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Blessed as a Survivor
While Elizabeth Wilms was very young, during World War II, her father was a prisoner of war, and her mother was serving as a slave laborer in the Soviet Union. She and her brother were placed in liquidation camps in Yugoslavia. But her family was blessed; they survived to meet again and later immigrated to the United States. In Blessed as a Survivor, she recounts her life story before and after World War II. Six-year-old Elizabeth was an ethnic German (Danube Swabian) living in the former Yugoslavia when, in the autumn of 1944, the victorious Russian army first arrived, followed by Titos communist partisans, who treated them to a horrific reign of terror. In spring of 1945, Elizabeth and her...
Conflict and Reconciliation
This book deals with one of the main themes in the life and thinking of Nicholas of Cusa (1401-1464), the experience of conflict and the need to realise reconciliation and tolerance. The essays in this volume are discussing not only the various conflicts in which this important philosopher, theologian, mathematician and politician of the 15th century was involved, but also try to interpret the main speculative themes in his philosophical and theological works in the perspective of his historical experiences. As such, the book also delivers a contribution to a better understanding of intellectual, religious and cultural life of the 15th Century as an era of transition between late Middle Ages and Early Modernity. Contributors include: Inigo Bocken, Tilman Borsche, Gerald Christianson, Jean-Michel Counet, Jos Decorte (†), Wilhelm Dupré, Stephan van Erp, Maarten J.F.M. Hoenen, William Hoye, Thomas Izbicki, Frans Maas, Markus Riedenauer, Nikolaus Staubach, and Anton G. Weiler.
Comprehensive Clinical Nephrology - E-Book
Written for fellows, practicing nephrologists, and internists who treat patients with disorders affecting the renal system, Comprehensive Clinical Nephrology, 7th Edition, offers a practical approach to this complex field, supported by underlying scientific facts and pathophysiology. World leaders in nephrology provide current information on clinical procedures and conditions, covering everything from fluid and electrolyte disorders to hypertension, diabetes, dialysis, transplantation, and more—all in a single, convenient volume. - Provides a "just right" amount of basic science and practical clinical guidance to help you make efficient and informed decisions. - Contains new chapters on Bl...
Machine Learning on Commodity Tiny Devices
This book aims at the tiny machine learning (TinyML) software and hardware synergy for edge intelligence applications. It presents on-device learning techniques covering model-level neural network design, algorithm-level training optimization, and hardware-level instruction acceleration. Analyzing the limitations of conventional in-cloud computing would reveal that on-device learning is a promising research direction to meet the requirements of edge intelligence applications. As to the cutting-edge research of TinyML, implementing a high-efficiency learning framework and enabling system-level acceleration is one of the most fundamental issues. This book presents a comprehensive discussion of...
Deciphering the T Cell Response in SARS-CoV-2 Infection
COVID-19 is a recently emerged infectious disease caused by the novel coronavirus SARS-CoV-2. The immune system has a primary role in pathogen elimination and a rapid and effective response can limit disease severity. In this context, T cells play the major role in cell mediated adaptive immune response. The protective role of CD4+ and CD8+ T cells has been inferred from studies on patients who recovered from SARS and MERS and accumulating data are now showing their relevance in SARS-CoV-2 infection. Moreover, memory T cells induced by previous pathogens can shape the susceptibility to, and the clinical severity of other infections, but the complete picture has yet to be elucidated. If the virus is not rapidly eliminated, COVID-19 may progress towards a secondary inflammatory phase that is directly responsible for a worsening in clinical symptoms and immune system impairment. Besides marked lymphopenia, COVID-19 patients’ T cell compartment displays several alterations involving different subpopulations of T cells in terms of phenotype, metabolic profile and functionality.
Clinical Arrhythmology and Electrophysiology E-Book
Part of the renowned Braunwald family of references, Clinical Arrhythmology and Electrophysiology: A Companion to Braunwald's Heart Disease provides today's clinicians with clear, authoritative guidance on every aspect of the latest diagnosis and management options for patients with arrhythmias. This comprehensive reference on cardiac arrhythmias lays a solid foundation of the underlying mechanisms of cardiac electrophysiology with an emphasis on identifying, understanding, and treating individual arrhythmias. Now fully updated from cover to cover, and carefully written to provide continuity and a consistent message throughout, the 4th Edition offers unparalleled coverage of cardiac arrhythm...
Peroxisome Proliferator Activated Receptors: From Basic Science to Clinical Applications
Peroxisome Proliferator Activated Receptors (PPARs) attract great attention in light of the wide spectrum of genes of biological and medical relevance identified as under their control. As a consequence, our knowledge of the role of these receptors in physiology and pathology continues to grow at a fast pace and PPARs have become an interesting target for the treatment of many pathological conditions, including diabetes and atherosclerosis. This volume provides an authoritative view of the current clinical and scientific developments within this evolving area of study.
Diabetes & C-Peptide
In Diabetes & C-Peptide: Scientific and Clinical Aspects, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section provides the background and key features of C-peptide’s physiological function and how its deficiency contributes to complications. The second section describes up-to-date information on the biochemical and molecular actions of C-peptide, including membrane binding, interactions with insulin as well as the interaction between C-peptide and zinc and effects on microvascular vasoreactivity. The third section summarizes in vivo animal studies ...
Platelets, Haemostasis and Inflammation
The book depicts the various roles of platelets in a variety of cardio-metabolic diseases. Traditional and non-traditional platelet functions are described in detail in atherosclerosis, metabolic syndrome, diabetes, myocardial infarction, and other vascular pathologies. Particular focus is put on platelets as a link between haemostasis and inflammation contributing to both. Last but not least the books links the most recent advances in basic sciences with promising novel therapeutic applications and first results of clinical trials. The book is written for biomedical scientists in the sub disciplines vascular biology, biochemistry and immunology; and it as well will be of interest and value for academic physicians like cardiologists, hematologists, general internists and vascular surgeons.
