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Pre-Clinical Models
This volume details reviews and protocols on the development and analysis of both cellular and animal-based pre-clinical models in a number of medical areas, including metabolic disorders, longevity, cancer, heart disease and psychiatric disorders. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Pre-Clinical Models: Techniques and Protocols aims to provide methods that describe the context of specific disease or therapeutic areas.
My Index of Slightly Horrifying Knowledge
My Index of Slightly Horrifying Knowledge is a fierce and original collection—its generosity of voice and emotional range announce the arrival of a major new poet. At the age of twelve, Paul Guest suffered a bicycle accident that left him paralyzed for life. But out of sudden disaster evolved a fierce poetic sensibility—one that blossomed into a refuge for all the grief, fury, and wonder at life forever altered. Although its legacy lies in tragedy, the voice of these brilliant poems cuts a broad swath of emotions: whether he is lamenting the potentiality of physical experience or imagining the electric temptations of sexuality, Guest offers us a worldview that is unshakable in its humanity.
Notes for My Body Double
Who would guess that Godzilla, the Invisible Man, Elvis, Donald Duck, Ted Williams, and the Three Stooges might have something to say about the love and loss that shape the way we see the world? And yet these are the pop-culture coordinates that chart the emotional life brilliantly mapped out in Paul Guest?s second book of poems. Winner of the Prairie Schooner Prize in Poetry, this collection plumbs the depths of nature and culture (how, for instance, ?gar? in Old English means ?spear,? and an octopus can lose a limb during mating) to give form to the darkness and the light that make us human. ø In poetry whose tone is largely one of lament tempered by a wry and intelligent humor, Paul Guest does what a poet does best: he gives us the moments of his life refashioned to reflect the larger arc and meaning of our own?of life, that is, writ large.
Poetry Daily
A poem-a-day book from the Web's No. 1 poetry site
Hackers & Painters
The author examines issues such as the rightness of web-based applications, the programming language renaissance, spam filtering, the Open Source Movement, Internet startups and more. He also tells important stories about the kinds of people behind technical innovations, revealing their character and their craft.
The Most Important Comic Book on Earth
The Most Important Comic Book On Earth is a global collaboration for planetary change, bringing together a diverse team of 300 leading environmentalists, artists, authors, actors, filmmakers, musicians, and more to present over 120 stories to save the world. Whether it's inspirational tales from celebrity names such as Cara Delevingne and Andy Serkis, hilarious webcomics from War and Peas and Ricky Gervais, artworks by leading illustrators David Mack and Tula Lotay, calls to action from activists George Monbiot and Jane Goodall, or powerful stories by Brian Azzarello and Amy Chu, each of the comics in this anthology will support projects and organizations fighting to save the planet and Rewrite Extinction.
Truth-proof
None
The Violence of the Lamb
The act of martyrdom in the worldview of the Apocalypse has been considered to be an exemplification of non-violent resistance. Paul Middleton argues here, however, that it is in fact a representation of direct participation by Christians, through their martyrdom, in divine violence against those the author of Revelation portrays as God's enemies. Middleton shows that acceptance of martyrdom is to grasp the invitation to participate in the Revelation's divine violence. Martyrs follow the model laid down by the Lamb, who was not only slain, but resurrected, glorified, and who executes judgement. The world created by the Apocalypse encourages readers to conquer the Beast through martyrdom, but also through the experience of resurrection and being appointed judges. In this role, martyrs participate in the judgement of the wicked by sharing the Lamb's power to judge. Different from eschewing violence, the conceptual world of the Apocalypse portrays God, the Lamb, and the martyrs as possessing more power, might, and violent potential than the Emperor and his armies. Middleton believes that martyrdom and violence are necessary components of the worldview of Revelation.
Physical Exercise and Natural and Synthetic Products in Health and Disease
This detailed book explores protocols with the aim of testing aerobic exercise, resistance training, special diets, additives and natural products, which have led to new insights into the physiological and molecular aspects of health and disease. Many of these approaches have contributed to significant improvements in disease areas such as cardiovascular disease, cognitive dysfunction, diabetes, frailty, gliobastoma, metabolic syndrome, obesity, oxidative stress, and various cancers. This collection also provides important information on disease mechanisms and novel drug targets as each protocol is presented in the context of specific chronic diseases or different therapeutic areas. Written ...
