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Homocysteine and Vascular Disease
This is an important and timely volume. The history of research in homocysteine metabolism can be divided into three periods. The first phase was the exploration of the individual reactions and metabolites that characterize the transmethylation and transsulfuration sequences. The former originated with his description of the biosynthesis of methylpyridine and culminated in the work of Cantoni and Axelrod. Similarly the finding that insulin contained cystine was a potent catalyst for the metabolic and nutritional studies of Rose and du Vigneaud. The description and the definition of homocystinuria, a rare inherited meta bolic disorder, marked the beginning of the second historical period. Whe...
More on Mediterranean Diets
"This book is an update of the previous volume on Mediterranean diets published in 2000, which provided extensive reviews of the various diets existing in the Mediterranean region. Since then, a number of studies have been published on the relationship between a 'Mediterranean-type' diet and chronic diseases. However, because the 'diet score' used in those studies does not provide any information on the nutritional composition or quality of the diet, this publication takes an entirely different approach: Particular attention is given to the nutritional factors and their mechanisms in cardiovascular disease, cancer, metabolic syndrome and obesity, and the results of decreasing the [omega]-6:[omega]-3 ratio and its anti-inflammatory effects on several biomarkers are evaluated. Moreover, the effects of olive oil, relative to its antioxidant properties, and the anti-inflammatory and anticarcinogenic aspects of melatonin from plants and fruits common in the Mediterranean region are discussed."--BOOK JACKET.
Neural Nets and Surroundings
This volume collects a selection of contributions which has been presented at the 22nd Italian Workshop on Neural Networks, the yearly meeting of the Italian Society for Neural Networks (SIREN). The conference was held in Italy, Vietri sul Mare (Salerno), during May 17-19, 2012. The annual meeting of SIREN is sponsored by International Neural Network Society (INNS), European Neural Network Society (ENNS) and IEEE Computational Intelligence Society (CIS). The book – as well as the workshop- is organized in three main components, two special sessions and a group of regular sessions featuring different aspects and point of views of artificial neural networks and natural intelligence, also including applications of present compelling interest.
The Big Fat Surprise
Challenges popular misconceptions about fats and nutrition science, revealing the distorted claims of nutrition studies while arguing that more dietary fat can lead to better health, wellness, and fitness.
Homocysteine Metabolism: From Basic Science to Clinical Medicine
This volume is the first comprehensive treatise on homocysteine to treat the topic from the basic biochemical, metabolic, genetic, and dietary determinants to disease relationships, including concepts of pathogenesis. In addition, the public health implications of these associations are described. To date, evidence strongly supports the hypotheses that Hyperhomocysteinemia is a strong independent determinant of vascular disease and Many cases of hyperhomocysteinemia are amenable to homocysteine-lowering treatment with B-vitamins.£/LIST£ The strength of this evidence is prompting discussion of large-scale homocysteine-lowering interventions. Against this background of growing recognition of...
Antioxidants and Cardiovascular Disease
Generation of oxidants or reactive oxygen species is a natural process of human biology. Mitochondrial respiration, phagocytic activity and cyclooxygenase activation are all essential processes of life, which also generate oxidative species. In humans, chronic oxidative stress often coupled with deficiency of antioxidant defenses is associated with the aging process and can lead to the development of disorders such as cancer and arterial disease. Major cardiovascular conditions in which oxidative damage has been strongly implicated include atherosclerosis, myocardial ischemia and reperfusion, coronary restenosis and congestive heart failure. Compelling evidence points to oxidative stress as ...
Mediterranean Diets
Contrary to popular belief, there is no such thing as one Mediterranean diet: This geographic region includes several nations with varied cultures, traditions, incomes and dietary habits, resulting in a wide variation of dietary patterns. The present volume focuses on the latest research data from basic science and clinical intervention studies that indicate that a balanced ratio of omega-6 and omega-3 fatty acids and a high antioxidant intake from fruits and vegetables, along with olive oil, contribute to a lower rate of heart disease and increased longevity. These benefits are especially pronounced in the population of Crete, indicating that this diet is particularly healthy. Moreover, descriptions of the diets of Greece, Italy, Spain and the Maghreb are given for the first time, pointing to their differences as well as to their common dietary patterns; these are followed by chapters on the nutritional and metabolic contributions of antioxidants, wine, olive oil and fatty acids.
Cellular Metabolism of the Arterial Wall and Central Nervous System
International experts review the molecular biology of ion channels, diseases of the central nervous system including Alzheimer's disease, the molecular biology of atherogenesis, plasma lipproteins, lipid transport, long chain fatty acid transport and metabolism, and lipoprotein receptors. Future directions and perspectives and common features in these important areas are discussed.
Atherosclerosis III
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