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Following injury or disease, neural circuitry can be altered to varying degrees leading to highly individualized characteristics that may or may not resemble original function. In addition, lost or partially damaged circuits and the effects of biological recovery processes coupled with learned compensatory strategies create a new neuroanatomy with capabilities that are often not functional or may interfere with daily life. To date, the majority of approaches used to treat neurological dysfunction have focused on the replacement of lost or damaged function, usually through the suppression of surviving neural activity and the application of mechanical assistive devices. Restorative Neurology o...
Presents new information on the mutual interaction of skeletal muscle fibers and motoneurons at all levels, from the physiological to the molecular. Covers genetic, physiological, and hormonal factors affecting skeletal muscle development, control of acetylcholine receptor gene expression, selection and organization of motoneurons, and remodelling and refinement of synaptic inputs under the influence of muscle-derived growth factors. Also discusses the plasticity of the neuromuscular system during regeneration after injury, and in the modification of muscle properties and movement patterns in disease states by changes in sensory input or by electrical stimulation.
This single volume brings together both theoretical developments in the field of motor control and their translation into such fields as movement disorders, motor rehabilitation, robotics, prosthetics, brain-machine interface, and skill learning. Motor control has established itself as an area of scientific research characterized by a multi-disciplinary approach. Its goal is to promote cooperation and mutual understanding among researchers addressing different aspects of the complex phenomenon of motor coordination. Topics covered include recent theoretical advances from various fields, the neurophysiology of complex natural movements, the equilibrium-point hypothesis, motor learning of skilled behaviors, the effects of age, brain injury, or systemic disorders such as Parkinson's Disease, and brain-computer interfaces. The chapter ‘Encoding Temporal Features of Skilled Movements—What, Whether and How?’ is available open access under a CC BY 4.0 license via link.springer.com.
The Encyclopedia of Movement Disorders is a comprehensive reference work on movement disorders, encompassing a wide variety of topics in neurology, neurosurgery, psychiatry and pharmacology. This compilation will feature more than 300 focused entries, including sections on different disease states, pathophysiology, epidemiology, genetics, clinical presentation, diagnostic tools, as well as discussions on relevant basic science topics. This Encyclopedia is an essential addition to any collection, written to be accessible for both the clinical and non-clinical reader. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made ...
First multi-year cumulation covers six years: 1965-70.