You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Rapid advances in molecular biology have accelerated the production of a great number of protein-based therapeutic agents. The major cost in producing these proteins appears to be associated with their purification from the complex mixture of the crude extract. A major challenge to the protein biochemist and the biochemical engineer is the development of rapid, efficient, and cost-effective purification systems. This volume presents state-of-the-art reviews of current methods used in the purifica tion of biological macromolecules that are based on molecular interactions. Thus, the major emphasis is placed on affinity-related techniques. Part I provides a general introduction to affinity chro...
Advances in Pharmacology and Therapeutics II, Volume 2: Neurotransmitters-Receptors is the second of a six-volume compilation of the scientific papers of invited speakers of the Eighth International Congress of Pharmacology. Organized into seven parts, this book begins with an invited lecture on the kinetic analysis of the neuronal and extraneuronal uptake and metabolism of catecholamines. Subsequent parts discuss the regulation of receptor-mediated events; presynaptic receptors in the peripheral and central nervous system; neurotransmitters; and receptor antibodies. The isolated nervous systems in the research of neurotransmission and trophic interactions between nerve and muscle are also discussed.
Fundamentals and Techniques
Annotation. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was...
The authoritative guide on protein purification—now completely updated and revised Since the Second Edition of Protein Purification was published in 1998, the sequencing of the human genome and other developments in bioscience have dramatically changed the landscape of protein research. This new edition addresses these developments, featuring a wealth of new topics and several chapters rewritten from scratch. Leading experts in the field cover all major biochemical separation methods for proteins in use today, providing professionals in biochemistry, organic chemistry, and analytical chemistry with quick access to the latest techniques. Entirely new or thoroughly revised content includes: High-resolution reversed-phase liquid chromatography Electrophoresis in gels Conventional isoelectric focusing in gel slabs and capillaries and immobilized pH gradients Affinity ligands from chemical and biological combinatorial libraries Membrane separations Refolding of inclusion body proteins from E. coli Purification of PEGylated proteins High throughput screening techniques in protein purification The history of protein chromatography
Radiotracer Studies of Interfaces presents a selection of examples illustrating the application of radiotracer studies for different types of interfaces. The value of radiotracer studies in fields such as food chemistry, corrosion of metals, neurochemistry, biology and catalysis is revealed. Separate chapters are devoted to the environmental problems connected with nuclear reactors and with the nuclear industry in general. The book also presents efforts to minimize and avoid the risk of radioactive contamination in the environment by describing new approaches to the problem. Demonstrates the use of radiotracers Contains a detailed discussion of double-layer phenomena Separate chapters are devoted to the most important branches of science where radiotracer study of interfacial phenomena plays an important role
Progress in Medicinal Chemistry
Conteúdo: Hydrolosis: other C-N londs phosphate esters.
Biology of Fertilization, Volume 1: Model Systems and Oogenesis is the first in a three-volume series that gathers various lines of research about reproduction in general and fertilization in particular. Knowledge about cell biology, immunobiology, biochemistry, biophysics, and molecular genetics has progressed significantly beyond our understanding of some aspects of fertilization. Components of these constitute ""model systems."" The present volume includes reviews of such systems, some relatively simple model systems in lower organisms, sex-determining mechanisms, and oogenesis. The book contains 12 chapters organized into two sections. Section I includes studies on evolution, reproductive success, and immortality of the germ line; the structures and mechanisms involved in fertilization problems; and fertilization in Paramecium. Section II on oogenesis includes studies on gamete differentiation; sex-determining role of the H-Y antigen in mammals and non-mammals; the mechanism of starfish oocyte maturation; meiotic arrest in animal oocytes; and the mitotic and meiotic aspects of the mammalian germ cell life cycle.