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The Primary Care Physician's Guide to Common Psychiatric and Neurologic Problems
This concise volume advises primary care physicians on how to recognize, evaluate, and treat common psychiatric and neurologic complaints in patients with medical illness. Patients with these problems used to be referred to specialists, but under the current system of health care they are increasingly being evaluated and treated by internists and family practitioners. The book contains twelve problem-focused chapters, each written by a specialist faculty member of the Johns Hopkins University School of Medicine who is experienced in consulting with primary care physicians. The problems discussed are sadness, nervousness, forgetfulness, unrealistic concerns about health, suicidal thoughts, alcoholism and drug dependence, weakness, numbness, back pain, headaches, dizziness, and tremor. Screening evaluations for psychiatric and neurologic disorders are also outlined and explained. The book is designed to serve as both an introduction and a convenient reference. The authors emphasize improving communication with patients about issues of diagnosis and treatment.
Human Achondroplasia
Proceedings of the first international symposium held in Rome, Nov. 1986, study the problems of shortness of stature and attempt to find answers to the life-threatening and disabling impairments that affect achondroplasts. Contributions address genetics, ultrastructure, and cartilage histochemistry;
Scientific Directory and Annual Bibliography
Presents the broad outline of NIH organizational structure, theprofessional staff, and their scientific and technical publications covering work done at NIH.
The Least Likely Man
How unassuming government researcher Marshall Nirenberg beat James Watson, Francis Crick, and other world-famous scientists in the race to discover the genetic code. The genetic code is the Rosetta Stone by which we interpret the 3.3 billion letters of human DNA, the alphabet of life, and the discovery of the code has had an immeasurable impact on science and society. In 1968, Marshall Nirenberg, an unassuming government scientist working at the National Institutes of Health, shared the Nobel Prize for cracking the genetic code. He was the least likely man to make such an earth-shaking discovery, and yet he had gotten there before such members of the scientific elite as James Watson and Fran...
The Atlas of Boston History
Few American cities possess a history as long, rich, and fascinating as Boston’s. A site of momentous national political events from the Revolutionary War through the civil rights movement, Boston has also been an influential literary and cultural capital. From ancient glaciers to landmaking schemes and modern infrastructure projects, the city’s terrain has been transformed almost constantly over the centuries. The Atlas of Boston History traces the city’s history and geography from the last ice age to the present with beautifully rendered maps. Edited by historian Nancy S. Seasholes, this landmark volume captures all aspects of Boston’s past in a series of fifty-seven stunning full-...
Imaging in CNS Drug Discovery and Development
Drug development today needs to balance agility, speed, and risk in defining probability of success for molecules, mechanisms, and therapeutic concepts. New techniques such as fMRI promise to be part of a sequence that could transform drug development. Although numerous review articles exist that discuss the use of imaging in drug development, no one source is available that combines the various techniques and includes a discussion of disease mapping. Imaging in CNS Drug Discovery and Development, Implications for Disease and Therapy will serve to distill the most salient developments in the use of imaging in drug development and disease mapping. It will launch evolving concepts that integrate new imaging technologies and paradigms with molecular medicine and molecular profiling ("monics") as well as consider the ethical issues that arise as a result of disease or state diagnosis and the use of imaging in the public eye.
Essentials for Aesthetic Dermatology in Ethnic Skin
This book focuses on creating awareness and detailing the nuances of aesthetic dermatology practice in skin of color. It highlights practical considerations in pre-/intra-/post-procedure care with an emphasis on patient selection for aesthetic procedures and the associated challenges involved in real-time practice. It aims to cater to audiences of countries with both high and low populations of dark-skinned patients, as clinicians often have limited experience in treating this group. Numerous topics are explored through case-based discussions and practical tips. This is a practical ready reference manual for a cosmetic dermatologist dealing with darker skin. Key Features Covers the geo-ethnic skin types of Asians, Southeast Asians, Africans, and Hispanics Explores the topics through case-based discussions Provides comprehensive details about the use of machines on skin of color
Mitochondrial DNA Mutations in Aging, Disease and Cancer
Many human genetic diseases associated with blood, brain, colon, ear, eye, heart, kidney, liver, muscle, and pancreas are caused by mutations in mitochondrial DNA. Mutations in DNA can result in defects of the electron transport complexes, intermediates of the tricarboxylic acid cycle and substrate transport. The clinical manifestation of these diseases often involves muscle and the nervous system. Mitochondrial DNA mutations have now been associated with aging as well as age-related degenerative diseases such as Parkinson's, Alzheimer's, and Huntington's diseases. Changes in structure, function, and a number of mitochondria play an important role in carcinogenesis. Furthermore, the role of mitochondria in the execution of programmed cell death or apoptosis has been recognized recently.
Biomarkers in Brain Disease, Volume 1180
"This volume presents manuscripts stemming from the conference "Biomarkers in Brain Disease" held in Oxford, United Kingdom on January 26-28, 2009."
Neurologic Disease in Women
Although there appears to be a general understanding that the human brain functions similarly in women and in men, an increasing body of knowledge indicates that neuronal connectivity, recruitment, and disease patterns exhibit gender differences. There are clear gender differences in genetic expression, physiologic function, metabolism, hormonal makeup, and psychosocial profile, which often modify the clinical expression of neurologic and other diseases. In addition, ethnic, cultural, and economic factors are frequently overlooked in dealing with health problems of women, even though they undoubtedly have a strong influence on the clinical course of the illness. The second edition of Neurolo...
