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Intestinal Dysbiosis in Inflammatory Diseases
Dr. Fasano holds stocks in Alba Therapeutics and receives financial support from Takeda Pharmaceuticals. Dr. Taneja receives financial support from Elysium Health and Evelo Biosciences. The other Topic Editors declare no competing interests with regards to the Research Topic subject.
Understanding Crohn's Disease: Immunity, Genes and Microbes
Crohn's disease (CD) is a chronic, relapsing, inflammatory bowel disease resulting in considerable morbidity and reduced quality of life. Although still under intense debate, CD seems to result from an enhanced and uncontrolled immune response to the gut microbiota. CD is thought to be multifactorial depending on genetic and environmental determinants. In recent years, nearly 100 single nucleotide polymorphisms (SNPs) were associated with increased risk of developing CD (some of the SNPs also associated with susceptibility to ulcerative colitis, another type of IBD). These SNPs are mostly located in genes involved in innate and adaptive immunity mechanisms, such as autophagy, expression of p...
Global Transmission Expansion
Global Transmission Expansion: Recipes for Success covers everything you need to know to plan transmission expansion -from getting more from existing assets and understanding investors and their incentives to obtaining permits, rights of way, regulations, and performance standards--BOOK JACKET.
Advances in Mucosal Immunology
This monstrous, 1,660-page compilation of poster/oral presentations of the 7th Congress of Mucosal Immunology is loosely organized into functional components of respiratory, gut, and related cellular and solid organ components of the mucosal host/environment interface. It represents an attempt to capture the entire universe of mucosal immunology known in mid-1993, and herein lies the fatal flaw so common when attempting to publish congress proceedings (especially international) in timely fashion. Many a gamma/delta cell and mucosal related cytokine has visited the gut since that time! This potpourri contains papers that are almost all extremely brief and range from presentation of technical ...
Limb from Limb
He Used A Hand Saw. . . On Valentine's Day 2007, in a suburb of Detroit, stay-at-home dad Stephen Grant filed a missing person's report with the local sheriff. Grant's wife Tara had disappeared five days earlier. He'd been searching for her ever since--or so he claimed. He Started With Her Hands. . . Over the next two weeks, police questioned Grant. He lashed out, accusing them of harassment, pleading his innocence in television interviews. He swore that his wife, a successful businesswoman, had abandoned him and their children. Then the police made a gruesome discovery. . . He Kept Her Torso In The Garage. After his arrest, Grant confessed to strangling his wife and cutting her body into fo...
