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Genetic Aberrancies and Neurodegenerative Disorders
Genetic Aberrancies and Neurodegenerative Disorders presents critical reviews and emerging findings concerning the roles of genetic mutations and polymorphisms in the pathogenesis of a range of neurological disorders including Alzheimer's and Parkinson's diseases, trinucleotide repeat disorders, stroke, epilepsy and others. This volume, written by leading experts, brings together fundamental information concerning the roles of inherited traits in the pathogenesis of different neurodegenerative disorders. In addition to providing a catalogue of the known genetic alterations that are linked to specific neurodegenerative disorders, the chapters detail the current state of understanding of the c...
Alzheimer's Disease: A Century of Scientific and Clinical Research
This publication is a landmark work commemorating the centennial of Alois Alzheimer's discovery of what would be known as Alzheimer's disease (AD). The centennial of Alois Alzheimer’s original description of the disease that would come to bear his name offers a vantage point from which to commemorate the seminal discoveries in the field. It traces how the true importance of AD as the major cause of late life dementia ultimately came to light and narrates the evolution of the concepts related to AD throughout the years and its recognition as a major public health problem, with an estimated 30-40 million people affected by AD today. To identify the breakthroughs, the editors have used citati...
Rifting and Sediments in the Red Sea and Arabian Gulf Regions
Rifting and Sediments in the Red Sea and Arabian Gulf Regions is a unique text that covers a wide range of topics related to the tectonics and geology of the Red Sea and Arabian (Persian) Gulf region. This book is a collection of invited and peer-reviewed chapters contributed by active researchers around the world. The topics covered in this book include tectonics, magmatism, and lithology, particularly in the Red Sea area. The book also delves into the sediments and evaporites of the Red Sea and Gulf. As the area around the Arabian Peninsula is prone to earthquakes, the seismic hazard estimated in the Red Sea region is also covered by several chapters. Each chapter presents new data and offers extensive lists of references for the reader to explore further. With the ongoing debates regarding the structure of the Red Sea, this book serves as an excellent resource for researchers and any individuals interested in the geology of these two unique seas.
Neurodegeneration and Prion Disease
This is the first and only book on the subject of prions to cover the cause of cell death in the disease. It covers the full range of competing theories on the subject, from broad description and basic points up to the final details of the basic science.
Treatise on Geochemistry
This extensively updated new edition of the widely acclaimed Treatise on Geochemistry has increased its coverage beyond the wide range of geochemical subject areas in the first edition, with five new volumes which include: the history of the atmosphere, geochemistry of mineral deposits, archaeology and anthropology, organic geochemistry and analytical geochemistry. In addition, the original Volume 1 on "Meteorites, Comets, and Planets" was expanded into two separate volumes dealing with meteorites and planets, respectively. These additions increased the number of volumes in the Treatise from 9 to 15 with the index/appendices volume remaining as the last volume (Volume 16). Each of the origin...
Greenfield's Neuropathology - Two Volume Set
Greenfield's Neuropathology, the world’s leading neuropathology reference, provides a comprehensive account of the pathological findings in neurological disease, their biological basis, and their clinical manifestations. The book’s detailed advice on pathological assessment and interpretation is based on clear descriptions of molecular and cellular processes and reactions that are relevant to the development of the nervous system, as well as its normal and abnormal functioning. The information is presented in an accessible way to readers working within a range of disciplines in the clinical neurosciences, and neuropathological findings are placed within the context of a broader diagnosti...
The Mantle and Core
Though largely inaccessible, the geochemistry of Earth's mantle and core can be examined through a wide variety of approaches. Volume 2 focuses first on "remote" sensing using evidence from cosmochemical, seismic, petrologic and geochemical approaches. Mantle composition is then examined in detail through descriptions of mantle samples brought to Earth's surface through tectonic, volcanic, and volatile-outgassing processes. The volume concludes with examination of processes that modify the composition of the mantle and core including an early magma ocean, partial melting, element partitioning between minerals and melts, and physical mixing caused by plate subduction, mantle convection and mass exchange between mantle and core. Reprinted individual volume from the acclaimed Treatise on Geochemistry, (10 Volume Set, ISBN 0-08-043751-6, published in 2003) - Comprehensive and authoritative scope and focus - Reviews from renowned scientists across a range of subjects, providing both overviews and new data, supplemented by extensive bibliographies - Extensive illustrations and examples from the field
Prion Diseases
The overwhelming interest and the participation of more than 500 scientists from 26 countries made this symposium the largest meeting ever held in the field. In this book twenty-six invited speakers comprehensively present their data on the pathogenesis of prion diseases in humans and animals, on molecular mechanisms involved in the transmissibility across species barriers, on animal and in-vitro models currently available for the detection and quantification of infectivity and on the characterization of prion strains.
