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Contemporary views on the structure and function of chromatin are presented and the history of the development of these ideas as well as the nature of the nucleic acid and protein components of chromatin are reviewed. The structure of chromatin is studied at several levels, and its modes of transcription and replication are analyzed. Chromatin provides researchers with a critical evaluation of current knowledge. It combines much information that has never before been assembled, and evaluates and interrelates it in a critical way. This has not been done before so that readers are not only provided with an overview, but with extensive references to the literature (there are about 2000 references in all).
Statistics provides tools and strategies for the analysis of data. While much has been written about the methodology, sometimes without reference to data, little has been said about the data. In this volume we present sets of data obtained from many situations without any direct reference to a particular type of analysis. Our view of the usefulness of bringing together a broad collection of sets of data has been shared by many friends and contributors. Students of statistics need to gain facility with their art by applying their knowledge to many sets of data. Textbook examples tend to be small and selected primarily to illustrate a particular technique, thus failing to demonstrate the quest...
Simultaneous Statistical Inference, which was published originally in 1966 by McGraw-Hill Book Company, went out of print in 1973. Since then, it has been available from University Microfilms International in xerox form. With this new edition Springer-Verlag has republished the original edition along with my review article on multiple comparisons from the December 1977 issue of the Journal of the American Statistical Association. This review article covered developments in the field from 1966 through 1976. A few minor typographical errors in the original edition have been corrected in this new edition. A new table of critical points for the studentized maximum modulus is included in this sec...
Orthogonal arrays have played a vital role in improving the quality of products manufactured throughout the world. This first book on the subject since its introduction more than fifty years ago serves as a key resource to this area of designing experiments. Most of the arrays obtained by the methods in this book are available electronically. Anyone running experiments - whether in a chemistry lab or a manufacturing plant, or in agricultural or medical research - will find this book useful.
During the past decade there has been an explosion in computation and information technology. With it have come vast amounts of data in a variety of fields such as medicine, biology, finance, and marketing. The challenge of understanding these data has led to the development of new tools in the field of statistics, and spawned new areas such as data mining, machine learning, and bioinformatics. Many of these tools have common underpinnings but are often expressed with different terminology. This book describes the important ideas in these areas in a common conceptual framework. While the approach is statistical, the emphasis is on concepts rather than mathematics. Many examples are given, wi...
Provides both rich theory and powerful applications Figures are accompanied by code required to produce them Full color figures
Optimization is an important tool used in decision science and for the analysis of physical systems used in engineering. One can trace its roots to the Calculus of Variations and the work of Euler and Lagrange. This natural and reasonable approach to mathematical programming covers numerical methods for finite-dimensional optimization problems. It begins with very simple ideas progressing through more complicated concepts, concentrating on methods for both unconstrained and constrained optimization.
Hope has been called the "life blood of the soul", an indispensable condition for human existence. Yet evidence in this book suggests that hope is neither a necessary nor a universal part of life. Rather, hope is constituted in accordance with cultural norms, and hence it may vary fundamentally from one society to another. In the first of four studies, Averill, Catlin, and Chon delineate four classes of rules that help constitute hope in Western societies. A second study examines the similarities and differences between hope and other, more prototypic emotions, such as anger and love. The third study uses content analyses of maxims and metaphors to clarify further the Western model of hope. ...
Percolation theory is the study of an idealized random medium in two or more dimensions. The emphasis of this book is upon core mathematical material and the presentation of the shortest and most accessible proofs. Much new material appears in this second edition including dynamic and static renormalization, strict inequalities between critical points, a sketch of the lace expansion, and several essays on related fields and applications.
Ignorance and Uncertainty overviews a variety of approaches to the problem of indeterminacies in human thought and behavior. This book examines, in depth, trends in the psychology of judgment and decision-making under uncertainty or ignorance. Research from the fields of cognitive psychology, social psychology, organizational studies, sociology, and social anthroplogy are reviewed here in anticipation of what Dr. Smithson characterizes as the beginning of a "creative dialogue between these researchers". Ignorance and Uncertainty offers the conceptual framework for understanding the paradigms associated with current research. It discusses the ways in which attitudes toward ignorance and uncertainty are changing, and addresses issues previously ignored.