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Seldin and Giebisch's The Kidney
A classic nephrology reference for over 25years, Seldin and Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. In this 5th edition, such new and powerful disciplines as genetics and cell biology have been deployed to deepen and widen further the explanatory framework. Not only have previous chapters been extensively updated, but new chapters have been added to incorporate additional disciplines. Individual chapters, for example, now provide detailed treatment of the significance of cilia; the role of stem cells is now given special consideration. Finally, there has been a significant expansion of the section of pathophysiology, incorporating the new...
International Crime in the 20th Century
Between 1919 and 1939, crime received a prominent place on the international public agenda. This book explores the blueprint for twenty-first century international crime prevention - The League of Nations approach - which established institutions for confronting dangerous drugs, traffic in women and terrorist violence.
Breaking the Appalachian Barrier
In 1750 the Appalachian Mountains were a formidable barrier between the British colonies in the east and French territory in the west, passable only on foot or horseback. It took more than a century to break the mountain barrier and open the west to settlement. In 1751 a private Virginia company pioneered a road from Maryland to Ohio, challenging the French and Indians for the Ohio country. Several wars stalled the road, which did not start in earnest until after Ohio became a state in 1803. The stone-paved Cumberland Road--from Cumberland, Maryland, to Wheeling, Virginia--was complete by 1818 and over the next 30 years was traversed by Conestoga wagons and stagecoaches. The Baltimore and Ohio Railroad--the first general purpose railroad in the world--started in Baltimore in the 1820s and reached Wheeling by 1852, uniting east and west.
You Never Forget Your First
Having already penned Getting in the Game, his inside scoop on the mayhem within baseball's winter meetings, Josh Lewin once again gives baseball fans a window into the big leagues. By interviewing big league ballplayers about their first day in the majors, Lewin creates fascinating mini-biographies of the players, highlighting the personalities hidden behind the on-field accomplishments. He lets the players recount their own memories of how they made it to the big leagues. In You Never Forget Your First, Lewin shares the stories of players great and less so. Tony Gwynn recalls singling in his first at bat and finding Pete Rose waiting for him at first base with a wink and a warning: "Don't ...
Aquaporins
Aquaporins summarizes the present knowledge in this expanding field of research, starting with the structural analysis of water channel proteins. Subsequent chapters begin with mammalian aquaporins, examining physiology and pathophysiology, analysis of knock-out model animals, and the regulation of aquaporin function. Also covered is the distribution and regulation of aquaporins in plants and the function of water and glycerol channels in microbial systems. - Comprehensive treatment of a topical research field - Authored by world leaders in the field - Covers structural biology and physiology - Covers different experimental and biological systems - Chapters on plant and microbial systems - Extensive treatment of mammalian physiology and pathophysiology - Structural analysis excellently illustrated
Fetal and Neonatal Physiology
Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. You'll also have easy access to the complete contents and illustrations online at expertconsult.com. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Und...
Molecular Biology and Physiology of Water and Solute Transport
Biophysical studies in the 1950ies and 1960ies led to the realization that the water permeability of certain biological membranes must be due to the presence of water transporting proteins. This hypothesis was confirmed in 1991 and 1992 with the pioneering discovery of the first molecular membrane water channel, CHIP28, by Agre and coworkers. This integral membrane protein, which is abundant in the erythrocyte membrane and in many epithelial cells, is now called aquaporin-1 or AQP1. Thus the terms water channel or aquaporin are synonymous. In July 2000 more than 200 researchers came together in Gothenburg, Sweden, for the `3rd International Conference on the Molecular Biology and Physiology of Water and Solute Transport" to discuss progress in this emerging research field. 58 different presentations from this conference are the basis for this book. Cumulatively, these 58 short chapters provide a balanced overview complementing numerous recent reviews in this field.
Core Concepts in the Disorders of Fluid, Electrolytes and Acid-Base Balance
Fluid, electrolyte, and acid-base disorders are central to the day-to-day practice of almost all areas of patient-centered medicine – both medical and surgical. Virtually every aspect of these disorders has experienced major developments in recent years. Core Concepts in the Disorders of Fluid, Electrolytes and Acid-Base Balance encompasses these new findings in comprehensive reviews of both pathophysiology and clinical management. In addition, this volume offers clinical examples providing step-by-step analysis of the pathophysiology, differential diagnosis, and management of selected clinical problems. Written by leading experts in fluid, electrolyte, and acid-base disorders, this reference is an invaluable resource for both the nephrologist and the non-specialist physician, or medical trainee.
