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INTRODUCTION TO CANCER BIOLOGY AND GENETICS
Cancer, a global health crisis, is projected by WHO to cause 10 million deaths by 2020, with a mortality rate of one in six. This has spurred intensive research for innovative treatments. Cancer arises from genetic abnormalities triggering uncontrolled cell division, presenting distinct hallmarks. Both inherited and acquired mutations transform cell behavior, resulting in abnormal growth, reproduction, and death. Environmental toxins and spontaneous mutations contribute to genetic changes, while hereditary factors predispose some individuals. Despite rapid advancements in targeted treatments and immunotherapy, therapy resistance remains a formidable challenge due to the disease's heterogeneity. Understanding cancer biology is crucial for developing effective treatments. This book provides a comprehensive overview, covering basic cell biology, genetics, cancer development mechanisms, immune system involvement, diagnostic methods, treatment modalities, including emerging therapies, and challenges like drug resistance. Geared towards students and researchers in biology, medicine, and oncology, it offers vital insights into combating this complex disease.
Bioreactor Design Concepts for Viral Vaccine Production
Bioreactor Design Concepts for Viral Vaccine Production covers a range of interdisciplinary chapters from the engineering perspective of bioreactor design to the biotechnological perspectives of vector design for vaccine development. The book covers bioreactor concepts such as static systems, single-use systems, stirred tanks, perfusion, wave and packed-beds. It reviews options for efficient and economical production of human vaccines and discusses basic factors relevant for viral antigen production in mammalian cells, avian cells, and insect cells. This book will be a great resource for those interested in implemented novel bioreactor design or experimental schemes towards intensified or/and enhanced vaccine production. - Covers the fundamentals of bioreactor designs - Provides strategies for designing a successful vector-based vaccine - Discusses the applications of biological kinetics, thermodynamics and basic substrate requirements for viral vaccine production
Communication Skills and Personality Development
Personality development is an indispensable tool that helps an individual to flourish personal and professional skills. An extraordinary personality is sophisticated, well dressed and groomed, exuding confidence in speech and interpersonal skills. The factors such as biological characteristics, family and social groups, cultural and social factors contribute towards formation of an individual personality. Good communication is vital to any institution’s successful operation and equally imperative for personality development. The book ‘Communication Skills and Personality Development’ is a thorough attempt to present the aforesaid concepts in a simple, understandable, and student-friendly language to gaze the difficult situations and handle them appropriately. The course on Communication Skills and Personality Development has been recommended by V Deans Committee for B.Sc. (Agri.), B.Sc. (Horti.) and B.Tech. faculties throughout the agricultural universities in India; this book has been administered to cover the entire syllabus of this course. The book is highly recommended as a text book for the under graduate agricultural students.
Biosensors in Agriculture: Recent Trends and Future Perspectives
This book reviews the application of nanosensors in food and agriculture. Nanotechnology has the potential to become transformative technology that will impact almost all sectors. Tools like nanosensors, which detect specific molecular interactions, can be used for on-site, in-situ and online measurements of various parameters in clinical diagnostics, environmental and food monitoring, and quality control. Due to their unprecedented performance and sensitivity, nanobiosensors are gaining importance in precision farming. The book examines the use of nanobiosensors in the monitoring of food additives, toxins and mycotoxins, microbial contamination, food allergens, nutritional constituents, pesticides, environmental parameters, plant diseases and genetically modified organisms. It also discusses the role of biosensors in increasing crop productivity in sustainable agriculture, and nanosensor-based smart delivery systems to optimize the use of natural resources such as water, nutrients and agrochemicals in precision farming.
Modeling and Simulation of Functional Nanomaterials for Forensic Investigation
Nanotechnology continues to contribute to the progress of innovations in the area of forensic science ranging from sensing, DNA monitoring, and counterfeiting to fingerprinting. In recent years, functional nanomaterials are widely applied in nanoscience and forensic investigation. They can be used in future interdisciplinary research by scientists, engineers, and biotechnologists. Modeling and Simulation of Functional Nanomaterials for Forensic Investigation focuses on multiple applications related to forensics and provides information linked with nanoparticles. This book provides nanotechnology results in improving the sensitivity of established forensic techniques. It further focuses on different fabrication and characterization techniques of nanomaterials and relates their characteristics with forensic applications. Covering topics such as explosive detection, nano-forensic testing, and nano-trackers, this premier reference source is a comprehensive resource for material engineers, chemical engineers, nanotechnologists, biotechnologists, forensic scientists, students and educators of higher education, researchers, and academicians.
Biotechnological Advances in Agriculture, Healthcare, Environment and Industry
There has been a surge in critical situations such as malnutrition, agricultural productivity, viral diseases, noncommunicable diseases, antibiotic resistance, and depletion of natural resourcest hreatening human welfare during the last decade. Fortunately, a parallel unprecedented growth and development have also taken place in various biotechnological sectors, giving hope and direction to meet these challenges. This book has been written with a very clear purpose of highlighting the contributions of modern biotechnology in solving emerging problems in various sectors. It has been divided into four major sections: Agricultural Biotechnology, Healthcare Biotechnology, Environmental Biotechno...
Handbook of Oxidative Stress in Cancer: Therapeutic Aspects
This reference book, which is the second volume of Targeting Oxidative Stress in Cancer, explores oxidative stress as the potential therapeutic target for cancer therapy. The initial chapters discuss the molecular mechanisms of oxidative stress and its effects on different signaling pathways. Subsequently, the sections examine the impact of redox signaling on tumor cell proliferation and consider the therapeutic potential of dietary phytochemicals and nutraceuticals in reactive oxygen species (ROS)-induced cancer. In turn, it examines the evidence supporting the use of Vitamin C in cancer management, before presenting various synthetic and natural compounds that have therapeutic implications...
