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Retinal Pigment Epithelium and Macular Diseases
This book contains the papers presented at the Second International Symposium on Retinal Pigment Epithelium (RPE) and at the Fourth Meeting of the European Macula Group. The following topics are covered: functions of RPE and Bruch's membrane; RPE cells proliferation and transplantation; fundus imaging; choroidal disorders; central serous chorioretinopathy and other maculopathies; age-related macular degeneration; choroidal neovascularization; diabetes and retinal vascular disorders; macular surgery. Retinal Pigment Epithelium and Macular Diseases covers the latest findings in clinical and laboratory research, and includes contributions by the most prominent experts in the field. All those interested in retinal diseases will consider this book to be a valuable reference source.
Frontiers in Radiation Oncology
The mode of action by radiation is postulated to be the production of double strand breaks of DNA. The repair of double strand breaks occurs through non homologous end joining through acetylation of histone proteins by histone acetyltransferases (HATs). The fixation of double strand breaks through HAT inhibitors is a promising application for radiation sensitization in the clinic. P53 is a tumour suppressor gene and its mutation has been implicated in 60% of human cancers. As one of the pivotal anticancer genes, P53 controls the transcription and translation of a series of genes. The kinetics of DNA double strand break generation and their co relation to P53 status, ATM and ARF activation are computed and modelled for understanding the potential of such research.
Operative Techniques in Orthopaedic Surgery
Lavishly illustrated, comprehensive in scope, and easy to use, the second edition of Operative Techniques in Orthopaedic Surgery guides you to mastery of every surgical procedure you’re likely to perform – while also providing a thorough understanding of how to select the best procedure, how to avoid complications, and what outcomes to expect. More than 800 global experts take you step by step through each procedure, and 13,000 full-color intraoperative photographs and drawings clearly demonstrate how to perform the techniques. Extensive use of bulleted points and a highly templated format allow for quick and easy reference across each of the four volumes.
Intramedullary Limb Lengthening
Providing a comprehensive overview of the current orthopedic uses of intramedullary devices, this practical, well-illustrated guide opens with a review of the history of limb lengthening from the early external fixator up to Ilizarov’s monumental discoveries, with a summary of the biology of new bone formation in a widening distraction gap. This is followed by post-Ilizarov developments with external fixators designed to ease application and increase patient tolerance of such devices, as well as a discussion of the intramedullary lengthening devices from the earliest mechanical distractors to the most modern implants, detailing the surgical principles, pre-operative planning and specific o...
Orthofix External Fixation in Trauma and Orthopaedics
Orthofix External Fixation in Trauma and Orthopaedics provides the scientific basis behind the success of the Orthofix system of external fixators, which are now widely used throughout the world. These devices are used in the treatment of serious fractures, limb lengthening and limb reconstruction. This book covers comprehensively the wide range of scenarios in which such devices can be used. Each topic is dealt with by the appropriate international expert in the field. Orthofix External Fixation in Trauma and Orthopaedics should be read by all those involved in elective or traumatic orthopaedics.
Operative Techniques in Orthopaedic Trauma Surgery
Providing full-color, step-by-step explanations of all operative procedures in orthopaedic trauma surgery, this text contains the chapters on trauma from Wiesel's "Operative Techniques in Orthopaedic Surgery." The user-friendly format is ideal for quick preoperative review of the steps of a procedure.
Orthopaedic and Trauma Nursing
Orthopaedic and Trauma Nursing provides practitioners working in orthopaedic and musculoskeletal trauma settings with the essential evidence, guidance and knowledge required to underpin effective practice. This comprehensive and contemporary textbook explores the variety of adult and paediatric clinical settings where orthopaedic and trauma practitioners work, including acute wards, clinics, community hospitals, nursing homes and patients' homes. Divided into 5 sections, this book looks at: key issues in orthopaedic and musculoskeletal trauma care; specialist practice issues; common orthopaedic conditions and their care and management; musculoskeletal trauma care; and care of children and yo...
Children’s Orthopaedics and Fractures
Con?rming the British genetic trait for writing and publishing (as well as acting), two English (Oxford and London) and a Scottish orthopaedic surgeon (Edinburgh) have produced a third edition of their comprehensive text, joined, as in the second edition by an editor from Germany, recognizing its part in the European community. The 62 physician contributors are drawn from pink-colored countries in our childhood geography books—the old British Empire from Australia to Zambia and two from the former colony, the USA. The original purpose of the book was to give residents or registrars an easily accessible and concise description of diseases and conditions encountered in the practice of paedia...
External Fixators of the Foot and Ankle
External fixation has proven a valuable tool in the effort to correct deformities, improve healing of fractures, and improve outcomes of orthopedic surgery. This expertly constructed reference, External Fixators of the Foot and Ankle, explores the ways in which external fixators are used to reduce tissue damage, reduce strain on nerves and vasculature, and improve healing in the surgical treatment of foot and ankle deformities and injuries. Authoritative perspectives from leading orthopedic and podiatric surgeons help to build an understanding and strengthen your technique. The multidisciplinary team approach in treating complex trauma, reconstructive, or diabetic patients is emphasized throughout this textbook. Detailed coverage of the tools of external fixation describes the roles, applications, and limitations of the various rings, rods, wires, pins, and designs used in external fixation. How-to, step-by-step instruction addresses a range of fixation procedures, helping readers understand the relevant anatomy and avoid potential complications. Abundant illustrations highlight the text, providing a surgeon’s eye view of a range of commonly performed procedures.
