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The study of signal transduction mechanisms has become one of the most important branches of biomedical science, indispensable to understanding the normal actions of hormones, neurotransmitters and other extracellular signaling molecules as well as many pathophysiological processes, including inflammation and cancer. In this volume, the various techniques for measuring Ca2+ in the cytosol, in the various organelles, and in the immediate surroundings of individual cells are described in practical detail by experts. Also included is a chapter on tracking calmodulin inside cells using fluorescence technology. A Springer Lab Manual
"Throughout the 1970s and into the 1980s, in the wake of the installation of Brazil's military dictatorship, artists and art collectives in Brazil used their work to critique the government and its sanitized images of Brazil, its use of torture, and its targeted persecutions. Mari Rodríguez Binnie's The São Paulo Neo-Avant Garde studies this art and its engagement with politics and mainstream institutions and traditions. During this period São Paulo was home to a growing number of high-rise office buildings, and many of the artists studied here held day jobs that gave them after-hours access to new technologies of mass production that became foundational to their work. As the author write...
While scholars, activists and pundits from around the world have heralded the Lula years as a breakthrough for poverty reduction and the forthcoming emergence of Brazil as a dynamic economic superpower, many of their counterparts in the country as well as a number of Brazilianists elsewhere, have expressed great disappointment. Tracing back the trajectory of Brazilian Workers’ Party (Partido dos Trabalhadores - PT), Hernán F. Gómez Bruera explores how holding national executive public office contributed decisively to a pragmatic shift away from the party’s radical redistributive and participatory platform, earning the approbation of international audiences and criticisms of domestic pr...
This volume is concerned with examining the histories of freed slaves in a variety of slave societies in the ancient and modern world, ranging from ancient Rome to the southern states of the US, the Caribbean, and Brazil to Africa in the aftermath of emancipation in the twentieth century. The aim of this work is to present a comparative forum for the study of freedpeople. By identifying what is separate and what is universal about freedpeople it hopes to add to a better understanding of the role and impact of manumission and emancipation in different slave societies. Contributors include: Valentina Arena, Steeve Buckridge, Mariana Dantas, Marc Kleijwegt, Martin Klein, Rita Reynolds, Chandima Wickramasinghe, Swithin Wilmot, and Nigel Worden.
This edited volume offers a critical reflection on the failed experiment to redevelop the city of Rio de Janeiro according to the neoliberal strategy of entrepreneurial urban governance and mercantile regulatory transformations, which were leveraged by mega-sporting events. The case of Rio de Janeiro is presented as an example of a failing global strategy for urban redevelopment, entrepreneurial urban governance and the realization of mega-events. This book aims to present the real and critical state of the legacies of such mega-events. It shows how instead of the promised economic redemption, Rio is experiencing a severe economic, political and social crisis, handling three observation pers...
The Routledge Handbook of Private Law and Sustainability reflects on how the law can help tackle the current environmental challenges and make our societies more resilient to future crises. Sustainability has been high on the political agenda since the approval of the Sustainable Development Goals in 2015 and the EU Green Deal in 2019. The Green Agenda aims at making Europe the first climate‐neutral continent by 2050, but humanity persists in an ecological overshoot that puts at risk the survival of species, including that of our own. Drawing together a selection of leading thinkers in the field, this Handbook provides a curated overview of the most recent and relevant discussions for priv...
Blue Planet Law is the global and future-oriented environmental law that is necessary to face the global environmental crisis in the Anthropocene, assuming especially the link between climate action (SDG 13) and ocean sustainability (SDG 14). This open access book focuses on means of overcoming global environmental problems such as climate change, ocean degradation and biodiversity loss and the consequent risks for human life, health, food and wellbeing. It explores how environmental law, at the international, European and national levels, might set economic and technological development on a more sustainable path. Law must engage in dialogue with other areas such as philosophy, economics, e...
This book uses a unique typology of ten core drivers of injustice to explore and question common assumptions around what urban sustainability means, how it can be implemented, and how it is manifested in or driven by urban interventions that hinge on claims of sustainability. Aligned with critical environmental justice studies, the book highlights the contradictions of urban sustainability in relation to justice. It argues that urban neighbourhoods cannot be greener, more sustainable and liveable unless their communities are strengthened by the protection of the right to housing, public space, infrastructure and healthy amenities. Linked to the individual drivers, ten short empirical case st...