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Both butadiene and styrene are produced in high volumes; their combined annual production is 20 million tons. They occur together in many industrial and commercial products, including latexes, polymers, adhesives, and particularly in styrene-butadiene rubber tires. Styrene was classified in 1987 within IARC criteria as 2B (possibly carcinogenic to humans); 1,3-butadiene was placed in class 2A (probably carcinogenic to humans) at the meeting of a working group convened by IARC in 1991. This volume brings together the latest information about the toxic hazards of the two compounds. The focus of research on styrene seems to be its neurotoxicological effects and its potential carcinogenicity. In...