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Colon Cancer Diagnosis and Therapy
  • Language: en
  • Pages: 459

Colon Cancer Diagnosis and Therapy

Colorectal cancer (CRC) is a major global health challenge as the third leading cause for cancer related mortalities worldwide. Despite advances in therapeutic strategies, the five-year survival rate for CRC patients has remained the same over time due to the fact that patients are often diagnosed in advanced metastatic stages. Drug resistance is another common reason for poor prognosis. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early stage diagnosis. This book is the second of three volumes on recent developments in...

Advances in Cyanobacterial Biology
  • Language: en
  • Pages: 420

Advances in Cyanobacterial Biology

Advances in Cyanobacterial Biology presents the novel, practical, and theoretical aspects of cyanobacteria, providing a better understanding of basic and advanced biotechnological application in the field of sustainable agriculture. Chapters have been designed to deal with the different aspects of cyanobacteria including their role in the evolution of life, cyanobacterial diversity and classification, isolation, and characterization of cyanobacteria through biochemical and molecular approaches, phylogeny and biogeography of cyanobacteria, symbiosis, Cyanobacterial photosynthesis, morphological and physiological adaptation to abiotic stresses, stress-tolerant cyanobacterium, biological nitrog...

Mushrooms: A Wealth of Nutraceuticals and An Agent of Bioremediation
  • Language: en
  • Pages: 185

Mushrooms: A Wealth of Nutraceuticals and An Agent of Bioremediation

Mushrooms: A Wealth of Nutraceuticals and An Agent of Bioremediation informs readers about the growing role of mycotherapy and fungal biotechnology for a sustainable future. It presents reviews of efficient treatment strategies for different diseases with the help of mushrooms and derived nutraceuticals. This book also highlights efficient bioremediation strategies exhibited by common mushrooms. Starting with topics on the nutritional and medicinal values of various edible and non-edible mushrooms, the contributors explore their bioactive components. The book progressively covers the antidiabetic, anticancer and antimcrobial potential of mushrooms. The contents are rounded up by reviews of the application of fungal xylanase enzymes and bioremediation of heavy metals from the environment. This is a comprehensive reference for researchers interested in working in the field of applied mycology for nutraceuticals and environmental bioremediation for pollution control.

Diaspora Literature: Identity Beyond Borders
  • Language: en
  • Pages: 286

Diaspora Literature: Identity Beyond Borders

The book Diaspora Literature: Identity Beyond Borders is a compendium of erudite academic articles depicting the generations of diasporic contemplation and consequences figured out in the literature of this specific theme and motif. The book is an enterprise to portray the displacement, alienation, clashes, assimilation, acculturation, rootlessness, torn identities, quest for identity, crisis of identity, and fusion and conflict between two cultures that have been stringed out in three parts of diasporic concerns—Ecumenical Scenario, Acculturation and Question of Hyphenation in Indian Diaspora and Oscillating State of expatriates and immigrants.

Clinical Applications of Biomolecules in Disease Diagnosis
  • Language: en
  • Pages: 458

Clinical Applications of Biomolecules in Disease Diagnosis

This textbook introduces the clinical applications of biomolecules in disease diagnosis, covering a range of topics in biochemistry. The book discusses carbohydrate and protein metabolism abnormalities, lipid digestion and absorption defects, disorders of purine and pyrimidine metabolism, and the chemistry and biological roles of water- and fat-soluble vitamins. It also covers the roles of different macroelements and essential trace elements in physiological processes and the prevention of chronic diseases. The final chapter focuses on recent developments in our understanding of the role of enzymes in disease development and diagnosis. The book chapter also explores the causes and effects of free radicals in the body, including oxidative stress and diseases such as cardiovascular and neurodegenerative diseases. Finally, the chapter discusses cancer development, causes, diagnosis methods, biomarkers, and current treatments such as targeted drug therapy, chemotherapy, and radiation therapy. This book is a useful resource for undergraduate and postgraduate students, researchers and practitioners in biochemistry, medicine, and health sciences.

