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WHO Classification of Tumours of the Central Nervous System
WHO Classification of Tumours of the Central Nervous System is the revised fourth edition of the WHO series on histological and genetic typing of human tumors. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. The book, prepared by 122 authors from 19 countries, contains more than 800 color images and tables, and more than 2800 references. This book is in the series commonly referred to as the "Blue Book" series.
The Smartbook of Neurosugery
This book has been done thinking about the most common challenging situations and questions that come during the daily activities as a resident or young neurosurgeon. Introducing The Smartbook of Neurosurgery, is a concise, informative, useful, and evidence-based guide for residents, young neurosurgeons, and health care professionals interested in neurosurgery. - This book has been thought about the most common challenging situations and questions that come during the daily activities as a resident or young neurosurgeon. - This book contains over 2,000 questions divided into 8 chapters and these chapters include basic, translational, clinical, and surgical scenarios - The question and answer...
Brain Tumor
The title of this monograph, Brain Tumor Research and Therapy, is the name of the Conference itself, which had its inaugural meeting in the United States in 1975 andhas since progressed to the international scale. In Japan, the first conference ofits kind was organized by Dr. Takao Hoshino and me and was held at Nikko in 1980, hence its name, the Nikko Conference on Brain Tumor Research and Therapy. Though it started as a small, closed meeting, the conference has grown considerably, and in 1992 it was reorganized as the Japanese Conference on Brain Tumor Research and Therapy and was opened to all neurosurgeons and neuropathologists interested in the study of brain tumor problems and who are participating in this field. The main purpose of the Conference on Brain Tumor Research and Therapy is the candid and informed discussion of the most up-to-date developments in basic re search and clinical treatment of brain tumors. The 3rd Japanese Conference on Brain Tumor Research and Therapy was held at Nasu (Tochigi Prefecture), Japan, in No vember 1994. It was a great honor to welcome many distinguished guests from over seas who kindly attended each session and made valuable contributions.
Pediatric CNS Tumors
Pediatric Oncology - Pediatric CNS Tumors is a detailed review of childhood nervous system tumors with a particular emphasis on biological data and treatment algorithms for each tumor type. Additional detailed information is provided on the recent advances in chemotherapy, radiation and surgery for these tumors. All brain tumors discussed in detail by pathological type Current therapeutic strategies for pediatric brain tumors Includes surgery, chemotherapy, and radiation therapy
Genetic Influences on Neural and Behavioral Functions
Utilizing the flood of information derived from the Human Genome Project and corresponding efforts to elucidate the mouse genome, Genetic Influences on Neural and Behavioral Functions provides a scholarly catalog, organized logically, of relations between the expression of specific genes, nerve cell biology and behavior, normal and abnormal, in animals AND humans. Sample topics include genes in relation to schiziphrenia, panic disorder, epilepsy, alcoholism, sleep, eating disorders, and more.
Tumors of the Central Nervous System, Volume 5
The most recent developments in diagnostic and therapeutic aspects of Gliomas (glioblastoma) in the brain are presented. The importance of personalized medicine and clinical validation for targeted therapy are discussed. The identification of various types of biomarkers (determined by molecular genetics) is included, along with their advantages and limitations as markers in tumor detection and diagnosis. The identification and validation of brain cancer (glioblastoma) genes are discussed. The role of cancer stem cells in the initiation and persistence of malignant gliomas is explained; response of glioblastoma cancer stem cells to various growth factors, such as epidermal growth factor recep...
Surgical Neuropathology of Focal Epilepsies
The need for neuropathology reviews in epilepsy surgery tissues steadily increases. However, textbooks and case presentations highlighting and focusing on this specific topic are rare. The authors of this book reviewed their professional experience in surgical and post-mortem neuropathology studies to compile a coherent summary of: clinico-pathological findings, current classification schemes, useful protocols research data for major histopathological entities of brain lesions encountered in modern epilepsy surgery programs, which is hippocampal sclerosis, brain tumours associated with early epilepsy onset, malformations of cortical development, brain inflammation and malformative vascular lesions. They did not intend to be exhaustive but rather representative of the main lesions and pathologies encountered. Thirty-two illustrated cases constitute the core of this book and will be very helpful in current practice.
Tumors of the Central Nervous System, Volume 8
With tens of thousands of new CNS tumor cases each year in the US alone, this series of publications is a valuable aid to the diagnosis and treatment of these problematic neoplasms. Now, the eighth in the set returns to the topic of brain tumors, dealing with seven distinct types: astrocytoma, medulloblastoma, retinoblastoma, chordoma, craniopharyngioma, oligodendroglioma, and ependymoma. After updating the classification of medulloblastoma the volume provides an overview of ependymoma as well as describing the delineation of prognosis based on the genetic aberrations of the latter patients. The material offers key insights into the molecular pathways involved in tumor biology, such as the r...
Neuro-Oncology of CNS Tumors
Diagnosis and treatment modalities for neuro-oncologic diseases have made considerable advances in recent years. There is hardly a segment of the field of solid tumours that is experiencing such dynamic development with regard to basic scientific findings and clinical results. In the present book the world's leading experts have compiled the current practice-relevant knowledge of neuro-oncologic deseases. The book's clear structure and the uniform presentation of all chapters make this volume a valuable reference, especially for practice-oriented activities, allowing swift access to information about current treatment standards. Hence it will be of great value to both clinicians and researchers.
Role of Signaling Pathways in Brain Tumorigenesis
This book provides acomprehensive overview of cell signalling pathways and morphogens in the genesis of brain tumours. It also explains the role of brain tumour stem cells in the brain tumour progression. It also elucidates the novel early biomarkers that can be utilized to diagnose brain tumours. It presents the basic developmental pathways and morphogens, including retinoic acid and TGF-b that promote brain tumorigenesis. The chapters illustrate the role of stem cells and stem cells mediated cell signalling pathways including, Sonic hedgehog, Notch, Wnt in the brain tumour growth. The chapters also emphasize the role of transcription factors, mainlyNanog, Sox, BMI1, HIF1 and Pax6 in the brain tumouriogensis. It highlights the role of NF-kb, Myc and neurotrophins in the brain tumour development. Finally, the book summarizes the potential early therapeutic targets and targeted drug discovery for brain tumours.
