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Pauline Lukey first met Ppinder Hundal when Ppinder was eight years old, at which point Ppinder was non-verbal and had no formal way of communicating. This book charts their development together as, through the use of facilitated communication techniques, Ppinder has shown herself to be an eager and increasingly fluent communicator. Beginning with the use of sign language, moving on to assisted typing (the title of this book being drawn from the first spontaneous phrase that Ppinder typed) and finally to Ppinder's current desire to learn to read and write, both authors recount their remarkable journey from Ppinder's first signs (coat, more, cookie, and finish) to her ability now to discuss her medication with her carers and converse, via laptop, with her autistic friend. This honest and moving account demonstrates the remarkable effects of facilitated communication and highlights that communication is a skill that everyone is entitled to enjoy.
This book reviews successes and (remaining) challenges in vaccine development for the selected Neglected Tropical Diseases (NTD) of Leprosy, Leishmaniasis, Meliodoisis and Tuberculosis, which are a continuous burden for millions of people in affected areas worldwide. Written by frontline researchers, the volume deep-dives into different vaccine strategies, provides biotechnological background information and also tackles animal models in NTD therapeutics research. By bringing together state-of-the-art expert knowledge, the book contributes to the aim of ultimately ending the epidemics of neglected tropical diseases, complying with UN Sustainable Development Goal 3, Health and Well-Being. The volume highlights the activities of the research network VALIDATE (VAccine deveLopment for complex Intracellular neglecteD pAThogEns), funded by the Medical Research Council in the UK. The four NTDs discussed in the book were selected as these are in the focus of VALIDATE’s research. The book targets scientists and clinicians working on NTDs, as well as all readers with a background in biomedicine and interest in vaccine development. This is an open access book.
Based on many years of working with such people, many of whom have withdrawn into a world of their own, Phoebe Caldwell explores the different sensory reality they experience, showing it to be infinitely more complex and varied than is widely understood.
M. tuberculosis remains one of the most successful human pathogens known. The causative agent of tuberculosis, it also has a unique ability to persist for years in the infected, apparently healthy host. This dormant organism can be reactivated years, even decades later to cause tuberculosis. This book reviews the most important state-of-the-art approaches currently used to study microbe-host interactions and highlights emerging methodologies.
One in every five Americans lives with at least one disability or disorder, including both the obvious, such as those requiring the use of a wheelchair, and the less evident ones, such as eating disorders or Asperger's syndrome. Those responsible for teaching disabled students and providing services and support for them need ready access to reliable and up-to-date resources. Disabilities and Disorders in Literature for Youth: A Selective Annotated Bibliography for K-12 identifies almost 1,000 resources to help educators, professionals, parents, siblings, guardians, and students understand the various disabilities and disorders faced by children today. This bibliography consists of four major...
The aim of this book is to provide detailed protocols for studying the molecular biology of the pathogen Mycobacterium tuberculosis, and its int- actions with host cells. As established mycobacterial laboratories move - wards exploiting the genome, and laboratories with expertise in other fields apply them to mycobacteria, both traditional and novel methodologies need to be reviewed. Thus the chapters in Mycobacterium tuberculosis Protocols range from perspectives on storage of strains and safety issues to the application of the latest functional genomics technologies. The last few years have been remarkable ones for research into M. tuber- losis. The most important landmark by far has been ...
Includes Abstracts section, previously issued separately.