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Protein Engineering
Protein engineering is the rational modification or redesign of proteins using genetic engineering. Thus, it is now possible to modify enzyme specifics, remodel antibodies, and redesign many multi-domain proteins for therapeutic purposes. While the procedures for the introduction of mutations have become routine, predicting and understanding the effects of these mutations can be complicated. This volume provides a comprehensive guide to the methods used at every stage of the engineering process, from the choice of mutation strategy, through protein stability studies, to critical evaluations of mammalian, yeast, and bacterial host expression systems. Protein Engineering: A Practical Approach is the first practical guide to this fascinating mixture of molecular biology, protein structure analysis, computation, and biochemistry. It combines a thorough theoretical foundation with detailed protocols and will be invaluable to all research workers in the area, from graduate students to senior investigators.
Protein Structure Prediction : A Practical Approach
The three-dimensional structure of proteins is a key factor in their biological activity. There is an increasing need to be able to predict the structure of a protein once its amino-acid sequence is known; this book presents practical methods of achieving that ambitious aim, using the latest computer modelling algorithms. - ;The prediction of the three-dimensional structure of a protein from its sequence is a problem faced by an ever-increasing number of biological scientists as they strive to utilize genetic information. The increasing sizes of the sequence and structural databases, the improvements in computing power, and the deeper understanding of the principles of protein structure have led to major developments in the field in the last few years. This book presents practical computer-based methods using the latest computer modelling algorithms. -
Encountering the Suffering of the Other
"I will give you a new heart and put a new spirit in you; I will remove from you your heart of stone and give you a heart of flesh" (Ezechiel 36:26). This biblical image, particularly significant for Jews, Christians, and Muslims, gives insight into the central issues of this book: how a greater readiness to reconcile can take place among individuals and groups who experience the "suffering of the other," even in the midst of a protracted conflict such as the Israeli-Palestinian one. This book offers a collection of essays written by the team members of a transdisciplinary DFG project between Jena University, Ben Gurion University, Tel Aviv University, and the Wasatia Academic Institute.
Catalog of Copyright Entries, Third Series
The record of each copyright registration listed in the Catalog includes a description of the work copyrighted and data relating to the copyright claim (the name of the copyright claimant as given in the application for registration, the copyright date, the copyright registration number, etc.).
Quentin Tarantino
Not since Martin Scorsese in the mid-1970s has a young American filmmaker made such an instant impact on international cinema as Quentin Tarantino, whose PULP FICTION won the Cannes Film Festival's Grand Prix Award. A manic talker, Tarantino obsesses about American pop culture and his favorite movies and movie makers.
Michigan Ensian
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Advances in Artificial Intelligence
This book constitutes the refereed proceedings of the 11th Biennial Conference of the Canadian Society for Computational Studies of Intelligence, AI 96, held in Toronto, Ontario, Canada, in May 1996. The 35 revised full papers presented in the book were carefully selected by the program committee. Although organized by a national society, AI 96 attracted contributions and participants with a significant geographic diversity. The issues addressed in this volume cover an electic range of current AI topics with a certain emphasis on various aspects of knowledge representation, natural language processing, and learning.
Transdisciplinary Approaches on Reconciliation Research
Reconciliation studies are concerned with the processes of rebuilding and improving damaged relationships after major wrongdoings. They focus on factors such as law, economics, and international relations, as well as on elements such as emotions and ethics, culture and religion, media and education. Reconciliation research therefore requires a transdisciplinary approach, to analyse both the procedures leading to the recognition of truth as well as those in which justice is administered; both the impact of public apologies and cooperation agreements; both the implementation of memory policies and civil society initiatives; both the outcomes of trauma therapy and intergenerational encounter gr...
Gender and Action Films
Focusing on a less acknowledged period in Action Cinema history, Gender and Action Films prioritises female led action movies and champion a more meaningful interaction and representation between the Action genre and contemporary issues of race, sexuality, and gender.
