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In Pursuit of Health Equity
Throughout Latin America, social medicine has been widely recognized for its critical perspectives on mainstream understandings of health and for its progressive policy achievements. Nevertheless, it has been an elusive subject: hard to define, with puzzling historical discontinuities and misconceptions about its origins. Drawing on a vast archive and with an ambitious narrative scope that transcends national borders, Eric D. Carter offers the first comprehensive intellectual and political history of the social medicine movement in Latin America, from the early twentieth century to the present day. While maintaining a consistent focus on health equity, social medicine has evolved with changi...
When Chemistry Meets Biology – Generating Innovative Concepts, Methods and Tools for Scientific Discovery in the Plant Sciences
Biologically active small molecules have increasingly been applied in plant biology to dissect and understand biological systems. This is evident from the frequent use of potent and selective inhibitors of enzymes or other biological processes such as transcription, translation, or protein degradation. In contrast to animal systems, which are nurtured from drug research, the systematic development of novel bioactive small molecules as research tools for plant systems is a largely underexplored research area. This is surprising since bioactive small molecules bear great potential for generating new, powerful tools for dissecting diverse biological processes. In particular, when small molecule...
RNA Interference, Editing, and Modification
This volume presents a comprehensive collection of cuttingedge methods for elucidating the function of new genes and altering gene expression. These readily reproducible techniques can be used either in transient and stable gene splicing applied to worms, flies, trypanosomes, mammals, and plants, or in studying RNA editing mechanisms in a wide range of organisms, including systems that involve the conversion of one base to another and insertion/deletion editing. Topics of interest include stable and transient RNA interference, gene silencing, RNA editing, bioinformatics, small noncoding RNAs, and RNomics. Special attention is given to methods for the identification and characterization of small RNAs involved in RNA interference or modification. Readily reproducible protocols for discovering new genes or altering gene expression.
Genomes 5
Genomes 5 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with previous Genomes editions, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals, including humans and other hominids. Genome sequencing and assembly methods have been thoroughly revised to include new developments in long-read DNA sequencing. Coverage of genome annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge gained from these...
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Genomes 4
Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals including humans and other hominids. Genome sequencing and assembly methods have been thoroughly revised including a survey of four genome projects: human, Neanderthal, giant panda, and barley. Coverage of genome annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge ga...
Plant Phosphorus Nutrition
This book is an up-to-date reference on phosphorus nutrition in plants. Phosphorus has no substitute in food production, and the use of phosphate (Pi) fertilisers has increased crop yields to feed billions of people. This book covers phosphorus metabolism and phosphorus sensing molecular mechanisms and signalling in plants. It covers functions of phosphorus and crosstalk with other nutrients. It discusses how plants sense Pi deficiency and coordinate the responses via signalling pathways and networks for the regulation of Pi-deficiency responses. FEATURES Discusses the latest developments in phosphate management in plants Provides insights on emerging topics for sustainable approaches to managing phosphate shortage Throws light on the resilience of plants to phosphate deficiency Provides extensive updates that serve as primary points for further research Explains molecular and physiological mechanisms of phosphate transport This book compiles the latest research from experts in the field. It is useful for advanced graduates and researchers in plant sciences and agriculture.
