of epilepsy neglected in the scientific literature and in the conceptualization of epilepsy at a clinical and experimental level. It was to remedy this deficiency that this book was conceived. The book opens with a draft etiological classification that goes some way to filling the nosological void. The book is divided into four etiological categories: idiopathic, symptomatic, cryptogenic, and provoked epilepsies. Each chapter considers topics in a consistent fashion, dealing with the phenomenon of epilepsy in each etiology, including its epidemiology, clinical features and prognosis, and any specific aspects of treatment. The book is a comprehensive reference work, a catalogue of all important causes of epilepsy, and a clinical tool for all clinicians dealing with patients who have epilepsy. It is aimed at epileptologists and neurologists and provides a distillation of knowledge in a form that is helpful in the clinical setting.
This book offers a radically new and definitive reappraisal of Allied responses to Nazi human experiments and the origins of informed consent. It places the victims and Allied Medical Intelligence officers at centre stage, while providing a full reconstruction of policies on war crimes and trials related to Nazi medical atrocities and genocide.
The history of East Asia can be most productively studied through a transnational, translingual, and transcultural approach to the region. In The Sinosphere and Beyond, twenty-six leading and emerging scholars use such approaches in rich clusters of essays on Historiography, Sino-Japanese Encounters, Law and Justice, Politics, Art, Literature, and Translation. Each essay builds on the legacy of Joshua Fogel, whose scholarship defined the contours of the Sinosphere in the Western world and beyond. The collection will be of interest to scholars and students with specific research concerns within these broader rubrics: from the towering progenitors of Japanese Sinology to gendered, diplomatic, and cultural dimensions of Sino-Japanese encounters; from Sinitic poetry to legal culture and revolutionary life; from art commerce and levels of literary expression to the quandaries of translation. In addition to offering a broad range of case studies, the volume is testimony to the methodological importance of a dynamic intra- and transregional approach for an understanding of the layered history of East Asia.