Transcription and Translation in Health and Disease
  • Language: en
  • Pages: 418

Transcription and Translation in Health and Disease

  • Type: Book
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  • Published: 2023-01-30
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  • Publisher: Elsevier

Transcription and Translation in Health and Disease provides a detailed overview of the regulators underlying transcription and translation in relation to a variety of human diseases and disorders. Beginning with an introduction into the current perspectives relating to these processes in human disease, the book expands to focus on specific mechanisms underlying conditions such as arthritis, cancer, neurological disorders, diabetes and cardiovascular disease. This book considers RNA processing and related mechanisms in eukaryotes including RNA splicing, RNA binding proteins, RNA interference, microRNAs, RNA editing, transcription factors, RNAi screening, CRISPR activation, CRISPR-Cas9 interf...

Obesity and Cancer
  • Language: en
  • Pages: 363

Obesity and Cancer

This book highlights the concordance between signaling pathways that are involved in obesity and cancer cross-talks. It describes the role of cytokines, chemokines, growth factors, insulin, and adipokines in the development of obesity-associated cancers. The book reviews the role of inflammatory signaling pathways such as estrogen-mediated signaling, mTOR and AMP-activated protein kinase pathway and the involvement of adaptive and innate immunity, oxidative stress, gene polymorphism, dietary phytochemicals, and miRNAs in obesity and cancer. In addition, it covers the latest research on the drugs and natural therapeutic agents that target obesity-induced cancers and discusses various in vivo models for studying obesity and obesity-associated cancer. Lastly, it analyses the role of genetic polymorphisms in the obesity-related genes that influence cancer development. The book is a useful resource for researchers in the field of cancer, pharmacology, food chemistry, and clinical biochemistry.

Advances in Cognitive Science and Communications
  • Language: en
  • Pages: 1152

Advances in Cognitive Science and Communications

This book includes selected peer reviewed articles from The 5th International Conference on Communications and Cyber-Physical Engineering (ICCCE 2022), held on 29th and 30th April 2022 in Hyderabad, India. Articles presented here relate to next generation cognitive systems, neuroscience, cyber physical systems and their impact on communication technologies. The book includes content related to cognitive disorders, computational intelligence, fuzzy logics, evolutionary computing that are important for deriving a roadmap for future research on cognitive science/systems and communications. ICCCE is one of the most prestigious conferences conceptualized in the transdisciplinary field of cognitiv...

Coronavirus Therapeutics – Volume II
  • Language: en
  • Pages: 242

Coronavirus Therapeutics – Volume II

The book Coronavirus Therapeutics Volume II provides the most comprehensive review on contemporary knowledge on the consequences during the outbreak of Coronavirus. This also describes the clinical features, diagnostic evaluation and management of Coronavirus patients. Using an integrative approach to the understanding of paradigm gap in host-pathogen interaction studies to the management of Coronavirus patients in the Intensive Care Unit to the current challenges for the effective management of Coronavirus pandemic risk factors including diabetes, hypertension, obesity and repercussion on the central and peripheral nervous system. Key basic and clinical research laboratories from major univ...

Phyto and Rhizo Remediation
  • Language: en
  • Pages: 318

Phyto and Rhizo Remediation

The increasing human population and the associated activities have negatively influenced the ecosystems and life on earth. The continuous addition of agrochemicals, heavy metals and industrial wastes/ effluents in the ecosystems have caused great harm, including loss of productivity, biodiversity, climate change and diseases in plants, animals and humans, resulting in increased marginal lands and endangered sustainability of life on earth. Hence, there is an urgent need to reverse the impact of dangerous pollutants through a holistic, sustainable and biotic approach. Bioremediation involves the utilization of biological systems, mainly plants (phytoremediation) or microorganisms or both in c...