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Una Vida
Neuroscientist Alvaro Cruz finds himself haunted by a recurring dream of a banjo player in an elusive cornfield that leads him on a personal quest to uncover the mysterious past of a New Orleans street singer known as Una Vida. Stricken with Alzheimer's, Una Vida can only offer tantalizing clues about her past through her mesmerizing vocals, incredible recollection of jazz lyrics, and the occasional verbal revisiting of a fascinating life that s fading quickly and forever into the recess of her mind. As Cruz searches for Una Vida's true identity, he learns profound lessons about the human psyche, the nature of memory and himself. Now available in paperback for the first time!
Basic Neurochemistry
Includes bibliographical references and index.
Research Grants
None
Neural Membranes
One of the most active and productive areas of biological science in the past decade has been the study of the biochemical and biophysical prop erties of cell membranes. There is little doubt that membranes are essen tial components of all cellular systems and that each type of membrane manifests specific and characteristic cellular functions. In the nervous system, important events such as neurotransmission, receptor binding, ion transport, axonal transport, and cell uptake are all known to take place within the neural cell membrane. Phospholipids, one of the major components of membranes, not only provide the membrane with its structural integrity and physical proper ties, but also play an...
Neural Membranes
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Membrane Lipid Signaling in Aging and Age-Related Disease
The lipids of cellular membranes not only serve roles in controlling the structure and fluidity of the membrane, but are increasingly recognized for their roles as signalling molecules and modifiers of membrane protein function. Recent studies described in this volume reveal striking changes in membrane lipids during aging and in age-related diseases such as cancer, cardiovascular disease and neurodegenerative disorders. Lipids including inositol phospholipids, cholesterol, sphingolipids and ceramides play important roles in signalling cellular responses to stress and specific stimuli such as growth factors, cytokines and neurotransmitters. One or more of these lipid mediators has been linked to the pathogenesis of age-related diseases. This book provides a comprehensive review of specific membrane lipid mediators and their roles in aging and age-related disease.
Phospholipid Research and the Nervous System
The purpose of this book is to describe the latest findings relating to biochemical and molecular pharmacology of the nervous system and phospholipids and to report the proceedings of the fourth symposium on phospholipids. These Symposia have been satellite meetings of the International Society for Neurochemistry. This meeting was held on May 26-29, 1985 in the Teatro Bibiena in Mantova, Italy. Preceding meetings were held in Cortona, Italy in 1975, in Birmingham, England in 1981, and in British Columbia, Canada in 1983. As was the case for the proceedings of those meetings, this volume presents information that is new and important from the researchers most in volved in advancing our knowle...
Neurobiology of Ischemic Brain Damage
In the eight years since the publication of Volume 63 of Progress in Brain Research, on this subject, developments in the research field have been very fast. For example, receptor physiology and pharmacology is now an intensively studied field, and the excitotoxic hypothesis of cell death is commonly accepted. Furthermore, it is recognized that ischemia and other insults give rise to a sustained depression of overall protein synthesis, yet lead to the expression of dormant genes and to synthesis of new proteins.In view of this development, this volume focusses on the cellular and molecular aspects of ischemic brain damage. The book will be of great value to all those interested in the pathophysiology of ischemic and traumatic brain damage.
Omega-3 Fatty Acids, the Brain and Retina
Research on omega-3 fatty acids has come a long way since its beginnings in the middle 70’s: Starting with studies on the role of omega-3 fatty acids in the secondary prevention of cardiovascular disease, interest soon turned to the mechanisms of and the need to balance the omega-6 to the omega-3 ratio for homeostasis and normal development. Today, it is widely accepted that docosahexaenoic acid (DHA) and arachidonic acid are essential for brain development during pregnancy, lactation and throughout the life cycle. It is also no longer controversial that DHA can affect brain function, mental health and behavior, and studies on supplemental DHA in age-related macular degeneration have revea...
