Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
T cell specificity and Cross-reactivity – Implications in Physiology and Pathology
Conventional CD8+ and CD4+ T cells recognize antigens, presented by antigen-presenting cells in the form of short peptides loaded onto major histocompatibility complex (MHC) class I and class II molecules, through their T cell receptor (TCR). Somatic gene rearrangement of the TCR locus and randomization of TCR hyper-variable regions generate the marked diversity of TCRs. Once assembled, the heterodimeric TCR confers specificity to naïve T cells. The naïve T cell repertoire of an individual is established by selection processes in the thymus and cannot be broadened upon antigen recognition by additional somatic mutations. In humans, the estimated number of distinct TCRs in the naïve T cell...
Immunoinformatics
This volume both engages the reader and provides a sound foundation for the use of immunoinformatics techniques in immunology and vaccinology. It addresses databases, HLA supertypes, MCH binding, and other properties of immune systems. The book contains chapters written by leaders in the field and provides a firm background for anyone working in immunoinformatics in one easy-to-use, insightful volume.
Artificial Immune Systems
Arti?cial Immune Systems have come of age. They are no longer an obscure computersciencetechnique,workedonbyacoupleoffarsightedresearchgroups. Today, researchers across the globe are working on new computer algorithms inspired by the workings of the immune system. This vigorous ?eld of research investigates how immunobiology can assist our technology, and along the way is beginning to help biologists understand their unique problems. AIS is now old enough to understand its roots, its context in the research community, and its exciting future. It has grown too big to be con?ned to s- cial sessions in evolutionary computation conferences. AIS researchers are now forming their own community and...
Bioinformatics for Immunomics
Like many words, the term “immunomics” equates to different ideas contingent on context. For a brief span, immunomics meant the study of the Immunome, of which there were, in turn, several different definitions. A now largely defunct meaning rendered the Immunome as the set of antigenic peptides or immunogenic proteins within a single microorganism – be that virus, bacteria, fungus, or parasite – or microbial population, or antigenic or allergenic proteins and peptides derived from the environment as a whole, containing also proteins from eukaryotic sources. However, times have changed and the meaning of immunomics has also changed. Other newer definitions of the Immunome have come to focus on the plethora of immunological receptors and accessory molecules that comprise the host immune arsenal. Today, Immunomics or immunogenomics is now most often used as a synonym for high-throughput genome-based immunology. This is the study of aspects of the immune system using high-throughput techniques within a conc- tual landscape borne of both clinical and biophysical thinking.
Bioinformatics in Personalized Medicine
This book constitutes the refereed proceedings of the 10th Spanish Symposium on Bioinformatics, JBI 2010, held in Torremolinos, Spain, in October 2010. The 13 revised full papers presented were carefully reviewed and selected from numerous submissions. The papers are structured in topical sections on next-generation sequencing data; genome-wide association studies; high-performanced databases; text-mining; tools for integration of Web services; ontologies; analysis and visualization of omics data.
In Silico Immunology
This book outlines three emergent disciplines, which are now poised to engineer a paradigm shift from hypothesis- to data-driven research: theoretical immunology, immunoinformatics, and Artificial Immune Systems. It details how these disciplines will enable new understanding to emerge from the analysis of complex datasets. Coverage shows how these three are set to transform immunological science and the future of health care.
The Fault in Our SARS
Proposes the pragmatic changes we must make to survive COVID and the worst of the new diseases on the horizon The Trump administration’s neglect and incompetence helped put half-a-million Americans in the ground, dead from COVID-19. Joe Biden was elected president in part on the promise of setting us on a science-driven course correction, but, a little more than a year later, another half-a-million Americans were killed by the virus. What happened? In The Fault in Our SARS, evolutionary epidemiologist Rob Wallace catalogs the Biden administration's failures in controlling the outbreak. He also shows that, beyond matters of specific political persona or party, it was a decades-long structur...
Robot 2019: Fourth Iberian Robotics Conference
This book gathers a selection of papers presented at ROBOT 2019 – the Fourth Iberian Robotics Conference, held in Porto, Portugal, on November 20th–22nd, 2019. ROBOT 2019 is part of a series of conferences jointly organized by the SPR – Sociedade Portuguesa de Robótica (Portuguese Society for Robotics) and SEIDROB – Sociedad Española para la Investigación y Desarrollo en Robótica (Spanish Society for Research and Development in Robotics). ROBOT 2019 built upon several previous successful events, including three biannual workshops and the three previous installments of the Iberian Robotics Conference, and chiefly focused on presenting the latest findings and applications in robotics from the Iberian Peninsula, although the event was also open to research and researchers from other countries. The event featured five plenary talks on state-of-the-art topics and 16 special sessions, plus a main/general robotics track. In total, after a stringent review process, 112 high-quality papers written by authors from 24 countries were selected for publication.
