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This book constitutes the refereed proceedings of the First International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI'98, held in Cambridge, MA, USA, in October 1998. The 134 revised papers presented were carefully selected from a total of 243 submissions. The book is divided into topical sections on surgical planning, surgical navigation and measurements, cardiac image analysis, medical robotic systems, surgical systems and simulators, segmentation, computational neuroanatomy, biomechanics, detection in medical images, data acquisition and processing, neurosurgery and neuroscience, shape analysis, feature extraction, registration, and ultrasound.
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Multiple relationships exist between antimicrobial resistance and bacterial virulence, and the spread of clones combining multiple antibiotic resistance and a high virulence level is an increasing problem. It was previously described how mutation-driven or horizontally acquired resistance mechanisms can also have effects on virulence. It was also reported that mobile genetic elements often carry both resistance determinants and virulence-modulating genes, which favors the co-selection of both traits. In the present volume, we present a collection of articles which document additional aspects of the interactions between antimicrobial resistance and virulence in bacteria, and describe their potential therapeutic consequences.
Knowledge of the three-dimensional structure of a protein is absolutely required for the complete understanding of its function. The spatial orientation of amino acids in the active site of an enzyme demonstrates how substrate specificity is defined, and assists the medicinal chemist in the design of s- cific, tight-binding inhibitors. The shape and contour of a protein surface hints at its interaction with other proteins and with its environment. Structural ana- sis of multiprotein complexes helps to define the role and interaction of each individual component, and can predict the consequences of protein mutation or conditions that promote dissociation and rearrangement of the complex. Dete...
Today, the arsenal of “high-precision” or “targeted” radiotherapy includes a variety of techniques and approaches that, like the pieces of a puzzle, need to be put together to provide the prostate cancer patient with high-level optimized radiation treatment. This book examines in detail the role of these innovative radiation techniques in the management of prostate cancer. In addition, a variety of current controversies regarding treatment are carefully explored, including whether prophylactic treatment of the pelvic lymphatics is essential, the magnitude of the effect of dose escalation, whether a benefit accrues from hypofractionation, and what evidence exists for the superiority of protons or heavy ions. Radiotherapy in Prostate Cancer: Innovative Techniques and Current Controversies is intended for both radiation oncologists and urologists with an interest in the up-to-date capabilities of modern radiation oncology for the treatment of prostate cancer.
This book constitutes the refereed proceedings of the First Joint Conference; Computer Vision, Virtual Reality and Robotics in Medicine, CVRMed, and Medical Robotics and Computer-Assisted Surgery, MRCAS, held in Grenoble, France, in March 1997. The volume presents 76 regular revised papers and 16 clinical papers selected from a total of 161 submitted full papers. The volume offers highly innovative and promising research results in computer-assisted medicine and medical informatics. Among the areas covered are medical imaging, virtual reality, medical robotics, and computer-integrated therapy and surgery. The book is of relevance to clinicians, medical engineers, and computer scientists.
This book provides a thorough exploration of the intersection between gender-based healthcare disparities and the transformative potential of artificial intelligence (AI) and machine learning (ML). It covers a wide range of topics from fundamental concepts to practical applications. Transforming Gender-Based Healthcare with AI and Machine Learning incorporates real-world case studies and success stories to illustrate how AI and ML are actively reshaping gender-based healthcare and offers examples that showcase tangible outcomes and the impact of technology in healthcare settings. The book delves into the ethical considerations surrounding the use of AI and ML in healthcare and addresses issu...
Looks at the effectiveness of the prostatectomy and surveys the latest research in prostate cancer managment.
With ever increasing demands on the constrained resources available for health care services, no one involved in decision making in health care can continue to ignore the economic costs of the services provided or the relative value for money offered by the available treatments. Economic evaluation has therefore become an important and indispensable tool for medical deci sion making, alongside the well-known methods for clinical eval uation. This is also true for cancer, despite the aura of sanctity often of surrounding this dreaded disease and the apparent willingness the general population to spend large sums in this area and do "everything possible" for the patients. In recent years, arti...