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Oral Microbial Communities
Understand how the intricacies of multispecies community life are related to human oral health. * Explores the immense opportunities presented by readily accessible, genetically tractable, genome-sequenced oral species that naturally form multispecies communities. * Highlights model systems that study oral bacterial interactions, including biofilm growth using saliva as the source of nutrition. * Emphasizes the use of genomic inquiry to probe the human oral microbiome.
Antibody Fc
Immunoglobulins (Igs, antibodies) are key players in adaptive immunity, and pathways mediated through the effector Fc portion of Ig are instrumental in controlling bacterial infections. Therefore, it is not very surprising that bacterial pathogens and commensals through co-evolution with their hosts have learned many tricks to interfere with Fc effector functions. In this chapter, we describe three principally different bacterial strategies to interfere with immunoglobulins: Specific Ig binding, specific or unspecific Ig protelolysis, and, finally, specific and unspecific hydrolysis of functionally important carbohydrates on the immunoglobulins. Elucidating these bacterial immune evasion mechanism evidences bacteria–host co-evolution and provides insight into fundamental aspects of human adaptive immunity and pathogenesis of infection.
Mucosal Immunology
Mucosal immunology is so important since most infectious agents enter the body through the various mucous membranes, and many common infections take place in or on mucous membranes. Mucosal Immunology, now in its third edition, is the only comprehensive reference covering the basic science and clinical manifestations of mucosal immunology. This book contains new research data, exceptional illustrations, original theory, a new perspective and excellent organization. The most comprehensive text on mucosal immunology from internationally recognized experts in the field Includes exceptional color illustrations, new research data, original theory and information on all mucosal diseases Contains nine new chapters and an expanded appendix
Microbial Growth in Biofilms
This volume and its companion, Volume 337, supplement Volume 310. These volumes provide a contemporary sourcebook for virtually any kind of experimental approach involving biofilms. They cover bioengineering, molecular, genetic, microscopic, chemical, and physical methods.
Oral Tolerance
Oral tolerance is a major immunological property of the gastrointestinal mucosa. It plays a critical role in immune defence by preventing inflammatory and allergic responses to dietary and non pathogenic microbial antigens. The interest in oral tolerance has been renewed in the recent years, due to novel insights on its cellular mechanisms and potential clinical applications in the treatment of autoimmune diseases. Oral Tolerance: Cellular and Molecular Basis, Clinical Aspects, and Therapeutic Potential, has been designed as a concise yet comprehensive overview of the newest fundamental and clinical advances in the field. Based on the outstanding contribution of world experts, this book will...
Bacterial Evasion of Host Immune Responses
Table of contents
Textbook of Periodontology and Oral Implantology - E-Book
Textbook of Periodontology and Oral Implantology - E-Book
Aggregatibacter actinomycetemcomitans—Gram-Negative Bacterial Pathogen
Aggregatibacter actinomycetemcomitans is a well-studied Gram-negative bacterium that can often be found in the oral cavity of young individuals. It has several virulence factors and a large genetic diversity, which results in both harmless and highly virulent genotypes. To determine the virulence potential of the isolated bacteria, genetic profiling is recommended. Advanced knowledge of the virulence mechanisms induced by this bacterium is important for the development of future personalized preventive and treatment strategies. The fifteen papers in this book provide a strong and relevant background that can contribute to the improvement of future diagnosis and research strategies.
