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Recent Trends in Cytogenetic Studies - Methodologies and Applications deals with recent trends in cytogenetics with minute details of methodologies that can be adopted in clinical laboratories. The chapters deal with basic methods of primary cultures, cell lines and their applications; microtechnologies and automations; array CGH for the diagnosis of fetal conditions; approaches to acute lymphoblastic and myeloblastic leukemias in patients and survivors of atomic bomb exposure; use of digital image technology and using chromosomes as tools to discover biodiversity. While concentrating on the advanced methodologies in cytogenetic studies and their applications, authors have pointed out the need to develop cytogenetic labs with modern tools to facilitate precise and effective diagnosis to benefit the patient population.
This book, authored by renowned researchers in the field of Hypertension Research, details the state of the art knowledge in genetics, genomics and pathophysiology of Essential hypertension, specifically the genetic determinants of hypertension and role of gene variants in response to anti-hypertensive therapy. Two chapters describe mitochondrial mutations in Essential hypertension and in hypertension associated Left ventricular hypertrophy, one chapter reviews in detail the global gene expression in hypertension, and an up to date treatise on pathophysiology of resistant hypertension is detailed in another chapter. Other topics included in the book are end organ damage, baroreceptor sensitivity and role of music therapy in essential hypertension.
A síndrome metabólica é uma desordem complexa de base genética e origem multifatorial. O livro, que traz resultado de várias pesquisas de pós-graduação, trata desse sério problema de saúde que atinge muitas pessoas e é essencial para profissionais de saúde de todas as áreas, mas principalmente nutrição e medicina.
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Cytogenetics - Past, Present, and Further Perspectives discusses events that influenced the development of cytogenetics as a specialty within biology, with special attention paid to methodological achievements developed worldwide that have driven the field forward. Improvements to the resolution of chromosome analysis followed closely the introduction of innovative analytical technologies. In that sense, this book reviews and provides a brief account of the structure of chromosomes and stresses the high structural conservation in different species with an emphasis on aspects that require further research. However, it should be kept in mind that the future of cytogenetics will likely depend on improved knowledge of chromosome structure and function.
This edited book, Cytogenetics - Classical and Molecular Strategies for Analysing Heredity Material, presents recent advances in the field of cytogenetics, paying special attention to methodological achievements developed worldwide that have driven the field forward. The contributors clearly discuss several concepts and approaches useful for understanding chromosomal structure and function at its various levels, highlighting chromosomes as visible carriers of heredity material.
This is the first book to be devoted entirely to the application and development of flow techniques in cytogenetics. It provides comprehensive information on the use of flow cytometry and sorting for chromosome classification and purification. Cytogenetics and molecular biologists will find this book an invaluable reference source. - Practical details for the preparation and analysis of chromosomes using flow cytometry - Flow karyotyping for sensitive rapid analysis of chromosome normality and the detection of aberrant chromosomes - Flow sorting as a source of chromosome-specific DNA for gene mapping and recombinant DNA libraries - Construction and current status of chromosome-specific recombinant DNA libraries
15 chapters on protein phosphorylation and human health written by expert scientists. Covers most important research hot points, such as Akt, AMPK and mTOR. Bridges the basic protein phosphorylation pathways with human health and diseases. Detailed and comprehensive text with excellent figure illustration.
The expansion of the Cholas from their base in the Kaveri Delta saw this growing power subdue the kingdoms of southern India, as well as occupy Sri Lanka and the Maldives, by the early eleventh century. It was also during this period that the Cholas initiated links with Song China. Concurrently, the Southeast Asian polity of Sriwijaya had, through its Sumatran and Malayan ports, come to occupy a key position in East-West maritime trade, requiring engagement with both Song China to the north and the Chola kingdom to its west. The apparently friendly relations pursued were, however, to be disrupted in 1025 by Chola naval expeditions against fourteen key port cities in Southeast Asia. This volume examines the background, course and effects of these expeditions, as well as the regional context of the events. It brings to light many aspects of this key period in Asian history. Unprecedented in the degree of detail assigned to the story of the Chola expeditions, this volume is also unique in that it includes translations of the contemporary Tamil and Sanskrit inscriptions relating to Southeast Asia and of the Song dynasty Chinese texts relating to the Chola Kingdom.