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Proteomics Sample Preparation
This long-awaited first guide to sample preparation for proteomics studies overcomes a major bottleneck in this fast growing technique within the molecular life sciences. By addressing the topic from three different angles -- sample, method and aim of the study -- this practical reference has something for every proteomics researcher. Following an introduction to the field, the book looks at sample preparation for specific techniques and applications and finishes with a section on the preparation of sample types. For each method described, a summary of the pros and cons is given, as well as step-by-step protocols adaptable to any specific proteome analysis task.
Quantum Bio-informatics V - Proceedings Of The Quantum Bio-informatics 2011
This volume is based on the fifth international conference of quantum bio-informatics held at the QBI Center of Tokyo University of Science.This volume provides a platform to connect mathematics, physics, information and life sciences, and in particular, research for new paradigm for information science and life science on the basis of quantum theory.The following topics are discussed:
The Analysis of Regulatory DNA: Current Developments, Knowledge and Applications Uncovering Gene Regulation
A major goal of integrative research is understanding regulatory networks to such an extent as to allow researchers to model developmental and stress responses. Regulatory networks of living systems include complex and vast interactions between proteins, metabolites, RNA, various signaling molecules and DNA. One aspect of systems biology is understanding the dynamics of protein-DNA interactions affecting gene expression that are caused by transcription factors (TFs) and chromatin remodeling factors. This e-book provides a resource for summarizing current knowledge eukaryotic transcription and explores cis-elements and methods for their analysis, prediction and discovery. The book also presen...
Algorithm Engineering
This book constitutes the refereed proceedings of the Third International Workshop on Algorithm Engineering, WAE'99, held in London, UK in July 1999. The 24 revised full papers presented were carefully reviewed and selected from a total of 46 submissions. The papers present original research results in all aspects of algorithm engineering including implementation, experimental testing, fine-tuning of discrete algorithms, development of repositories of software, methodological issues such as standards for empirical research on algorithms and data structures, and issues in the process of converting user requirements into efficient algorithmic solutions and implementations.
Epistemic Paternalism
This volume considers forms of information manipulation and restriction in contemporary society. It explores whether and when manipulation of the conditions of inquiry without the consent of those manipulated is morally or epistemically justified. The contributors provide a wealth of examples of manipulation, and debate whether epistemic paternalism is distinct from other forms of paternalism debated in political theory. Special attention is given to medical practice, for science communication, and for research in science, technology, and society. Some of the contributors argue that unconsenting interference with people’s ability of inquire is consistent with, and others that it is inconsi...
Data Integration in the Life Sciences
This book constitutes revised selected papers from the 13th International Conference on Data Integration in the Life Sciences, DILS 2018, held in Hannover, Germany, in November 2018. The 5 full, 8 short, 3 poster and 4 demo papers presented in this volume were carefully reviewed and selected from 22 submissions. The papers are organized in topical sections named: big biomedical data integration and management; data exploration in the life sciences; biomedical data analytics; and big biomedical applications.
Challenges of Trustable AI and Added-Value on Health
Artificial Intelligence (AI) in healthcare promises to improve the accuracy of diagnosis and screening, support clinical care, and assist in various public health interventions such as disease surveillance, outbreak response, and health system management. But the increasing importance of AI in healthcare means that trustworthy AI is vital to achieve the beneficial impacts on health anticipated by both health professionals and patients. This book presents the proceedings of the 32nd Medical Informatics Europe Conference (MIE2022), organized by the European Federation for Medical Informatics (EFMI) and held from 27 - 30 May 2022 in Nice, France. The theme of the conference was Challenges of Tr...
Systems Biology and Computational Proteomics
This book constitutes the thoroughly refereed post-proceedings of two joint RECOMB 2006 satellite events: the Second Annual Workshop on Systems Biology, RSB 2006, and the First Biennial Workshop on Computational Proteomics, RCP 2006, held in San Diego, CA, USA in December 2006. The papers cover various aspects of systems biology and explore the use of computational mass spectrometry in various proteomic applications.
Computational Intelligence Methods for Bioinformatics and Biostatistics
Annotation. This book constitutes the thoroughly refereed post-conference proceedings of the Sixth International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2009, held in Genova, Italy, in October 2009. The revised 23 full papers presented were carefully reviewed and selected from 57 submissions. The main goal of the CIBB meetings is to provide a forum open to researchers from different disciplines to present and discuss problems concerning computational techniques in tools for bioinformatics, gene expression analysis and new perspectives in bioinformatics together with 4 special sessions on using game-theoretical tools in bioinformatics, combining Bayesian and machine learning approaches in bioinformatics: state of the art and future perspectives, data clustering and bioinformatics (DCB 2009) and on intelligent systems for medical decisions support (ISMDS 2009).
