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Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all facets and phases of drug discovery, including target selection, biological testing, drug metabolism, and computer-assisted drug design. Drug Discovery features chapters written by an international team of pharmaceutical and medicinal chemists. Contribut...
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Advanced memory technologies are impacting the information era, representing a vibrant research area of huge interest in the electronics industry. The demand for data storage, computing performance and energy efficiency is increasing exponentially and will exceed the capabilities of current information technologies. Alternatives to traditional silicon technology and novel memory principles are expected to meet the need of modern data-intensive applications such as “big data” and artificial intelligence (AI). Functional materials or methodologies may find a key role in building novel, high speed and low power consumption computing and data storage systems. This book covers functional mate...
IJPHM Special issue on Wind Turbine PHM is the first special issue that discusses the state-of-the-art in PHM of wind turbine systems. This Special Issue contains 14 excellent papers that highlight a wide range of current research and application topics related to wind turbine PHM. Fault diagnostics is an important aspect of wind turbine PHM. Eight papers included in this special issue deal with fault diagnostics of different parts of a wind turbine. Each of these papers presents different fault diagnostic techniques and sensing technologies.
Early Continent Evolution of the North China Craton discusses the tectono-thermal regimes of the early continental crust in the North China Craton (NCC) from the Hadean to the early Paleoproterozoic, reconstructing the evolutional framework, and facilitating comprehensive understanding of the early continent evolution of the NCC. The book systematically summarizes the Neoarchean metamorphism of the NCC and discusses the implications for the tectonic models of the NCC, through compiling evolutional information of the Hadean to the early Paleoproterozoic sequences in the NCC. This allows for comprehensive summarizations and discussions on the tectonic framework of the NCC during this critical ...