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Over 25 million people in the U.S. alone have benefited from statins--such drugs as Lipitor, Zocor, Crestor, Pravachol, and other cholesterol-lowering medicines--in preventing stroke, heart attack, and other forms of coronary heart disease. But how did these remarkable, life-saving drugs come into being? In Triumph of the Heart, Dr. Jie Jack Li, a medicinal chemist and expert on drug discovery, tells for the first time the fascinating story of statins. Drawn from discussions with many scientists involved in the discovery and development of these drugs, the book illuminates the human side of science by revealing the role played by persistence, luck, and sudden insight that characterize major discoveries. For scientists in the drug industry, health care professionals, students of medicine, and all those intrigued by the basic human drive to explore and discover, Triumph of the Heart offers a compelling view of one of the most important drug discoveries of our time.
This book represents a first considered attempt to study the factors that conditioned industrial chemistry for war in 1914-18. Taking a comparative perspective, it reflects on the experience of France, Germany, Austria, Russia, Britain, Italy and Russia, and points to significant similarities and differences. It looks at changing patterns in the organisation of industry, and at the emerging symbiosis between science, industry and the military.
Do you have new and interesting – even outstanding – results that you wish to be recognized by your scientific colleagues, or understood by the public? Do you want to convey your ideas to policy decision makers? Communicating Science is the book to consult. Separate sections offer advice on reaching peers, the general public or decision makers. Each of these main parts includes two subsections, Guidelines and Genres, with entries arranged in alphabetical order. This book will be useful to anyone having to convert scientific data into an easily intelligible and interesting narrative.
In The Story of N, Hugh S. Gorman analyzes the notion of sustainability from a fresh perspective—the integration of human activities with the biogeochemical cycling of nitrogen—and provides a supportive alternative to studying sustainability through the lens of climate change and the cycling of carbon. It is the first book to examine the social processes by which industrial societies learned to bypass a fundamental ecological limit and, later, began addressing the resulting concerns by establishing limits of their own The book is organized into three parts. Part I, “The Knowledge of Nature,” explores the emergence of the nitrogen cycle before humans arrived on the scene and the chang...
The authors analyze Solvay's 150-year history, showing the enormous impact geopolitical events had on the company and the recent consequences of global competition.
An introductory guide that is designed particularly for teachers and their students, but is useful in many other contexts. This new edition lists reference works; histories of science and technology; histories of the chemical sciences and industries including company histories; autobiographies and biographies; edited classical texts; and journals.
Agust Nieto-Galan argues that chemistry in the twentieth century was deeply and profoundly political. Far from existing in a distinct public sphere, chemical knowledge was applied in ways that created strong links with industrial and military projects, and national rivalries and international endeavours, that materially shaped the living conditions of millions of citizens. It is within this framework that Nieto-Galan analyses how Spanish chemists became powerful ideological agents in different political contexts, from liberal to dictatorial regimes, throughout the century. He unveils chemists' position of power in Spain, their place in international scientific networks, and their engagement in fierce ideological battles in an age of extremes. Shared discourses between chemistry and liberalism, war, totalitarianism, religion, and diplomacy, he argues, led to advancements in both fields.
In the twentieth century, dyes, pharmaceuticals, photographic products, explosives, insecticides, fertilizers, synthetic rubber, fuels, and fibers, plastics, and other products have flowed out of the chemical industry and into the consumer economies, war machines, farms, and medical practices of industrial societies. The German chemical industry has been a major site for the development and application of the science-based technologies that gave rise to these products, and has had an important role as exemplar, stimulus, and competitor in the international chemical industry. This volume explores the German chemical industry's scientific and technological dimension, its international connections, and its development after 1945. The authors relate scientific and technological change in the industry to evolving German political and economic circumstances, including two world wars, the rise and fall of National Socialism, the post-war division of Germany, and the emergence of a global economy. This book will be of interest to historians of modern Germany, to historians of science and technology, and to business and economic historians.
Table of contents includes: Soap and Nicholas Leblanc, Color and William Henry Perkin, Sugar and Norbert Rillieux, Clean water and Edward Frankland, Fertilizer, poison gas, and Fritz Haber, Leaded gasoline, safe refrigeration and Thomas Midgley, Jr., Nylon and Wallace Hume Carothers, DDT and Paul Hermann Muller, Lead-free gasoline and Clair C. Patterson.
This volume is written as a reaction to the worldwide decreasing interest in the natural sciences. It addresses many intriguing questions. How is the changing image of the distinct sciences experienced by the general public, by the scientists themselves, or in disciplines in which natural sciences are applied? How can it be connected to the phenomenon of the low number of women in science? It is of interest to researchers, teachers, and students of natural sciences, the history of science, and philosophy.