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Broadening the Genetic Base of Grain Legumes
Grain legumes play significant and diverse role in the farming systems and provide nutrition security to the largely vegetarian and relatively poorer people around the world. These are ideal crops for achieving three simultaneous developmental goals viz. reducing poverty, improving human health and nutrition and enhancing ecosystem resilience. Globally, grain legumes are the second most important crop group next only to cereals but a large proportion of area of it is under rainfed-low input systems as compared to cereals contributing to lower yields. The other important factor responsible for reduced yield in grain legumes is the narrow genetic base of the present day pulse varieties. In ord...
Aquatic Lectins
This book provides the latest information on fish lectins from the perspective of inflammation and presents new ideas on the complicated mechanisms of lectin biochemistry and associated interactions. Key features include discussion of mechanisms recently identified to be involving lectin family types, presentation of the latest evidence regarding the molecular approaches in fish lectins, and thorough explanation of the concept of antimicrobial and immunological roles and current understanding of the significance of its disease resistance related studies. Gene expression studies is another important element of the book, and it is proposed that gene editing technology provides gaining attention in the biological role of fish lectin research. Examples of the many lastest molecular approaches, applications and future perspectives in fish lectin specific topics covered in this book include the information right from the basics to the advancements in this area. The book will be a valuable update and resource for both experienced and younger researchers working in the field of lectins and immunology.
Emerging Drugs and Targets for Multiple Sclerosis
Multiple sclerosis (MS) is a complex disease with a presumed autoimmune aetiology and few current effective treatments. Disease modifying therapies focus on the altering the natural course of relapsing and remitting MS, targeting the inflammatory response. Other targets involve tacking the cause of the disease – demyelination of axons through remyelination therapies. Due to several recent breakthroughs in the understanding of the pathophysiology of MS new targets for remyelination and immunomodulation are rapidly emerging. This book provides a comprehensive overview of drug discovery and development for the molecular basis of the disease, from new targets to drugs currently in clinical development, cellular and animal disease models to biomarkers for diagnosis and assessment in clinical trials. Emerging Drugs and Targets for Multiple Sclerosis is an ideal reference for any student or researcher interested in drug development for neurodegenerative diseases, autoimmune diseases and MS in particular.
The Mungbean Genome
This book reports on the current global status of mungbean and its economic importance. Mungbean (Vigna radiata)—also called green gram—is an important food and cash crop in the rice-based farming systems of South and Southeast Asia, but is also grown in other parts of the world. Its short duration, low input requirement and high global demand make mungbean an ideal rotation crop for smallholder farmers. The book describes mungbean collections maintained by various organizations and their utilization, especially with regard to adapting mungbean to new environments. It provides an overview of the progress made in breeding for tolerance to biotic and abiotic stresses; nutritional quality enhancement including genomics approaches; and outlines future challenges for mungbean cultivation. In addition, genomic approaches to evaluating the evolutionary relationship between Vigna species and addressing questions concerning domestication, adaptation and genotype–phenotype relationships are also discussed
Advances in Nonlinear Dynamics: Methods and Applications
This is the second and final issue of the collection of papers that were contributed by friends and colleagues of (Late) Professor P. R. "Pat" Sethna of the University of Minnesota to commemorate his 70th birthday on May 26, 1993. The first set of contributions was published in Nonlinear Dynamics as the last issue (no. 6) of Vol. 4 in 1993. As circumstances would have it, Professor Sethna was diagnosed with cancer in the fall of 1992 and, after an extended battle with the disease, he passed away on November 4, 1993, just a few days before the first set of contributed papers appeared in print. It is gratifying to report that the organizers of these vi Foreword commemorative issues in Nonlinea...
Advances in Planar Lipid Bilayers and Liposomes
Volume 5 presents recent research on both planar lipid bilayers and liposomes based on their historic and experimental realization. Advances in Planar Lipid Bilayers and Liposomes, Volume 5, continues to include invited chapters on a broad range of topics, covering both main arrangements of the reconstituted system, namely planar lipid bilayers and spherical liposomes. The invited authors present the latest results in this exciting multidisciplinary field of their own research group.Many of the contributors working in both fields over many decades were in close collaboration with the late Prof. H. Ti Tien, the founding editor of this book series. There are also chapters written by some of the younger generation of scientists included in this series. This volume keeps in mind the broader goal with both systems, planar lipid bilayers and spherical liposomes, which is thefurther development of this interdisciplinary field worldwide. * Contributions from newcomers and established and experienced researchers* Exploring theoretically and experimentally the planar lipid bilayer systems and spherical liposomes* This volume is dedicated to mark the Bilayer Lipid Membranes 45th anniversary
Lions 324B2 District Directory 2017-18
District Governor PMJF Lion T A Boobpathi, released the Lions Directory for the year 2017-18 as a Printed Book containing Colourful service activities, Photographs of Club Officials, District Lion Leaders etc. This Digital Edition is a replica of the book, enables portability and read in Mobile Phones.
The Molecular Mechanisms of Regulatory T cell Immunosuppression
Ever since Regulatory T cells (T-Regs) were first defined as peripheral CD4+ T cells that express the interleukin-2 (IL-2) receptor alpha chain (IL-2Ra), there have been intensive efforts to determine the molecular mechanisms whereby this minor subset of CD4+ T cells (~ 5-10%) nonspecifically suppresses all potential effector T cells, whether reactive to self or non-self antigens. Multiple possible molecular mechanisms have been implicated, including the scavenging of IL-2 via the expression of high densities of IL-2Rs, the inhibition of antigen presentation via CTLA-4 molecules leading to decreased IL-2 production, the activation of intracellular cAMP thereby suppressing both IL-2 productio...
