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Combinatorial Chemistry
Combinatorial chemistry, by accelerating the process of chemical synthesis, is having a profound effect on all branches of chemistry, but especially on drug discovery. This informative text explains the origins of combinatorial chemistry and puts the many diverse library methods into context.It explains why some techniques are generally applicable and others are for specialists only. It also focuses on the renaissance of solid phase chemistry and describes the range of available reactions. This is the first single author book in this important, growing field and it describes thebeneficial impact of combinatorial chemistry, especially for the discovery and optimisation of biologically active molecules. This concise and comprehensive overview of combinatorial techniques is an essential text for final year undergraduates, postgraduates, academics and industrialists inchemistry, bio-orgainc chemistry, medicinal chemistry and drug discovery. It provides an accessible introduction to the area for those new to these methods and a valuable reference text to those experienced in this field.
Practical Medicinal Chemistry with Macrocycles
Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations
Using the Pharmaceutical Literature
Gathering information of critical importance for professionals in the pharmaceutical and medical device industries, this guide provides a comprehensive overview of key resources, such as databases, on-line directories, reports, and periodicals-providing at-a-glance guidance and collection development tools for information professionals in this fiel
Laughing Gas, Viagra, and Lipitor
"Jie Jack Li is a medicinal chemist and is intimately involved with drug discovery. Through extensive research and interviews with the inventors of drugs, including those of Viagra and Lipitor, he has assembled an astounding number of facts and anecdotes, as well as much useful information about important drugs we know and use in our lives today. Figures, diagrams, and illustrations highlight the text throughout."--BOOK JACKET.
The Case Against Theism
This monograph offers a critique of arguments for the existence of a specifically Christian God advanced by prominent scholar William Lane Craig. The discussion incorporates philosophical, mathematical, scientific, historical, and sociological approaches. The author does not seek to criticize religion in general, or Christianity specifically. Rather, he examines the modern and relatively sophisticated evidential case for Christian theism. Scholars have been arguing for theism or naturalism for centuries, and there seems little to add to the discussion, especially from the theistic side. However, to assume that either theism or naturalism obtains is a false dichotomy. There are alternatives t...
Chemistry of Drugs
Discusses current research and advances in the field of pharmaceutical chemistry, including drug safety, designer drugs, and the development of new drugs.
Peptides
The Eleventh American Peptide Symposium was held on the San Diego campus of the University of California in picturesque La Jolla on July 9-14, 1989. More than 1100 participants from around the world came to attend a scientific program comprised of an assortment of oral presentations, posters and exhibits. Most rewarding to us was the regular attendance at all the scientific sessions by our registered guests despite the beautiful scenery offered by La Jolla and San Diego county. Indeed for all of us, the purpose of the biennial American Peptide Symposium is to try to keep up with a fast evolving and fascinating field. The goal of the proceedings of these meetings is to provide the scientific ...
