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Tools and techniques for biological inference problems at scales ranging from genome-wide to pathway-specific. Computational systems biology unifies the mechanistic approach of systems biology with the data-driven approach of computational biology. Computational systems biology aims to develop algorithms that uncover the structure and parameterization of the underlying mechanistic model--in other words, to answer specific questions about the underlying mechanisms of a biological system--in a process that can be thought of as learning or inference. This volume offers state-of-the-art perspectives from computational biology, statistics, modeling, and machine learning on new methodologies for l...
This monograph reviews different methods to design or learn valid kernel functions for multiple outputs, paying particular attention to the connection between probabilistic and regularization methods.
‘The clarity, authority, wit and insight Lawrence brings to bear are like torches shining into the turbulent darkness of a subject we all wonder at, but which we mostly feel unable to even to think or talk about with any confidence. Hugely recommended’ Stephen Fry What does Artificial Intelligence mean for our identity? Our fascination with AI stems from the perceived uniqueness of human intelligence. We believe it's what differentiates us. Fears of AI not only concern how it invades our digital lives, but also the implied threat of an intelligence that displaces us from our position at the centre of the world. Neil D. Lawrence's visionary book shows why these fears may be misplaced. Ato...
A renowned computer scientist seeks the unique human quality that will prevail against artificial intelligence. The greatest fear of AI is not that it rules out digital lives but that it displaces human intelligence entirely. If artificial intelligence takes over decision-making what, then, is unique and irreplaceable about human intelligence? The Atomic Human is a journey of discovery to the core of what it is to be human, in search of the qualities that cannot be replaced by the machine. Neil Lawrence brings a timely, fresh perspective to this new, emerging era, recounting his personal journey to understand the riddle of intelligence. By understanding the essential element of what makes us...
The first unified treatment of time series modelling techniques spanning machine learning, statistics, engineering and computer science.
A comprehensive and self-contained introduction to Gaussian processes, which provide a principled, practical, probabilistic approach to learning in kernel machines. Gaussian processes (GPs) provide a principled, practical, probabilistic approach to learning in kernel machines. GPs have received increased attention in the machine-learning community over the past decade, and this book provides a long-needed systematic and unified treatment of theoretical and practical aspects of GPs in machine learning. The treatment is comprehensive and self-contained, targeted at researchers and students in machine learning and applied statistics. The book deals with the supervised-learning problem for both ...
This collection of original, concise essays by leading international scholars draws closely on the Cambridge Edition of the Letters and Works of D. H. Lawrence to provide up-to-date insights into the key contexts to the author's life, career and legacy. It opens with an overview of Lawrence's life as it is explored in biographies and revealed in his letters and writing, before reassessing his relationship to the contemporary literary marketplace, and his response to - and intervention in - a range of literary/cultural and social/historical contexts. It ends with sections on Lawrence's changing critical reception and his powerful legacy in the work of later authors and filmmakers. The essays present a detailed and nuanced picture of Lawrence as an enterprising professional author with a truly cosmopolitan outlook who engaged deeply and strongly with his contemporary culture, and with currents of thought across a range of disciplines.
This selection of key extracts from novels, short stories and poems aims to chart Lawrence's "savage pilgrimage" to that last uncharted territory, "the heart of man". The illustrations include paintings and drawings by Lawrence himself.
A wealth of new research and thinking on Lawrence, the Arab Revolt, and World War One in the Middle East, providing essential background to today's violent conflicts Rarely is a book published that revises our understanding of an entire world region and the history that has defined it. This groundbreaking volume makes just such a contribution. Neil Faulkner draws on ten years of field research to offer the first truly multidisciplinary history of the conflicts that raged in Sinai, Arabia, Palestine, and Syria during the First World War. In Lawrence of Arabia's War, the author rewrites the history of T. E. Lawrence's legendary military campaigns in the context of the Arab Revolt. He explores the intersections among the declining Ottoman Empire, the Bedouin tribes, nascent Arab nationalism, and Western imperial ambition. The book provides a new analysis of Ottoman resilience in the face of modern industrialized warfare, and it assesses the relative weight of conventional operations in Palestine and irregular warfare in Syria. Faulkner thus reassesses the historic roots of today's divided, fractious, war-torn Middle East.
On 28th September 1985, Lee Lawrence's mother Cherry Groce was wrongly shot by police during a raid on her Brixton home. The bullet shattered her spine and she never walked again. In the chaos that followed, 11-year-old Lee watched in horror as the News falsely pronounced his mother dead. In Brixton, already a powder keg because of the deep racism that the community was experiencing, it was the spark needed to trigger two days of rioting that saw buildings brought down by petrol bombs, cars torched and shops looted. The Louder I Will Sing is a powerful, compelling and uplifting memoir about growing up in modern Britain as a young Black man. It's a story both of people and politics, of the underlying racism beneath many of our most important institutions, but also the positive power that hope, faith and love can bring in response.