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In oncology today the accent lies on a multi-disciplinary approach, and consequently this handbook aims to provide wide-ranging information regarding all aspects of the surgical treatment of cancer. It deals with the basic subjects: the biology of cancer, detection and diagnosis, and treatment concepts. From screening to the application of markers, from new transplantation techniques to psychological aspects, an overall picture is presented. The surgeon will find chapters to enhance his knowledge of those areas which may not have required his attention until now. This volume should serve as a valuable reference for many years to come.
Handbook of Thermoplastic Elastomers, Second Edition presents a comprehensive working knowledge of thermoplastic elastomers (TPEs), providing an essential introduction for those learning the basics, but also detailed engineering data and best practice guidance for those already involved in polymerization, processing, and part manufacture. TPEs use short, cost-effective production cycles, with reduced energy consumption compared to other polymers, and are used in a range of industries including automotive, medical, construction and many more. This handbook provides all the practical information engineers need to successfully utilize this material group in their products, as well as the requir...
The European School of Oncology came into existence to respond to a need for information, education and training in the field of the diagnosis and treatment of cancer. There are two main reasons why such an initiative was considered necessary. Firstly, the teaching of oncology requires a rigorously multidiscipli nary approach which is difficult for the Universities to put into practice since their system is mainly disciplinary orientated. Secondly, the rate of technological development that impinges on the diagnosis and treatment of cancer has been so rapid that it is not an easy task for medical faculties to adapt their curricula flexibly. With its residential courses for organ pathologies ...
This book is a comprehensive reference work on the multidisciplinary team (MDT) management of colorectal cancer (CRC) patients that will meet the needs of all members of CRC MDTs and those training in the field. Important, up-to-date knowledge is provided on organization of MDTs, early intervention, surgery, oncology, imaging, pathology, and palliation, with special focus on controversies. This second edition has been thoroughly revised. It includes an entirely new section on the principles of treatment of significant polyps and early cancers and a total of 14 new chapters, including one on the early integration of palliative care. Every effort has been made to ensure that each specialty-specific chapter will be approachable for all team members, thereby facilitating an effective interdisciplinary approach to teamwork. The authors are leading European doctors and scientists who have influenced the development of the MDT concept as well as other aspects of individualized treatment of CRC patients.
Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and methods for testing and clinical trial design are also provided. - One work that can be consulted for all aspects of anticancer drug development - Concise reviews of research fields, combined with practical scientific detail, written by internationally respected experts - A wealth of ideas on current and ...
The recent advances in genomics are continuing to reshape our approach to diagnostics, prognostics and therapeutics in oncologic and other disorders. A paradigm shift in pharmacogenomics and in the diagnosis of genetic inherited diseases and infectious diseases is unfolding as the result of implementation of next generation genomic technologies. With rapidly growing knowledge and applications driving this revolution, along with significant technologic and cost changes, genomic approaches are becoming the primary methods in many laboratories and for many diseases. As a result, a plethora of clinical genomic applications have been implemented in diagnostic pathology laboratories, and the ap...
Bone and soft tissue sarcomas represent only about 2% of all malignancies; however, their treatment – with the goal of curing the patient while preserving the functionality of the affected body part – can, unlike other malignancies, only be successful with therapy concepts devised by interdisciplinary teams. This volume provides an extensive up-to-date overview of the specific diagnostics and current treatment standards of these rare entities, presenting the various limb-sparing modalities for patients with bone and soft tissue sarcomas with special regard to innovative reconstructive options. The evaluation of quality of life based on validated scores and the individual methods of coping with the illness through creative artistic projects are also acknowledged and integrated in the whole concept.
An expert guide to targeting protein kinases in cancer therapy Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication. Complete with full-color presentations, Targeting Protein Kinases for Cancer Therapy defines the structural features of protein kinases and examines their cellular functions. Combining kinase biology with chemistry and pharmacology applications, this book enlists emerging data to drive the discovery of ne...
Advanced magnetic nanostructures is an emerging field in magnetism and nanotechnology, but the literature consists of a rich variety of original papers and parts of reviews and books whose scope is comparatively broad. This calls for a book with specific emphasis on state-of-the-art synthetic methods for fabricating, characterizing and theoretically modeling new magnetic nanostructures. This book is intended to provide a comprehensive overview of the present state of the field. Leading researchers world-wide have contributed a survey of their special ties to guide the reader through the exploding literature in nanomagnetic structures. The focus is on deliberately structured nanomagnets. It includes cluster assembled, self-organized and patterned thin films but excludes, for example, multilayered thin films. We target both industrial and academic researchers in magnetism and related areas, such as nanotechnology, materials science, and theoretical solid-state physics.