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Confronted with an increase in floods, droughts and other natural hazards, cities and regions are alert to find climate proof solutions that overcome the limitations of traditional grey infrastructure. Nature-based solutions are proposed as a valid way to address risk and adapt to climate change while increasing resilience through the multiple benefits they generate. However, in spite of the widespread academic and political support for NBS, their implementation is lacking. As key barriers to implementation there are institutional and regulatory barriers, an absence of clear evaluation of NBS performance, funding/financing barriers and knowledge and acceptance barriers. This Open Access book...
This volume examines the applicability of nature-based solutions in ecological restoration practice and in contemporary landscape architecture by bringing together ecology and architecture in the built environment. Green infrastructure is used to address urban challenges such as climate change adaptation, disaster risk reduction, and stormwater management. In addition, thermal comfort nature-based solutions reintroduce critical connections between natural and urban systems. In light of ongoing developments in sustainable urban development, the goal is a paradigm shift towards a landscape that restores and rehabilitates urban ecosystems. The ten contributions to this book examine a wide range...
these analyses it became clear that the MHC class I molecule com prised a distinct groove on the external side of the molecule. The sides of the groove are formed by the a-helical structures of the a and a 1 2 domains and a floor which is formed by 8 anti-parallel 13 strands. The various polymorphic residues, as determined from DNA sequence analysis, are localized within these a-helices and 13-plated sheets within the groove. More importantly, these analyses also revealed the presence of elec tron-dense material in the groove. This material was subsequently iden 568 10 tified as a linear peptide of 8-10 amino acids long. • •- High resolu tion crystallographic analyses of the class I MHC ...
Netherlandish Books offers a unique overview of what was printed during the fifteenth and sixteenth centuries in the Low Countries. This bibliography lists descriptions of over 32,000 editions together with an introduction and indexes.
This volume is THE definitive, completely up-to-date, reference work for ALL researchers and clinicians working in autoimmunity.Up-to-Date: This is a timely critical review of more than 100 autoantibodies by leading experts in their respective fields, and includes many recent references.International Experts: The 120 Chapters have been written by the top international cadre of authors who have provided structured, expert contributions.Comprehensive: A total comprehensive perspective on the processes which induce, inhibit or otherwise affect autoantibodies in humans.Useful to Researchers and Clinicians: Chapters generally include methods of detection, pathogenic role, factors in pathogenicity and genetics as well as clinical utility with disease associations and frequencies.
A comprehensive reference work: This looseleaf work is an authoritative compilation of methods for the detection of autoantibodies (Section A: Methods of Autoantibody Detection); the structure, function, and molecular and biochemical concepts of autoantigens (Section B: Autoantigens); and the clinical significance of measuring autoantibodies in patients with rheumatic, connective tissue and autoimmune diseases (Section C: Clinical Significance of Autoantibodies). This unique work brings together all the molecular and medical information - very difficult to retrieve otherwise - in ONE publication. The Editors and contributors are leading experts in the immunological, molecular biological, and...
In the wake of the 1572 revolt against Spain, the new Dutch Republic outlawed Catholic worship and secularized all church property. Calvinism prevailed as the public faith, yet Catholicism experienced a resurgence in the first half of the seventeenth century, with membership rivaling that of the Calvinist church. In a wide-ranging analysis of a marginalized yet vibrant religious minority, Charles Parker examines this remarkable revival. It had little to do with the traditional Dutch reputation for tolerance. A keen sense of persecution, combined with a vigorous program of reform, shaped a movement that imparted meaning to Catholics in a Protestant republic. A pastoral organization known as t...