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Anticancer Plants: Mechanisms and Molecular Interactions
This book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in targeted preventive therapies. In addition, it highlights the development of novel anticancer drugs from plant sources using bioinformatics approaches. The compiled chapter data aids readers understanding of issues related to bioavailability, toxic effects and mechanisms of action of phytocompounds, and helps them identify the leads and utilize the...
Salt Stress, Microbes, and Plant Interactions: Mechanisms and Molecular Approaches
This book offers an overview of salt stress, which has a devastating effect on the yields of various agricultural crops around the globe. Excessive salts in soil reduce the availability of water, inhibit metabolic processes, and affect nutrient composition, osmotic balance, and hydraulic conductivity. Plants have developed a number of tolerance mechanisms, such as various compatible solutes, polyamines, reactive oxygen species and antioxidant defense mechanisms, ion transport and compartmentalization of injurious ions. The exploitation of genetic variation, use of plant hormones, mineral nutrients, soil microbe interactions, and other mechanical practices are of prime importance in agriculture, and as such have been the subject of multidisciplinary research. Covering both theoretical and practical aspects, the book provides essential physiological, ecological, biochemical, environmental and molecular information as well as perspectives for future research. It is a valuable resource for students, teachers and researchers and anyone interested in agronomy, ecology, stress physiology, environmental science, crop science and molecular biology.
Anticancer Plants: Natural Products and Biotechnological Implements
This volume provides summarized scientific evidence of the different classes of plant-derived phytocompounds, their sources, chemical structures, anticancer properties, mechanisms of action, methods of extraction, and their applications in cancer therapy. It also discusses endophyte-derived compounds as chemopreventives to treat various cancer types. In addition, it provides detailed information on the enhanced production of therapeutically valuable anticancer metabolites using biotechnological interventions such as plant cell and tissue culture approaches, including in vitro-, hairy root- and cell-suspension culture; and metabolic engineering of biosynthetic pathways. Anticancer Plants: Nat...
Natural Bio-active Compounds
Nature has consistently provided human beings with bioactive compounds that can be used directly as drugs or indirectly as drug leads. Some of the major classes of natural bioactive compounds include phenolics, alkaloids, tannins, saponins, lignin, glycosides, terpenoids, and many more. They possess a broad range of biological activities and are primarily useful in the treatment of various health issues. At the same time, the search for new and novel drugs is never-ending and, despite major advances in synthetic chemistry, nature remains an essential resource for drug discovery. Therefore, more and more researchers are interested in understanding the chemistry, clinical pharmacology, and ben...
Natural Bio-active Compounds
Bioactive compounds produced by natural sources, such as plants, microbes, endophytic fungi, etc., can potentially be applied in various fields, including agriculture, biotechnology and biomedicine. Several bioactive compounds have proved to be invaluable in mediating plant-microbe interactions, and promoting plant growth and development. Due to their numerous health-promoting properties, these compounds have been widely used as a source of medication since ancient times. However, there is an unprecedented need to meet the growing demand for natural bioactive compounds in the flavor and fragrance, food, and pharmaceutical industries. Moreover, discovering new lead molecules from natural sour...
Salt Stress, Microbes, and Plant Interactions: Causes and Solution
This book offers an overview of salt stress, which has a devastating effect on the yields of various agricultural crops around the globe. Excessive salts in soil reduce the availability of water, inhibit metabolic processes, and affect nutrient composition, osmotic balance, and hydraulic conductivity. Plants have developed a number of tolerance mechanisms, such as various compatible solutes, polyamines, reactive oxygen species and antioxidant defense mechanisms, ion transport and compartmentalization of injurious ions. The exploitation of genetic variation, use of plant hormones, mineral nutrients, soil microbe interactions, and other mechanical practices are of prime importance in agriculture, and as such have been the subject of multidisciplinary research. Covering both theoretical and practical aspects, the book provides essential physiological, ecological, biochemical, environmental and molecular information as well as perspectives for future research. It is a valuable resource for students, teachers and researchers and anyone interested in agronomy, ecology, stress physiology, environmental science, crop science and molecular biology.
Plant Growth and Health Promoting Bacteria
To cope with the increasing problems created by agrochemicals such as plant fertilizers, pesticides and other plant protection agents, biological alternatives have been developed over the past years. These include biopesticides, such as bacteria for the control of plant diseases, and biofertilizer to improve crop productivity and quality. Especially plant growth promoting rhizobacteria (PGPR) are as effective as pure chemicals in terms of plant growth enhancement and disease control, in addition to their ability to manage abiotic and other stresses in plants. The various facets of these groups of bacteria are treated in this Microbiology Monograph, with emphasis on their emergence in agriculture. Further topics are Bacillus species that excrete peptides and lipopeptides with antifungal, antibacterial and surfactant activity, plant-bacteria-environment interactions, mineral-nutrient exchange, nitrogen assimilation, biofilm formation and cold-tolerant microorganisms.
Promising Antiviral Herbal and Medicinal Plants
With the prevalence of viral diseases causing significant health challenges and the emergence of highly infectious and difficult-to-treat conditions, such as Ebola, HIV/AIDS, and Hepatitis B, there is a pressing need for effective antiviral treatments. Throughout history, viral infections have caused devastating pandemics, leading to widespread illness and mortality. Notable examples include the Black Death caused by Yersinia pestis and the Spanish flu pandemic of 1918. To address this ongoing threat, exploring the potential of herbal and medicinal plants as a source of antiviral compounds is crucial. Promising Antiviral Herbal and Medicinal Plants provides a comprehensive overview of the la...
Crop Production and Global Environmental Issues
Meeting the world’s food security challenge will require a multi-national, collaborative effort to integrate the best research from science, engineering and socioeconomics so that technological advances can bring benefits where they are most needed. The present book covers the effect of major environmental problems on crop production and how to cope with these issues for sustainable agriculture and improvements of crops. The world’s population is predicted to hit 9.6 Billion by 2050, up from today’s total of nearly 7.3 Billion, and with it food demand is predicted to increase substantially. The post-war ‘second agricultural revolution’ in developed countries, and the ‘green revol...
Essentials of Bioinformatics, Volume III
Bioinformatics is an integrative field of computer science, genetics, genomics, proteomics, and statistics, which has undoubtedly revolutionized the study of biology and medicine in past decades. It mainly assists in modeling, predicting and interpreting large multidimensional biological data by utilizing advanced computational methods. Despite its enormous potential, bioinformatics is not widely integrated into the academic curriculum as most life science students and researchers are still not equipped with the necessary knowledge to take advantage of this powerful tool. Hence, the primary purpose of our book is to supplement this unmet need by providing an easily accessible platform for st...
