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The Melanocortin System
In the decade before the publication of this study, melanocortin biology matured. Three additional receptors were discovered, and animal models were established addressing the function of each receptor. Researchers now know that the diverse physiologic responses to melanocortins - including their role in development, weight and endocrine regulation, cortisol production, secretion from exocrine glands, and pigmentation - can be defined in terms of individual receptors. In this text, contributors from the field of evolutionary biology, peptide chemistry, pigmentation biology, neuroscience, endocrinology and genetics provide the reader with a comprehensive review of melanocortin biology. Six areas of active research are addressed: peptide and small molecule chemistry; receptor structure and function; energy homeostasis; pigmentation; adrenocorticol function; and behaviour. There are 56 papers and 20 posters altogether, taken from the Fifth Melanocortin Meeting, held in 2002.
Chemokine Receptors
Chemokines are major mediators of immune cells and are involved in a wide range of proinflammatory human diseases, including rheumatoid arthritis, multiple sclerosis, and organ transplant rejection. It has recently been discovered that their receptors are involved in HIV infection. The characterization of these molecules and their receptors is thus of primary importance in understanding a number of human diseases and infections. This volume and its companion Volume 287 Chemokines provide comprehensive experimental protocols used in this field of research. Key Features * Chemokine receptors * Chemokines in disease * Signal transduction of chemokines
Melanocyte-Stimulating Hormones—Advances in Research and Application: 2012 Edition
Melanocyte-Stimulating Hormones—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Melanocyte-Stimulating Hormones in a compact format. The editors have built Melanocyte-Stimulating Hormones—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Melanocyte-Stimulating Hormones in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Melanocyte-Stimulating Hormones—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
The Melanocortin Receptors
Roger Cone and a distinguished team of expert investigators provide the first major treatment of this critically important receptor family. The book illuminates the structure and function of these receptors through a wide-ranging review of the latest findings concerning the biology, physiology, and pharmacology of their peptide ligands and covers the major melanocortin peptides, Melanocortin-1-Receptors through Melanocortin-5-Receptors. Topics include the characterization of the melanocortin receptors, the biochemical mechanism of receptor action, and receptor function and regulation. Timely and authoritative, The Melanocortin Receptors offers an up-to-date knowledge base on the remarkably complex structure and functions of the melanocortins, a guide that will prove invaluable for today's neuroscientists, endocrinologists, pharmacologists, and other clinical and experimental investigators working in this fast moving field.
Hormones, Homeostasis and the Brain
Hormones, Homeostasis and the Brain
Holland-Frei Cancer Medicine
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Basic Physiology for Anaesthetists
Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource.
The Laboratory Fish
Provides interested readers with a current understanding of the biology of fishes as it relates to their utility in the laboratory.
