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Complementary and Alternative Therapy for Pain Disorders: From Bench to Clinical Practice
Pain disorders pose significant challenges to global health and have a profound impact on the quality of life. It is estimated that approximately 20% of adults globally experience pain disorders, with 10% being newly diagnosed with chronic pain each year. Non-steroidal anti-inflammatory drugs (NSAIDs) are the main components of today’s first-line pain treatments, which largely combat inflammation and nociception. However, long-term consumption of these drugs often leads to various side effects and drug addiction. Therefore, it is crucial to investigate alternative pain management strategies with fewer adverse effects. Complementary and alternative therapy (CAT) as a viable option for pain control is becoming more widely acknowledged. CAT encompasses various modalities, including but not limited to transcutaneous electrical stimulation, herbal medicine, acupuncture, acupressure, Tuina, Gua Sha, moxibustion, Qigong, Tai Chi, acupoint catgut embedding, acupotomy, yoga, and meditation. Despite its growing acceptance, the effects and underlying scientific mechanisms of CAT for pain disorders remain incompletely understood, limiting its widespread use in clinical practice.
Purinergic Signaling in Neurodevelopment, Neuroinflammation and Neurodegeneration
This volume explores the quickly evolving field of Purinergic signaling, and examines how receptors for ATP and other nucleotides, and receptors for adenosine, act in neuronal transmission, control of synaptic activity, proliferation, differentiation and cell death regulation in the CNS. This book focuses on the participation of purinergic receptors and ectonucleotidases, degrading ATP into adenosine, in embryonic and adult neurogenesis in vitro and in vivo as well as in synaptic transmission and pathophysiology. Further, the chapters discuss varying brain diseases, including Parkinson’s, and Alzheimer’s disease, autism, mood disorders and epilepsy, as well as brain tumors, in the contex...
Pharmacology of Purine and Pyrimidine Receptors
This is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors. Authors are the leading authorities in their fields Subject matter is important for understanding tissue protection Subject matter is of intense interest for new drug development
Epic Films
Epic films, those concerned with monumental events and larger-than-life characters, cover the period from the Creation to the A.D. 1200's and have been churned out by Hollywood and overseas studios since the dawn of filmmaking. Arguably the master of the genre, Cecil B. DeMille hit upon the perfect mixture of sex, splendor, and the sacred to lure audiences to his epic productions. Each of the 225 alphabetically arranged entries in this book includes casts and credits, plot synopsis, and narratives on the making of the films. Many photographs enliven the text.
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Pharmacology of Purine and Pyrimidine Receptors
This is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors. - Authors are the leading authorities in their fields - Subject matter is important for understanding tissue protection - Subject matter is of intense interest for new drug development
