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Cellular and Molecular Biology of Intermediate Filaments
Research activity on intermediate filaments (IF) has increased dramatically over the past decade. For the most part, this surge of interest is due to their identification as ubiquitous constituents of the cytoskeleton and karyoskeleton (nuclear matrix) of eukaryotic cells and the fact that we know very little regarding their functions. In sharp contrast to the other major cytoskeletal systems, microfilaments and microtubules, IF exhibit a high degree of heterogeneity with regard to their protein subunit composition. Indeed, one can only marvel at the number of different IF polypeptides, their associated proteins (IFAP) and, consequently, the number of genes involved in encoding the multiple ...
Maradji
Passion et sincérité, valeurs qui m'ont guidé dans ma vie de reporter depuis plus de 50 ans, au service de mes trois illustres Souverains. J'ai vécu une exaltante aventure qui a fait de moi un témoin privilégié, toujours prompt à apporter ma contribution au photo- journalisme marocain. Ce parcours, je le dois aux grands hommes que j'ai eu le privilège de côtoyer. Aussi, je suis heureux de leur rendre dans ce livre un vibrant hommage.
Glioblastoma:
Glioblastoma is the most malignant brain tumor that still remains incurable. It is such a deadly disease that patients do not survive more than a few months after diagnosis. Our understanding of the histopathology and molecular mechanisms of formation of glioblastoma is rapidly advancing so as to provide us clues for devising rational therapeutic strategies for treatment of this malignancy. It is important that we continue to improve our knowledge about the pathogenesis of this devastating disease and explore new areas to find successful therapeutic strategies. Various approaches such as sophisticated imaging techniques, improved surgical procedures, ground-breaking strategies for radiotherapy, chemotherapy, immunotherapy, chemoimmunotherapy, and photodynamic therapy are being used for eradicating glioblastoma. Hopefully, this book will be an important source of information on glioblastoma and therefore be highly useful to the students, postdoctoral fellows, principal investigators, and clinicians involved in this field.
Tumors of the Central Nervous System, Volume 5
The most recent developments in diagnostic and therapeutic aspects of Gliomas (glioblastoma) in the brain are presented. The importance of personalized medicine and clinical validation for targeted therapy are discussed. The identification of various types of biomarkers (determined by molecular genetics) is included, along with their advantages and limitations as markers in tumor detection and diagnosis. The identification and validation of brain cancer (glioblastoma) genes are discussed. The role of cancer stem cells in the initiation and persistence of malignant gliomas is explained; response of glioblastoma cancer stem cells to various growth factors, such as epidermal growth factor recep...
Comoros Customs, Trade Regulations and Procedures Handbook Volume 1 Strategic and Practical Information
2011 Updated Reprint. Updated Annually. Comoros Customs, Trade Regulations and Procedures Handbook
The Molecular and Cellular Biology of Wound Repair
Editing a book of this nature was a simultaneously exhilarating and frightening experience. It was exhilarating to draw from cell biologists, biochemists, and molecular biologists, as well as those dermatologists, pathologists, and pul monologists who are cell biologists at heart, to author chapters. At the same time, it was frightening to ask such busy investigators to devote their precious time to writing chapters that summarize not just their own endeavors but their entire area of expertise. However, the authors assuaged our fears by enthusi astically accepting the proposal to write on specific topics despite the time burden, and to update and willingly accept our editorial comments. In t...
Arab States: Gulf Arab States Cooperation Investment and Business Guide - Strategic Information, Regulations, Developments
Gulf Cooperation Council (GCC) Investment and Business Guide - Strategic and Practical Information
مملكة الخيول
None
Arab States Cooperation and Business Law Handbook Volume 1 Strategic Information and Basic Laws
Arab Cooperation Council Business Law Handbook - Strategic Information and Basic Laws
Biology of Rove Beetles (Staphylinidae)
Rove beetles (Staphylinidae) are common elements of the soil biota, living in the litter and deeper soil layers. Although they are one of the most diverse and speciose groups of insects, no comprehensive books on their general evolution and ecology are as yet available. This book fills that gap, discussing significant aspects and active research examples in the fields of phylogeny and systematics, ecology and conservation, and reproduction and development. The combination of review chapters and case studies provides an excellent introduction to the biology of rove beetles and enables readers to become familiar with active research fields in this megadiverse group of beetles. Offering easy ac...
