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Mesenchymal Cell Activation by Biomechanical Stimulation and its Clinical Prospects
The electrical response of cells to mechanical stimulus is known as mechanotransduction. This monograph is a summary of the mechanotransduction in musculoskeletal cells responsible for body tissue maintenance, support, cover and movement. While mechanotransduction is similar among these cells, there are also several important differences in mechanical parameters and cellular pathways characteristic to each cell type. Therefore, readers will have the opportunity to update their knowledge about the increasing volume of information on mechanotransduction in these cells gained from current research. The book features a primer on general aspects of cellular biomechanics and the experimental metho...
Biophysical Osteoblast Stimulation for Bone Grafting and Regeneration
This book integrates the current basic and clinical knowledge in the area of biophysical stimulation of osteoblast for in vitro and in vivo live bone generation. This innovative methodology and its applications are presented and discussed in several clinical conditions: treatment of fracture nonunion, spine stabilization, bone replacement after tumor resections, stabilization of failed joint endoprostheses in revision surgery and in treatment of bone loss (osteoporosis and osteopenia). The author analyses different types of biophysical stimulation of osteoblasts for bone regeneration, e.g. mechanical (static and alternating, including distraction osteogenesis), electromagnetic (pulsed, alter...
Hip Surgeries
Hip surgery became a benchmark for large joint surgery development. Surgical techniques for the treatment of degenerative, developmental, and traumatic hip pathologies became a challenge, aiming to restore the patients' ambulation in otherwise disabling pathological conditions of the hip joint. In this book the authors present an overview of the pathological basis of the diseased hip and the currently available surgical solutions that provide long-term relief using a reconstructing surgical approach.The book aims to expose young orthopedic surgeons to exciting and continuously developing information on hip surgery, and experienced colleagues will benefit from concise information that might be beneficial in routine surgical activity.
The Kahans from Baku
The Kahans from Baku is the saga of a Russian Jewish family. Their story provides an insight into the history of Jews in the Imperial Russian economy, especially in the oil industry. The entrepreneur and family patriarch, Chaim Kahan, was a pious and enlightened man and a Zionist. His children followed in his footsteps in business as well as in politics, philanthropy, and love of books. The book takes us through their forced migration in times of war, revolution, and the twentieth century’s totalitarian regimes, telling the story of fortune and misfortune of one cohesive family over four generations through Russia, Germany, Denmark, and France, and finally on to Palestine and the United States of America.
Arthroplasty
New technologies, developments in implant design and advances in surgical technique have improved outcomes after joint replacement and decreased rate of complications. It is not a surprise that the number of arthroplasties increases steadily every year and nowadays more than one million patients undergo the procedure annually worldwide. This book is a sequel of a successful series dedicated to one of the fastest growing fields in orthopedics - arthroplasty. Aiming at dissemination of scientific research this book provides a profound overview of the recent evolution of technology and surgical techniques. New developments of implant design and current treatment strategies have been critically discussed by the contributing authors. The process of improving care for patients and standards of treatment requires straightforward access to up-to-date research and knowledge. The format of the publication allows easy and quick reference to shared ideas and concepts. We hope, that the current book will add significant contribution to the success of this endeavor.
A Social History Database of East European Jewish Deserted Wives, 1851-1900
The Database is a companion volume to The Plight of Jewish Deserted Wives, 18511900 (978-1-78976-168-9). It comprises circa 5000 entries, providing name, date and circumstance, with extensive cross-reference to aid future researchers. Agunot (Agunah, sing., meaning anchored in Hebrew) is a Jewish term describing women who cannot remarry because their husband has disappeared. According to Jewish law (Halacha) a woman can get out of the marriage only if the husband releases her by granting a divorce writ (Get), if he dies, or if his whereabouts is not known. Women whose husbands cannot be located, and who have not been granted a Get, are considered Agunot. The Agunah phenomenon was of major co...
The Art of the Musculoskeletal Physical Exam
This book is an invaluable resource for all those seeking to enhance their proficiency in physical examination. Emphasizing its importance for thorough assessments and accurate diagnoses, it equips practitioners with comprehensive theoretical and practical knowledge. With seven sections devoted to different orthopedic structures, the book meticulously examines their underlying anatomy, pathological conditions, and diagnostic methodologies. Each author presents joint-specific tests, and detailed anatomical insights, enabling accurate assessments and identification of underlying conditions. Written and edited by members of ISAKOS, this collaboration draws upon the expertise of leading international experts. Appealing to a broad readership, it is an invaluable tool for orthopedists, sports medicine physicians, physical therapists, athletic trainers and students.
Mitochondrial Diseases
Mitochondria are crucial organelles for any cell type. Mitochondria take responsibility for not only energy production but also regulation of cell death, also called apoptosis; calcium storage; and heat production. Therefore, mitochondrial disease is implicated in the mode of action of many harmful factors for cells such as drugs and environmental contaminants, dysfunction of the oxygen transport system, malnutrition, intense exercise, and genetic variations. This book presents up-to-date knowledge about mitochondrial disease and its complex relation to some diseases such as cardiac failure, cancer, and Alzheimer's and Parkinson's diseases. This book will, therefore, be essential for readers who are interested in life sciences, especially in medicine.
Rotator Cuff Across the Life Span
This book presents the consensus findings of the ISAKOS Shoulder Committee regarding the treatment options in patients suffering from shoulder pain and reduced function or dead arm syndrome as a consequence of rotator cuff injuries. The aim is twofold: to equip readers with a precise knowledge of the presenting characteristics of these injuries in different age groups and to describe in detail the initial management and surgical and non-surgical approaches, taking into account the age-specific features. Readers will find clear descriptions of all the latest arthroscopic techniques, which allow repair of even the largest tears. The indications for and performance of tendon transfer procedures, biceps tenotomy, tenodesis, hemiarthroplasty, anatomic shoulder arthroplasty, reverse total shoulder arthroplasty, and revision surgery are explained. Helpful guidance is also provided on the use of strategies to promote rotator cuff healing, including stem cell therapy and scaffolds. The authors are leading experts in the field, and the book will be of value for all shoulder surgeons and orthopaedic trainees and consultants, as well as sports medicine specialists.
Recent Advances in Hip and Knee Arthroplasty
The purpose of this book is to offer an exhaustive overview of the recent insights into the state-of-the-art in most performed arthroplasties of large joints of lower extremities. The treatment options in degenerative joint disease have evolved very quickly. Many surgical procedures are quite different today than they were only five years ago. In an effort to be comprehensive, this book addresses hip arthroplasty with special emphasis on evolving minimally invasive surgical techniques. Some challenging topics in hip arthroplasty are covered in an additional section. Particular attention is given to different designs of knee endoprostheses and soft tissue balance. Special situations in knee arthroplasty are covered in a special section. Recent advances in computer technology created the possibility for the routine use of navigation in knee arthroplasty and this remarkable success is covered in depth as well. Each chapter includes current philosophies, techniques, and an extensive review of the literature.
