Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Toxicity Testing in the 21st Century
Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.
Application of Toxicogenomics to Cross-Species Extrapolation
Some of what we know about the health effects of exposure to chemicals from food, drugs, and the environment come from studies of occupational, inadvertent, or accident-related exposures. When there is not enough human data, scientists rely on animal data to assess risk from chemical exposure and make health and safety decisions. However, humans and animals can respond differently to chemicals, including the types of adverse effects experienced and the dosages at which they occur. Scientists in the field of toxicogenomics are using new technologies to study the effects of chemicals. For example, in response to a particular chemical exposure, they can study gene expression ("transcriptomics"), proteins ("proteomics") and metabolites ("metabolomics"), and they can also look at how individual and species differences in the underlying DNA sequence itself can result in different responses to the environment. Based on a workshop held in August 2004, this report explores how toxicogenomics could enhance scientists' ability to make connections between data from experimental animal studies and human health.
Environmental AnalysisThe NEPA Experience
Environmental Analysis reviews information gathered during NEPA assessments, summarizes the state of the art in methods and approaches, and defines future opportunities and new approaches required to link high-quality science to the decision-making process. Individual chapters address the process itself, present examples of recent experience with ecological impact assessment, evaluate social impact assessment and the important role the public must play, discuss the difficult challenge of assessing cumulative effects of multiple impacts, consider the regional and global implications of NEPA, and examine the important role of follow-up studies in the process. The authors of the 59 individual papers comprising this book represent the major sectors that have been key participants in the decision-making process from the beginning. These sectors include academia, national laboratories, federal agencies, state agencies, private industry, and foreign nations. Environmental Analysis will be interesting reading for environmental scientists, engineers, policy makers, and lawyers in government and academia; private consultants; and non-government environmental organizations.
Global Environmental Change
How can we understand and rise to the environmental challenges of global change? One clear answer is to understand the science of global change, not solely in terms of the processes that control changes in climate and the composition of the atmosphere, but in how ecosystems and human society interact with these changes. In the last two decades of the twentieth century, a number of such research effortsâ€"supported by computer and satellite technologyâ€"have been launched. Yet many opportunities for integration remain unexploited, and many fundamental questions remain about the earth's capacity to support a growing human population. This volume encourages a renewed commitment to underst...
Opportunities in Biology
Biology has entered an era in which interdisciplinary cooperation is at an all-time high, practical applications follow basic discoveries more quickly than ever before, and new technologiesâ€"recombinant DNA, scanning tunneling microscopes, and moreâ€"are revolutionizing the way science is conducted. The potential for scientific breakthroughs with significant implications for society has never been greater. Opportunities in Biology reports on the state of the new biology, taking a detailed look at the disciplines of biology; examining the advances made in medicine, agriculture, and other fields; and pointing out promising research opportunities. Authored by an expert panel representing a variety of viewpoints, this volume also offers recommendations on how to meet the infrastructure needsâ€"for funding, effective information systems, and other supportâ€"of future biology research. Exploring what has been accomplished and what is on the horizon, Opportunities in Biology is an indispensable resource for students, teachers, and researchers in all subdisciplines of biology as well as for research administrators and those in funding agencies.
Risk Assessment in the Federal Government
The regulation of potentially hazardous substances has become a controversial issue. This volume evaluates past efforts to develop and use risk assessment guidelines, reviews the experience of regulatory agencies with different administrative arrangements for risk assessment, and evaluates various proposals to modify procedures. The book's conclusions and recommendations can be applied across the entire field of environmental health.
Public Participation in Environmental Assessment and Decision Making
Federal agencies have taken steps to include the public in a wide range of environmental decisions. Although some form of public participation is often required by law, agencies usually have broad discretion about the extent of that involvement. Approaches vary widely, from holding public information-gathering meetings to forming advisory groups to actively including citizens in making and implementing decisions. Proponents of public participation argue that those who must live with the outcome of an environmental decision should have some influence on it. Critics maintain that public participation slows decision making and can lower its quality by including people unfamiliar with the scienc...
Reclaiming the Land
Nearly thirty years after creation of the most advanced and expensive hazardous waste cleanup infrastructure in the world, this book provides a much-needed lens through which the Superfund program should be assessed and reshaped. Focusing on the lessons of adaptive management, it explores new concepts and tools for the cleanup and reuse of contaminated sites, and for dealing with the uncertainty inherent in long-term site stewardship.
Global Change Ecosystems Research
Research Council established the Ecosystems Panel in response to a request from the United States Global Change Research Program (USGCRP). The panel's charge included periodic reviews of the ecosystems aspects of the USGCRP, and this is the first of those reviews. It is based on information provided by the USGCRP, including Our Changing Planet (NSTC 1997 and earlier editions 1); ideas and conversations provided by participants in a workshop held in St. Michaels, Maryland, in July 1998; and the deliberations of the panel. In addition, the panel reviewed the ecosystems chapter of the NRC report Global Environmental Change: Research Pathways for the Next Decade (NRC 1999a, known as the Pathways...
