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Oogenesis
The oocyte is the largest and most mysterious cell in the body of mammalian organisms. Through its growth and maturation, it reaches extreme levels of specialization, while maintaining at the same time a condition of totipotency. Its unique ability, in co-operation with the spermatozoon, to give rise to a fully developed organism formed from hundreds of different tissues and myriads of individual cells has inspired intellectuals of all ages. Oogenesis finds impetus and purpose in casting scientific perspective towards this unique cell for the benefit of scientists and assisted reproductive technology (ART) specialists. The authors of the chapters are distinguished authorities in their respective areas of competence. From the opening of the book the reader is lead on a fantastic voyage from the formation of the primordial oocyte to the development of the early embryo, passing through crucial processes of oogenesis, such as co-ordination of oocyte and follicle growth, gene expression and organelle reorganization during growth and maturation, epigenetic mechanisms, regulation of meiosis, totipotency, cell polarity, oogenesis in vitro and maternal regulation of early development.
The Slow Moon Climbs
A surprising look at the role of menopause in human history—and why we should change the ways we think about it Are the ways we look at menopause all wrong? Susan Mattern says yes and, in The Slow Moon Climbs, reveals just how wrong we have been. From the rainforests of Paraguay to the streets of Tokyo, Mattern draws on historical, scientific, and cultural research to show how perceptions of menopause developed from prehistory to today. Introducing new ways of understanding life beyond fertility, Mattern examines the fascinating “Grandmother Hypothesis,” looks at agricultural communities where households relied on postreproductive women for the family’s survival, and explores the emergence of menopause as a medical condition in the Western world. The Slow Moon Climbs casts menopause in the positive light it deserves—as an essential juncture and a key factor in human flourishing.
Oocyte Physiology and Development in Domestic Animals
Oocyte Physiology and Development in Domestic Animals reviews the most recent advances in the research of physiological and biochemical mechanisms underlying oocyte growth and development, providing readers with the fundamental understanding of these key processes and summarizing this important field of research. The book covers multiple molecular and physiological mechanisms including initiation of oocyte growth during folliculogenesis and in vitro follicle culture to support oocyte competence, that are critical to health and quality. Physiological process ranging from gene expression to metabolism will be covered with an eye toward using these factors to uncover biomarkers that will further advance the field. In addition, the text looks at the effects of in vitro maturation environments on oocyte quality and developmental outcome.
RNA Therapeutics Part A
RNA Therapeutics, Part A, Volume 203 presents the latest on a new class of medication based on RNA molecules. The book includes timely chapters that focus on An introduction to RNA therapeutics and potentials, The development and technologies of RNA therapeutics, Types of RNA therapeutics, Molecular mechanisms of RNA therapeutics, IT, and AI applications in RNA therapeutics, The application of data sciences and bioinformatics in RNA therapeutics, RNA therapeutics history and future perspectives, Recent applications of RNA therapeutic in clinics, Advantages and disadvantages of RNA therapeutics, RNA therapeutics for neurological disease, RNA therapeutics for metabolic disorders, and RNA therapeutics for metabolic disorders. Discusses the history of RNA therapeutics, along with future perspectives Presents the processes of RNA therapeutical developments Covers recent applications of RNA therapeutics in clinics Provides the advantages and disadvantages of RNA therapeutics
Politics of the Womb
Among life’s choices is to have children or remain childfree. Yet those who want a child and find themselves unable, live through the trauma of ‘infertility’—cruelly attributed as ‘their fault’—to undergo the tribulations of assisted reproductive technology. But how safe is aggressive Ivf, invasive Icsi, exploitative ovarian hyper-stimulation and commercial surrogacy? Politics of the Womb proves that there can be broken babies and breaking mothers; it rips away the romanticism around uterus transplants, warns of genetic theft and ‘designer babies’, and points to the human element being sacrificed, as artificial reproduction uses, reuses and recycles the woman. Pinki Virani combines investigation with analysis to question those who lead the worldwide onslaught on the woman’s womb in the name of babies, and squarely confronts what has become the business of baby-making by a chain of suppliers that manufactures on demand. Written in a manner accessible to all, here finally is a path-breaking book which speaks up, in no uncertain terms, for the right to informed choice on responsible reproduction.
Advances in Integrated Design and Production II
This book reports on innovative concepts and practical solutions at the intersection between engineering design, production and industrial management. It covers cutting-edge design, modeling and control of dynamic and multiphysics systems, knowledge management systems in industry 4.0, cyber-physical production systems, additive and sustainable manufacturing and many other related topics. It also highlights important collaborative works between different countries and between industry and universities. Gathering the proceedings of the 12th International Conference on Integrated Design and Production, CPI 2022, held on May 10-12, 2022, at École Nationale Supérieure d'Arts et Métiers (ENSAM), in Rabat, Morocco, this book gathers carefully peer-reviewed chapters, with extensive information for researchers and professionals in the broad area of engineering design, production and management.
