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In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.
Following the structure and format of the ESC core syllabus, this text introduces key concepts in the field of cardiovascular medicine.
A definitive resource, The ESC Textbook of Cardiovascular Imaging, second edition provides extensive coverage of all cardiovascular imaging modalities. Produced in collaboration with the European Association of Cardiovascular Imaging with contributions from specialists across the globe and edited by a distinguished team of experts, it is a 'state of the art' clinically-orientated imaging reference. Now fully revised and updated with the latest imaging techniques and technology and covering even more conditions than before, it not only discusses the principles of individual modalities but also clearly demonstrates the added value each technique can bring to the treatment of all cardiac diseas...
The ESC Textbook of Cardiovascular Imaging 3e provides extensive coverage of all cardiovascular imaging modalities. Produced in collaboration with the European Association of Cardiovascular Imaging (affiliate of the European Society of Cardiology) with contributions from specialists across the globe and edited by a distinguished team of experts.
The 4th International Workshop on Medical Imaging and Augmented Reality, MIAR 2008, was held at the University of Tokyo, Tokyo, Japan during August 1–2, 2008. The goal of MIAR 2008 was to bring together researchersin medical imaging and intervention to present state-of-the-art developments in this ever-growing research area. Rapid technical advances in medical imaging, including its gr- ing application in drug/gene therapy and invasive/interventional procedures, have attracted signi?cant interest in the close integration of research in the life sciences, medicine, physical sciences, and engineering. Current research is also motivated by the fact that medical imaging is moving increasingly ...
During the past few years, cardiac CT (CCT) has acquired an increasingly important role as a noninvasive imaging method that allows assessment of coronary heart disease from both the morphological and the functional standpoint. It is quickly becoming a primary clinical tool for the evaluation and follow-up of various conditions related to the heart and great vessels and is providing valuable insights into the natural history of atherosclerosis. The rapid advances in CCT technology, the advent of new clinical applications, and the acquisition of data on prognostic value are just some of the reasons for the publication of this new edition of Clinical Applications of Cardiac CT, little more tha...
Since the introduction of myocardial perfusion imaging and radionuclide angiography in the mid-seventies, cardiovascular nuclear medicine has undergone an explosive growth. The use of nuclear cardiology techniques has become one of the cornerstones of the noninvasive assessment of coronary artery disease. In the past 15 years major steps have been made from visual analysis to quantitative analysis, from planar imaging to tomographic imaging, from detection of disease to prognosis, and from separate evaluations of perfusion, metabolism, and function to an integrated assessment of myocardial viability. In recent years many more advances have been made in cardiovascular nuclear imaging, such as the development of new imaging agents, reevaluation of existing procedures, and new clinical applications. This book describes the most recent developments in nuclear cardiology and also addresses new contrast agents in MRI. What's New in Cardiac Imaging will assist the clinical cardiologist, the cardiology fellow, the nuclear medicine physician, and the radiologist in understanding the most recent achievements in clinical cardiovascular nuclear imaging.
Myocardial viability has become one of the most important issues in clinical cardiology. In particular, absence or presence of viability may be decisive in patient management, and the decision to perform angioplasty (PTCA) or bypass surgery (CABG) is frequently based on the accurate assessment of viability. Although echocardiography and conventional nuclear medicine techniques may provide valuable information on viability, positron emission tomography (PET) is currently considered to be the gold standard for the assessment of myocardial viability. The simultaneous evaluation of myocardial metabolism and perfusion allows precise delineation and accurate quantification of residual myocardial v...
Plasticity and dynamism characterize the immune system as a tissue-integrating network with defensive functions. Blood and lymphatic vessel trees constitute the most evident and intuitive physical platform for the development of the net of interactions between immune cells, body tissues and foreign agents. Moreover vessel repair and immune patrolling are intimately linked physiological functions with common evolutionary roots. Not surprisingly variable degrees of vascular inflammation are often detectable in the setting of systemic inflammation and autoimmunity, whereas research in the field of cardiovascular pathology is progressively converging towards the identification of a common inflammatory background. The definition of the role of vascular inflammation in causing, sustaining and/or predicting the development of systemic autoimmunity constitute a challenging, unexplored frontier towards the development of a new generation of treatments and a better patient care.
Written by leading authorities in the field, Chest Pain with Normal Coronary Arteries comprehensively reviews the clinical presentation and the pathogenesis of the condition, as well as its management. This book provides a practical tool for the clinician and a bank of information and new ideas for research scientists and clinical researchers interested in understanding the causes and mechanisms of chest pain with normal coronary arteries. Whether the pain be of gastroenterologic, cardiac or endocrine in origin, the book focuses on effective diagnosis, treatment and management of different pathologies in patients. Chest Pain with Normal Coronary Arteries is an essential read for all clinicians involved in managing patients with chest pain, and those that should be aware of non-cardiac chest pain.